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Original Article

Inhibition of Oxidation of Low Density Lipoprotein by Vitamin E and Related Compounds

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Pages 123-134 | Received 02 May 1995, Accepted 16 Jun 1995, Published online: 07 Jul 2009

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Read on this site (8)

Takayuki Kaneko, Yuichiro Mita, Kanako Nozawa-Kumada, Masana Yazaki, Mieko Arisawa, Etsuo Niki, Noriko Noguchi & Yoshiro Saito. (2022) Antioxidant action of persulfides and polysulfides against free radical-mediated lipid peroxidation. Free Radical Research 56:9-10, pages 677-690.
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Yasukazu Yoshida, Nanako Itoh, Yoshiro Saito, Mieko Hayakawa & Etsuo Niki. (2004) Application of Water-Soluble Radical Initiator, 2,2′-Azobis-[2-(2-imidazolin-2-yl)propane] Dihydrochloride, to a Study of Oxidative Stress. Free Radical Research 38:4, pages 375-384.
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Karin Müller, Keri L.H. Carpenter, Mark A. Freeman & Malcolm J. Mitchinson. (1999) Antioxidant BO-653 and human macrophage-mediated LDL oxidation. Free Radical Research 30:1, pages 59-71.
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Noriko Noguchi & Etsuo Niki. (1998) Dynamics of Vitamin E Action against LDL Oxidation. Free Radical Research 28:6, pages 561-572.
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Tsutomu SASAKI, Jun YAMAKOSHI, Makoto SAITO, Kouichi KASAI, Takanao MATSUDO, Takuro KOGA & Kenji MORI. (1998) Antioxidative Activities of 4-Hydroxy-3(2H)-furanones and Their Anti-cataract Effect on Spontaneous Cataract Rat (ICR/f). Bioscience, Biotechnology, and Biochemistry 62:10, pages 1865-1869.
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Noriko Noguchi, Rika Numano, Hajime Kaneda & Etsuo Niki. (1998) Oxidation of lipids in low density lipoprotein particles. Free Radical Research 29:1, pages 43-52.
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Noriko Noguchi, Yoshiro SaitoEtsuo Niki. (2023) Actions of Thiols, Persulfides, and Polysulfides as Free Radical Scavenging Antioxidants. Antioxidants & Redox Signaling 39:10-12, pages 728-743.
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Luke A. Farmer, Zijun Wu, Jia-Fei Poon, Omkar Zilka, Svenja M. Lorenz, Stephanie Huehn, Bettina Proneth, Marcus Conrad & Derek A. Pratt. (2022) Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death. Journal of the American Chemical Society 144:32, pages 14706-14721.
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Etsuo Niki. (2021) Lipid oxidation that is, and is not, inhibited by vitamin E: Consideration about physiological functions of vitamin E. Free Radical Biology and Medicine 176, pages 1-15.
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Etsuo Niki. (2018) Oxidant-specific biomarkers of oxidative stress. Association with atherosclerosis and implication for antioxidant effects. Free Radical Biology and Medicine 120, pages 425-440.
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Romain Guitard, Véronique Nardello-Rataj & Jean-Marie Aubry. (2016) Theoretical and Kinetic Tools for Selecting Effective Antioxidants: Application to the Protection of Omega-3 Oils with Natural and Synthetic Phenols. International Journal of Molecular Sciences 17:8, pages 1220.
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K. Senthil Kumar & R. Kumaresan. (2011) A quantum chemical study on the antioxidant properties of aureusidin and bracteatin. International Journal of Quantum Chemistry 111:15, pages 4483-4496.
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Kiyoko Uno & Stephen J Nicholls. (2010) Biomarkers of inflammation and oxidative stress in atherosclerosis. Biomarkers in Medicine 4:3, pages 361-373.
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Etsuo Niki, Yo Omata, Akiko Fukuhara, Yoshiro Saito & Yasukazu Yoshida. (2008) Assessment of Radical Scavenging Capacity and Lipid Peroxidation Inhibiting Capacity of Antioxidant. Journal of Agricultural and Food Chemistry 56:18, pages 8255-8260.
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Etsuo Niki, Yasukazu Yoshida, Yoshiro Saito & Noriko Noguchi. (2005) Lipid peroxidation: Mechanisms, inhibition, and biological effects. Biochemical and Biophysical Research Communications 338:1, pages 668-676.
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Namakkal Soorappan Rajasekaran, Srinivasan Sathyanarayanan, Niranjali S. Devaraj & Halagowder Devaraj. (2005) Chronic depletion of glutathione (GSH) and minimal modification of LDL in vivo: its prevention by glutathione mono ester (GME) therapy. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1741:1-2, pages 103-112.
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Yasukazu Yoshida, Nanako Ito, Shuichi Shimakawa & Etsuo Niki. (2003) Susceptibility of plasma lipids to peroxidation. Biochemical and Biophysical Research Communications 305:3, pages 747-753.
