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Original Article

How Different Constituents of Low Density Lipoprotein Determine its Oxidizability by Copper: A Correlational Approach

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Pages 135-147 | Received 13 Mar 1995, Accepted 06 Jun 1995, Published online: 07 Jul 2009

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Halit Tanju Besler & Selçuk Çomogˇlu. (2003) Lipoprotein Oxidation, Plasma Total Antioxidant Capacity and Homocysteine Level in Patients with Multiple Sclerosis. Nutritional Neuroscience 6:3, pages 189-196.
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Anatol Kontush, Nicolette Donarski & Ulrike Beisiegel. (2001) Resistance of human cerebrospinal fluid to in vitro oxidation is directly related to its amyloid-β content. Free Radical Research 35:5, pages 507-517.
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Sönke Arlt, Barbara Finckh, Ulrike Beisiegel & Anatol Kontush. (2000) Time-course of oxidation of lipids in human cerebrospinal fluid in vitro. Free Radical Research 32:2, pages 103-114.
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Enrique Cadenas & Helmut Sies. (1998) The Lag Phase. Free Radical Research 28:6, pages 601-609.
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Articles from other publishers (32)

Anne Nègre-Salvayre, Nathalie Augé, Caroline Camaré, Titziana Bacchetti, Gianna Ferretti & Robert Salvayre. (2017) Dual signaling evoked by oxidized LDLs in vascular cells. Free Radical Biology and Medicine 106, pages 118-133.
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Meiying Ao, Chaoye Gan, Wenxiang Shao, Xing Zhou & Yong Chen. (2016) Effects of cyclodextrins on the structure of LDL and its susceptibility to copper-induced oxidation. European Journal of Pharmaceutical Sciences 91, pages 183-189.
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Ilya Pinchuk & Dov Lichtenberg. (2014) Analysis of the kinetics of lipid peroxidation in terms of characteristic time-points. Chemistry and Physics of Lipids 178, pages 63-76.
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Anna Tavridou, Apostolos Efthimiadis, Ioannis Efthimiadis & Vangelis G. Manolopoulos. (2010) Simvastatin-induced changes in circulating oxidized low-density lipoprotein in different types of dyslipidemia. Heart and Vessels 25:4, pages 288-293.
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Hyeon Ju LEE, Hyeon Chang KIM, Libor VITEK & Chung Mo NAM. (2010) Algae Consumption and Risk of Type 2 Diabetes: Korean National Health and Nutrition Examination Survey in 2005. Journal of Nutritional Science and Vitaminology Journal of Nutritional Science and Vitaminology 56:1, pages 13-18.
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Amal Zerrad-SaadiPatrice TherondSandrine ChantepieMartine CouturierKerry-Anne RyeM. John ChapmanAnatol Kontush. (2009) HDL3-Mediated Inactivation of LDL-Associated Phospholipid Hydroperoxides Is Determined by the Redox Status of Apolipoprotein A-I and HDL Particle Surface Lipid Rigidity. Arteriosclerosis, Thrombosis, and Vascular Biology 29:12, pages 2169-2175.
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Simona Baldi, Silvia Frascerra, Ele Ferrannini & Andrea Natali. (2007) LDL resistance to oxidation: Effects of lipid phenotype, autologous HDL and alanine. Clinica Chimica Acta 379:1-2, pages 95-100.
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Helmut Sies, Wilhelm Stahl & Alex Sevanian. (2005) Nutritional, Dietary and Postprandial Oxidative Stress. The Journal of Nutrition 135:5, pages 969-972.
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Sakae Ohkawa, Takashi Yoneyama, Kayoko Shimoi, Takako Takita, Yukitaka Maruyama & Hiromichi Kumagai. (2004) Pro-oxidative effect of α-tocopherol in the oxidation of LDL isolated from co-antioxidant-depleted non-diabetic hemodialysis patients. Atherosclerosis 176:2, pages 411-418.
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Lambertus J. H. van Tits, Tineke J. Smilde, Sanne van WissenJacqueline de Graaf, John J. P. KasteleinAnton F. H. Stalenhoef. (2023) Effects of Atorvastatin and Simvastatin on Low-Density Lipoprotein Subtraction Profile, Low-Density Lipoprotein Oxidizability, and Antibodies to Oxidized Low-Density Lipoprotein in Relation to Carotid Intima Media Thickness in Familial Hypercholesterolemia. Journal of Investigative Medicine 52:3, pages 177-184.
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Carsten Buhmann, Sönke Arlt, Anatol Kontush, Tobias Möller-Bertram, Sinje Sperber, Matthias Oechsner, Hans-Joerg Stuerenburg & Ulrike Beisiegel. (2004) Plasma and CSF markers of oxidative stress are increased in Parkinson's disease and influenced by antiparkinsonian medication. Neurobiology of Disease 15:1, pages 160-170.
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Stéphanie Zarev, Dominique Bonnefont-Rousselot, Iness Jedidi, Claudine Cosson, Martine Couturier, Alain Legrand, Jean-Louis Beaudeux & Patrice Thérond. (2003) Extent of copper LDL oxidation depends on oxidation time and copper/LDL ratio: chemical characterization. Archives of Biochemistry and Biophysics 420:1, pages 68-78.
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Marcel Wiedemann, Anatol Kontush, Barbara Finckh, Hans-Henning Hellwege & Alfried Kohlschütter. (2003) Neonatal Blood Plasma Is Less Susceptible to Oxidation Than Adult Plasma Owing to Its Higher Content of Bilirubin and Lower Content of Oxidizable Fatty Acids. Pediatric Research 53:5, pages 843-849.
