43
Views
51
CrossRef citations to date
0
Altmetric
Original Article

Antioxidant Activity of Diethyldithiocarbamate

, , , &
Pages 461-472 | Received 09 Nov 1995, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Qais Bashir Jarrar, Muhammad Nazrul Hakim, Zainul Amiruddin Zakaria, Manraj Singh Cheema & Said Moshawih. (2020) Renal ultrastructural alterations induced by various preparations of mefenamic acid. Ultrastructural Pathology 44:1, pages 130-140.
Read now
Kazutaka Kanai, Yoshimasa Ito, Noriaki Nagai, Naoyuki Itoh, Yasutomo Hori, Seishirou Chikazawa, Fumio Hoshi & Seiichi Higuchi. (2012) Effects of Instillation of Eyedrops Containing Disulfiram and Hydroxypropyl-β-Cyclodextrin Inclusion Complex on Endotoxin-Induced Uveitis in Rats. Current Eye Research 37:2, pages 124-131.
Read now
Kazutaka Kanai, Naoyuki Itoh, Kazuki Yoshioka, Tomohiro Yonezawa, Hiromi Ikadai, Yasutomo Hori, Yoshimasa Ito, Noriaki Nagai, Seishirou Chikazawa, Fumio Hoshi & Seiichi Higuchi. (2010) Inhibitory Effects of Oral Disulfiram on Endotoxin-Induced Uveitis in Rats. Current Eye Research 35:10, pages 892-899.
Read now
Isaac Ginsburg, Shaul Yedgar & James Varani. (1997) Diethyldithiocarbamate and Nitric Oxide Synergize with Oxidants and with Membrane-Damaging Agents to Injure Mammalian Cells. Free Radical Research 27:2, pages 143-164.
Read now

Articles from other publishers (46)

Aliverdi Karimov, Parham Taslimi, Arzu Orujova, Khuraman Mammadova, Dursun Kısa, Vagif Farzaliyev, Afsun Sujayev, Nastaran Sadeghian, Tugba Taskin‐Tok, Saleh Alwasel & Ilhami Gulcin. (2023) Design, Synthesis, Characterization and Biological Activities of Novel S‐(Acyloxy)butyl‐N,N‐Diethyldithiocarbamate Compounds. ChemistrySelect 8:18.
Crossref
Marwa M. Abu-Serie & Eisayeda Zeinab A. Abdelfattah. (2022) Anti-metastatic breast cancer potential of novel nanocomplexes of diethyldithiocarbamate and green chemically synthesized iron oxide nanoparticles. International Journal of Pharmaceutics 627, pages 122208.
Crossref
Marina Solovieva, Yuri Shatalin, Irina Odinokova, Olga Krestinina, Yulia Baburina, Artem Mishukov, Yana Lomovskaya, Liubov Pavlik, Irina Mikheeva, Ekhson Holmuhamedov & Vladimir Akatov. (2022) Disulfiram oxy-derivatives induce entosis or paraptosis-like death in breast cancer MCF-7 cells depending on the duration of treatment. Biochimica et Biophysica Acta (BBA) - General Subjects 1866:9, pages 130184.
Crossref
Toluwani Tella, Ademuyiwa Adegbegi, Chiedu Emeninwa, Adekunle Odola, Ayansina Ayangbenro & Oluwatosin Adaramoye. (2022) Evaluation of the antioxidative potential of diisopropyldithiocarbamates sodium salt on diclofenac-induced toxicity in male albino rats. Toxicology Reports 9, pages 828-833.
Crossref
Nour-eddine Kaikai, Saadia Ba-M’hamed, Abderrazzak Ghanima & Mohamed Bennis. (2021) Metam sodium exposure during pregnancy and lactation in mice caused behavioral abnormalities and oxidative stress in offspring. Environmental Toxicology and Pharmacology 85, pages 103630.
Crossref
Segun D. Oladipo, Chunderika Mocktar & Bernard Omondi. (2020) In vitro biological studies of heteroleptic Ag(I) and Cu(I) unsymmetrical N,N′-diarylformamidine dithiocarbamate phosphine complexes; the effect of the metal center. Arabian Journal of Chemistry 13:8, pages 6379-6394.