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Shuichi Shimakawa, Yasukazu Yoshida & Etsuo Niki. (2003) Antioxidant action of a lipophilic nitroxyl radical, cyclohexane-1-spiro-2′-(4′-oxyimidazolidine-1′-oxyl)-5′-spiro-1″-cyclohexane, against lipid peroxidation under hypoxic conditions. Lipids 38:3, pages 225-231.
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Violeta G. RANEVA, Hiroyuki SHIMASAKI, Nobuo UETA & Jiro TAKAHASHI. (2003) Interaction between .ALPHA.-Tocopherol, Tocotrienols and Astaxanthin in Liposomes, Subjected to Lipid Peroxidation. Journal of Oleo Science 52:7, pages 347-352.
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Violeta Raneva, Hiroyuki Shimasaki, Yumi Furukawa, Nobuo Ueta, Nedyalka Yanishlieva, Jon Erik Aaseng, Vassilia Partali, Hans-Richard Sliwka, Yasukazu Yoshida & Etsuo Niki. (2002) Action of 1-(11-selenadodecyl)-glycerol and 1-(11-selenadodecyl)-3-trolox-glycerol against lipid peroxidation. Lipids 37:7, pages 633-640.
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Johanna Grassmann, Susanne Hippeli & Erich F Elstner. (2002) Plant’s defence and its benefits for animals and medicine: role of phenolics and terpenoids in avoiding oxygen stress. Plant Physiology and Biochemistry 40:6-8, pages 471-478.
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Hong-Yu Zhang & Lan-Fen Wang. (2002) Theoretical elucidation on structure–Antioxidant activity relationships for indolinonic hydroxylamines. Bioorganic & Medicinal Chemistry Letters 12:2, pages 225-227.
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Violeta Raneva, Hiroyuki Shimasaki, Yumi Ishida, Nobuo Ueta & Etsuo Niki. (2001) Antioxidative activity of 3,4-dihydroxyphenylacetic acid and caffeic acid in rat plasma. Lipids 36:10, pages 1111-1116.
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Noriko Noguchi & Etsuo Niki. (2000) Phenolic antioxidants:. Free Radical Biology and Medicine 28:10, pages 1538-1546.
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Angelo Azzi & Achim Stocker. (2000) Vitamin E: non-antioxidant roles. Progress in Lipid Research 39:3, pages 231-255.
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Oren TiroshJehoshua KatzhendlerYechezkel BarenholzRon Kohen. (1999) Low-Density Lipoprotein Oxidation and Its Prevention by Amidothionophosphate Antioxidants. Antioxidants & Redox Signaling 1:3, pages 325-338.
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Magdalena Pregetter, Ruth Prassl, Bernhard Schuster, Manfred Kriechbaum, Fabienne Nigon, John Chapman & Peter Laggner. (1999) Microphase Separation in Low Density Lipoproteins. Journal of Biological Chemistry 274:3, pages 1334-1341.
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Etsuo Niki. 1999. Advances in DNA Damage and Repair. Advances in DNA Damage and Repair 313 318 .
Takuro Koga, Keiko Moro & Junji Terao. (1998) Protective effect of a vitamin E analog, phosphatidylchromanol, against oxidative hemolysis of human erythrocytes. Lipids 33:6, pages 589-595.
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Jana Gallová, Peter M Abuja, Magdalena Pregetter, Peter Laggner & Ruth Prassl. (1998) Site-specific effect of radical scavengers on the resistance of low density lipoprotein to copper-mediated oxidative stress: influence of α-tocopherol and temperature. Chemistry and Physics of Lipids 92:2, pages 139-149.
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Noriko Noguchi, Hiromasa Yamashita, Naohiro Gotoh, Yuko Yamamoto, Rika Numano & Etsuo Niki. (1998) 2,2′-Azobis (4-Methoxy-2,4-Dimethylvaleronitrile), a New Lipid-Soluble Azo Initiator. Free Radical Biology and Medicine 24:2, pages 259-268.
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K. Fred Gey. (1998) Vitamins E plus C and interacting conutrients required for optimal health. BioFactors 7:1-2, pages 113-174.
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Noriko Noguchi, Naohiro Gotoh & Etsuo Niki. (1998) Action of vitamin E as antioxidant against oxidative modification of low density lipoprotein. BioFactors 7:1-2, pages 41-50.
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Barbara Karten, Ulrike Beisiegel, Günther Gercken & Anatol Kontush. (1997) Mechanisms of lipid peroxidation in human blood plasma: a kinetic approach. Chemistry and Physics of Lipids 88:2, pages 83-96.
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Etsuo Niki. (1997) Mechanisms and dynamics of antioxidant action of ubiquinol. Molecular Aspects of Medicine 18, pages 63-70.
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Noriko Noguchi, Hirokazu Sakai, Yoshinori Kato, Jyunichi Tsuchiya, Yuko Yamamoto, Etsuo Niki, Hiroyoshi Horikoshi & Tatsuhiko Kodama. (1996) Inhibition of oxidation of low density lipoprotein by troglitazone. Atherosclerosis 123:1-2, pages 227-234.
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