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Alain Piolot, Denis Blache, Lucie Boulet, Louis Jacques Fortin, Denise Dubreuil, Caroline Marcoux, Jean Davignon & Suzanne Lussier-Cacan. (2003) Effect of fish oil on LDL oxidation and plasma homocysteine concentrations in health. Journal of Laboratory and Clinical Medicine 141:1, pages 41-49.
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Jan Hinrich Bräsen, Kai Koenig, Heiko Bach, Anatol Kontush, Helmut Heinle, Paul K. Witting, Seppo Ylä-Herttuala, Roland Stocker & Ulrike Beisiegel. (2002) Comparison of the effects of α-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits. Atherosclerosis 163:2, pages 249-259.
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W.Grady Smith, Jiang Wang, An Q Dang, Charles Reeves, David Bibbs & Fred H Faas. (2002) Gemfibrozil lowers plasma lipids and increases polyunsaturated fatty acid content and oxidative susceptibility of lipoproteins in hypertriglyceridemia. Clinica Chimica Acta 322:1-2, pages 77-84.
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Sönke Arlt, Anatol Kontush, Inga Zerr, Carsten Buhmann, Christian Jacobi, Andreas Schröter, Sigrid Poser & Ulrike Beisiegel. (2002) Increased Lipid Peroxidation in Cerebrospinal Fluid and Plasma from Patients with Creutzfeldt–Jakob Disease. Neurobiology of Disease 10:2, pages 150-156.
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Laurent Chancharme, Patrice Thérond, Fabienne Nigon, Stéphanie Zarev, Alain Mallet, Eric Bruckert & M. John Chapman. (2002) LDL particle subclasses in hypercholesterolemia: molecular determinants of reduced lipid hydroperoxide stability. Journal of Lipid Research 43:3, pages 453-462.
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W.Grady Smith, Charles Reeves, David Bibbs & Fred H Faas. (2002) Simple and rapid assessment of lipoprotein susceptibility to oxidation in the macromolecule fraction of plasma. Clinica Chimica Acta 316:1-2, pages 19-24.
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José Ignacio Ruiz-Sanz, Rosaura Navarro, Rosa Martı́nez, César Martı́n, Mercedes Lacort, Roberto Matorras & M.Begoña Ruiz-Larrea. (2001) 17β-Estradiol affects in vivo the low density lipoprotein composition, particle size, and oxidizability. Free Radical Biology and Medicine 31:3, pages 391-397.
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Peter G Scheffer, Stephan J L Bakker, Erik E Musch, Corrie Popp-Snijders, Robert J Heine & Tom Teerlink. (2000) Comparison of Three Methods for Measuring LDL Resistance against Copper-induced Oxidation. Clinical Chemistry 46:2, pages 291-294.
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Sven Schippling, Anatol Kontush, Sönke Arlt, Carsten Buhmann, Hans-Jörg Stürenburg, Ulrike Mann, Tomas Müller-Thomsen & Ulrike Beisiegel. (2000) Increased lipoprotein oxidation in alzheimer’s disease. Free Radical Biology and Medicine 28:3, pages 351-360.
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Dawn C. Schwenke, Janice D. Wagner & Michael R. Adams. (1999) In vitro lipid peroxidation of LDL from postmenopausal cynomolgus macaques treated with female hormones. Journal of Lipid Research 40:2, pages 235-244.
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Bedrich J Mosinger. (1999) Higher cholesterol in human LDL is associated with the increase of oxidation susceptibility and the decrease of antioxidant defence: experimental and simulation data. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1453:1, pages 180-184.
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Anatol Kontush & Ulrike Beisiegel. 1999. Oxidants and Antioxidants Part A. Oxidants and Antioxidants Part A 35 49 .
Luisa Tesoriere, Daniele D'Arpa, Aurelio Maggio, Vita Giaccone, Elisa Pedone & Maria A Livrea. (1998) Oxidation resistance of LDL is correlated with vitamin E status in β-thalassemia intermedia. Atherosclerosis 137:2, pages 429-435.
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Ouliana Ziouzenkova, Alex Sevanian, Peter M. Abuja, Pilar Ramos & Hermann Esterbauer. (1998) Copper Can Promote Oxidation of LDL by Markedly Different Mechanisms. Free Radical Biology and Medicine 24:4, pages 607-623.
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Torsten Spranger, Barbara Finckh, Ralph Fingerhut, Alfried Kohlschütter, Ulrike Beisiegel & Anatol Kontush. (1998) How different constituents of human plasma and low density lipoprotein determine plasma oxidizability by copper. Chemistry and Physics of Lipids 91:1, pages 39-52.
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Anatol Kontush, Axel Reich, Katja Baum, Torsten Spranger, Barbara Finckh, Alfried Kohlschütter & Ulrike Beisiegel. (1997) Plasma ubiquinol-10 is decreased in patients with hyperlipidaemia. Atherosclerosis 129:1, pages 119-126.
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Anatol Kontush, Torsten Spranger, Axel Reich, Sirus Djahansouzi, Barbara Karten, Jan Hinrich Braesen, Barbara Finckh, Alfried Kohlschütter & Ulrike Beisiegel. (2008) Whole plasma oxidation assay as a measure of lipoprotein oxidizability. BioFactors 6:2, pages 99-109.
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Anatol Kontush, Stefanie Meyer, Barbara Finckh, Alfried Kohlschütter & Ulrike Beisiegel. (1996) α-Tocopherol as a Reductant for Cu(II) in Human Lipoproteins. Journal of Biological Chemistry 271:19, pages 11106-11112.
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A Kontush, B Finckh, B Karten, A Kohlschütter & U Beisiegel. (1996) Antioxidant and prooxidant activity of alpha-tocopherol in human plasma and low density lipoprotein.. Journal of Lipid Research 37:7, pages 1436-1448.
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