Crossref
M.E. Solovieva, Yu.V. Shatalin, V.V. Solovyev, A.V. Sazonov, V.P. Kutyshenko & V.S. Akatov. (2019) Hydroxycobalamin catalyzes the oxidation of diethyldithiocarbamate and increases its cytotoxicity independently of copper ions. Redox Biology 20, pages 28-37.
Crossref
Natarajan Vijayasankaran, Sharat Varma, Yi Yang, Steven Meier & Robert Kiss. (2018) Effect of cell culture medium additives on color and acidic charge variants of a monoclonal antibody. Biotechnology Progress 34:5, pages 1298-1307.
Crossref
Seok Soon Park, Dong Min Lee, Jun Hee Lim, Dongjoo Lee, Sang Jun Park, Hwan Myung Kim, Seonghyang Sohn, Gyesoon Yoon, Young Woo Eom, Seong-Yun Jeong, Eun Kyung Choi & Kyeong Sook Choi. (2018) Pyrrolidine dithiocarbamate reverses Bcl-xL-mediated apoptotic resistance to doxorubicin by inducing paraptosis. Carcinogenesis 39:3, pages 458-470.
Crossref
Marcos M. Braga, Emerson S. Silva, Tarsila B. Moraes, Gabriel Henrique Schirmbeck, Eduardo P. Rico, Charles B. Pinto, Denis B. Rosemberg, Carlos S. Dutra-Filho, Renato D. Dias, Diogo L. Oliveira, João Batista T. Rocha & Diogo O. Souza. (2016) Brain zinc chelation by diethyldithiocarbamate increased the behavioral and mitochondrial damages in zebrafish subjected to hypoxia. Scientific Reports 6:1.
Crossref
Halina I. Falfushynska, Lesya L. Gnatyshyna & Oksana B. Stoliar. (2013) In situ exposure history modulates the molecular responses to carbamate fungicide Tattoo in bivalve mollusk. Ecotoxicology 22:3, pages 433-445.
Crossref
Tetiana M. Atamaniuk, Olga I. Kubrak, Viktor V. Husak, Kenneth B. Storey & Volodymyr I. Lushchak. (2013) The mancozeb-containing carbamate fungicide tattoo induces mild Oxidative Stress in goldfish brain, liver, and kidney. Environmental Toxicology, pages n/a-n/a.
Crossref
I. Rahden-Staroń, E. Grosicka-Maciąg, D. Kurpios-Piec, H. Czeczot, T. Grzela & M. Szumiło. (2012) The effects of sodium diethyldithiocarbamate in fibroblasts V79 cells in relation to cytotoxicity, antioxidative enzymes, glutathione, and apoptosis. Archives of Toxicology 86:12, pages 1841-1850.
Crossref
Olga I. Kubrak, Tetiana M. Atamaniuk, Viktor V. Husak, Ivanna Z. Drohomyretska, Janet M. Storey, Kenneth B. Storey & Volodymyr I. Lushchak. (2012) Oxidative stress responses in blood and gills of Carassius auratus exposed to the mancozeb-containing carbamate fungicide Tattoo. Ecotoxicology and Environmental Safety 85, pages 37-43.
Crossref
J. Llorente, M. T. Santamarta, G. Henderson & J. Pineda. (2012) Enhancement of  -Opioid Receptor Desensitization by Nitric Oxide in Rat Locus Coeruleus Neurons: Involvement of Reactive Oxygen Species. Journal of Pharmacology and Experimental Therapeutics 342:2, pages 552-560.
Crossref
Laetitia Knockaert, Alain Berson, Catherine Ribault, Pierre-Emmanuel Prost, Alain Fautrel, Julie Pajaud, Sylvie Lepage, Catherine Lucas-Clerc, Jean-Marc Bégué, Bernard Fromenty & Marie-Anne Robin. (2011) Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver. Laboratory Investigation 92:3, pages 396-410.
Crossref
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 46 .
Andrea Luna-Acosta, Eric Rosenfeld, Myriam Amari, Ingrid Fruitier-Arnaudin, Paco Bustamante & H?l?ne Thomas-Guyon. (2010) First evidence of laccase activity in the Pacific oyster Crassostrea gigas. Fish & Shellfish Immunology 28:4, pages 719-726.
Crossref
Robert Gealy, Jennifer L. Wright-Bourque, Andrew R. Kraynak, Troy W. McKelvey, John E. Barnum & Richard D. Storer. (2007) Validation of a high-throughput in vitro alkaline elution/rat hepatocyte assay for DNA damage. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 629:1, pages 49-63.
Crossref
Galen M. Pieper. 2007. Radicals for Life. Radicals for Life 407 422 .
Joseph SteinerNorman HaugheyWenxue LiArun VenkatesanCaroline AndersonRollie ReidTanya MalpicaChava PocernichD. Allan ButterfieldAvindra Nath. (2006) Oxidative Stress and Therapeutic Approaches in HIV Dementia. Antioxidants & Redox Signaling 8:11-12, pages 2089-2100.
Crossref
Malka Hochberg, Ron Kohen & Claes D. Enk. (2006) Role of antioxidants in prevention of pyrimidine dimer formation in UVB irradiated human HaCaT keratinocytes. Biomedicine & Pharmacotherapy 60:5, pages 233-237.
Crossref
Chava B. Pocernich, Rukhsana Sultana, Hafiz Mohmmad-Abdul, Avindra Nath & D. Allan Butterfield. (2005) HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations. Brain Research Reviews 50:1, pages 14-26.
Crossref
Galen M. Pieper, Ashwani K. Khanna, Bal N. Kampalath, Christopher C. Felix, Gail Hilton, Christopher P. Johnson, Mark B. Adams & Allan M. Roza. (2004) Inhibition of Nitrosylation, Nitration, Lymphocyte Proliferation, and Gene Expression in Acute and Delayed Cardiac Allograft Rejection by an Orally Active Dithiocarbamate. Journal of Cardiovascular Pharmacology 43:4, pages 522-530.
Crossref
Galen M. Pieper, Vani Nilakantan, Gail Hilton, Nadine L. N. Halligan, Christopher C. Felix, Bal Kampalath, Ashwani K. Khanna, Allan M. Roza, Christopher P. Johnson & Mark B. Adams. (2003) Mechanisms of the protective action of diethyldithiocarbamate-iron complex on acute cardiac allograft rejection. American Journal of Physiology - Heart and Circulatory Physiology 284:5, pages H1542-H1551.
Crossref
Kunio Ohyama, Takenori Akaike, Chieko Hirobe & Toshio Yamakawa. (2003) Cytotoxicity and Apoptotic Inducibility of Vitex agnus-castus Fruit Extract in Cultured Human Normal and Cancer Cells and Effect on Growth. Biological & Pharmaceutical Bulletin 26:1, pages 10-18.
Crossref
Annika M. Svensson, Stellan Sandler & Leif Jansson. (2003) Role of superoxide anion in pancreatic islet blood flow regulation in anesthetized rats. European Journal of Pharmacology 459:1, pages 59-64.
Crossref
Ben-Zhan Zhu, Anitra C Carr & Balz Frei. (2002) Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage. FEBS Letters 532:1-2, pages 80-84.
Crossref
Robert A. DiSilvestro, David L. Rogers & Haeyun G. Lee. (2002) Diethyldithiocarbamate inhibition of galactosamine-induced hepatitis in rats. Pharmacological Research 45:3, pages 253-255.
Crossref
Rafik Galimzyanovich Saifutdinov, Lyudmila Ivanovna Larina, Tamara Il’inichna Vakul’skaya & Mikhail Grigor’evich Voronkov. 2002. Electron Paramagnetic Resonance in Biochemistry and Medicine. Electron Paramagnetic Resonance in Biochemistry and Medicine 75 238 .
Kunio Ohyama, Bo Yuan, Toshio Bessho & Toshio Yamakawa. (2001) Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents . European Journal of Biochemistry 268:23, pages 6182-6189.
Crossref
Shane R. Thomas, Houta Salahifar, Ryuichi Mashima, Nicholas H. Hunt, Des R. Richardson & Roland Stocker. (2001) Antioxidants Inhibit Indoleamine 2,3-Dioxygenase in IFN-γ-Activated Human Macrophages: Posttranslational Regulation by Pyrrolidine Dithiocarbamate. The Journal of Immunology 166:10, pages 6332-6340.
Crossref
Shirley Teng, Kristin Beard, Jalal Pourahmad, Majid Moridani, Elaine Easson, Raymond Poon & Peter J O'Brien. (2001) The formaldehyde metabolic detoxification enzyme systems and molecular cytotoxic mechanism in isolated rat hepatocytes. Chemico-Biological Interactions 130-132, pages 285-296.
Crossref
Hirotaka Matsumura, Yusuke Shimizu, Yoshiyuki Ohsawa, Atsuo Kawahara, Yasuo Uchiyama & Shigekazu Nagata. (2000) Necrotic Death Pathway in FAS Receptor Signaling. The Journal of Cell Biology 151:6, pages 1247-1256.
Crossref
Aiping Zhao, Zheng-Qi Wu, Matthew Pollack, Florence M Rollwagen, Przemyslaw Hirszel & Xiaoming Zhou. (2000) DISULFIRAM INHIBITS TNF-?-INDUCED CELL DEATH. Cytokine 12:9, pages 1356-1367.
Crossref
Heinrich Sauer, Gohar Rahimi, Jürgen Hescheler & Maria Wartenberg. (2000) Role of reactive oxygen species and phosphatidylinositol 3-kinase in cardiomyocyte differentiation of embryonic stem cells. FEBS Letters 476:3, pages 218-223.
Crossref
John J.E. Haddad, Richard E. Olver & Stephen C. Land. (2000) Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1α and NF-κB Redox Sensitivity. Journal of Biological Chemistry 275:28, pages 21130-21139.
Crossref
Aruna Nathan & Mervyn Singer. 2000. Multiple Organ Failure. Multiple Organ Failure 167 175 .
Melissa K Johnson, Karen E Alexander, Niels Lindquist & George Loo. (1999) Potent antioxidant activity of a dithiocarbamate-related compound from a marine hydroid. Biochemical Pharmacology 58:8, pages 1313-1319.
Crossref
Zijian Guo & Peter J. Sadler. 1999. 183 306 .
Ann F. Haas, Jon W. Wong, Christine K. Iwahashi, Barry Halliwell, Carroll E. Cross & Paul A. Davis. (1998) Redox regulation of wound healing? NF-κB activation in cultured human keratinocytes upon wounding and the effect of low energy HeNe irradiation. Free Radical Biology and Medicine 25:9, pages 998-1005.
Crossref
Carys L Mitchelmore, Claudia Birmelin, J Kevin Chipman & David R Livingstone. (1998) Evidence for cytochrome P-450 catalysis and free radical involvement in the production of DNA strand breaks by benzo[a]pyrene and nitroaromatics in mussel (Mytilus edulis L.) digestive gland cells. Aquatic Toxicology 41:3, pages 193-212.
Crossref
Bysani Chandrasekar, John E Streitman, James T Colston & Gregory L Freeman. (1998) Inhibition of nuclear factor κB attenuates proinflammatory cytokine and inducible nitric-oxide synthase expression in postischemic myocardium. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1406:1, pages 91-106.
Crossref
Hakim Karoui, Bernhard Hansert, Patrick J. Sand, Paul Tordo, D.Scott Bohle & B. Kalyanaraman. (1997) Spin-Trapping of Free Radicals Formed during the Oxidation of Glutathione by Tetramethylammonium Peroxynitrite. Nitric Oxide 1:4, pages 346-358.
Crossref
Ian Stott, Anupama Murthy, Alex Robinson, Norman W Thomas & Jeffrey R Fry. (2016) Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1,3-Dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat. Human & Experimental Toxicology 16:5, pages 262-266.
Crossref
Gerald Scott. 1997. Antioxidants in Science, Technology, Medicine and Nutrition. Antioxidants in Science, Technology, Medicine and Nutrition 191 261 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.