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Original Article

Ascorbic Acid Inhibits Lipid Peroxidation but Enhances DNA Damage in Rat Liver Nuclei Incubated with Iron Ions

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Pages 585-592 | Received 18 Nov 1996, Published online: 07 Jul 2009

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Paulina Kazmierska, Jacek Grebowski & Jan Konopacki. (2012) Does an anti‐oxidant ascorbic acid improve the condition of hippocampal formation slice preparations? – a micro‐ EEG approach . International Journal of Experimental Pathology 93:6, pages 406-413.
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Chin-Shiu Huang & Miao-Lin Hu. (2011) Lycopene inhibits DNA damage and reduces hMTH1 mRNA expression in the liver of Mongolian gerbils treated with ferric nitrilotriacetate. Food and Chemical Toxicology 49:6, pages 1381-1386.
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Ruth Chan, Kris Lok & Jean Woo. (2009) Prostate cancer and vegetable consumption. Molecular Nutrition & Food Research 53:2, pages 201-216.
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Susanne Häussler & Tanja Becker. (2008) The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations. PLoS Pathogens 4:9, pages e1000166.
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R.John Aitken, Jordana K. Wingate, Geoffry N. De Iuliis & Eileen A. McLaughlin. (2007) Analysis of lipid peroxidation in human spermatozoa using BODIPY C11. MHR: Basic science of reproductive medicine 13:4, pages 203-211.
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Chantal Bémeur, Line Ste-Marie, Paul Desjardins, Luc Vachon, Roger F. Butterworth, Alan S. Hazell & Jane Montgomery. (2005) Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat. Neurochemistry International 46:5, pages 399-407.
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Evgeny Denisov & Igor Afanas’ev. 2005. Oxidation and Antioxidants in Organic Chemistry and Biology. Oxidation and Antioxidants in Organic Chemistry and Biology 1 284 .
Jane Higdon & Balz Frei. 2004. Cancer Chemoprevention. Cancer Chemoprevention 485 510 .
Shu-Lan Yeh, Tsai-Hsiu Yang, Chin-Hsiu Huang & Miao-Lin Hu. (2003) Exposure of calf thymus DNA to autoxidized β-carotene results in the formation of 8-oxo-deoxyguanosine. Food Chemistry 81:3, pages 439-445.
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Balz Frei & Ben-Zhan Zhu. 2003. Antioxidants. Antioxidants.
Kazuyuki Hiramoto, Yoshinobu Yasuhara, Ken-ichi Sako, Kazuhiro Aoki & Kiyomi Kikugawa. (2003) Suppression of Free Radical-Induced DNA Strand Breaks by Linoleic Acid and Low Density Lipoprotein in Vitro. Biological and Pharmaceutical Bulletin 26:8, pages 1129-1134.
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Yu-Ying He & Donat-P. Häder. (2002) UV-B-induced formation of reactive oxygen species and oxidative damage of the cyanobacterium Anabaena sp.: protective effects of ascorbic acid and N-acetyl-l-cysteine. Journal of Photochemistry and Photobiology B: Biology 66:2, pages 115-124.
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Shu-Lan Yeh & Miao-Lin Hu. (2000) Antioxidant and pro-oxidant effects of lycopene in comparison with β-carotene on oxidant-induced damage in Hs68 cells. The Journal of Nutritional Biochemistry 11:11-12, pages 548-554.
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Yong-Fa Wang & Miao-Lin Hu. (2000) Use of rat liver slices for the study of oxidative DNA damage in comparison with isolated rat liver nuclei and HepG2 human hepatoma cells. Food and Chemical Toxicology 38:5, pages 451-458.
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Chiu-Luan Hsieh & Gow-Chin Yen. (2000) Antioxidant actions of Du-zhong (Eucommia ulmoides oliv.) toward oxidative damage in biomolecules. Life Sciences 66:15, pages 1387-1400.
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Anitra Carr & Balz Frei. (1999) Does vitamin C act as a pro‐oxidant under physiological conditions?. The FASEB Journal 13:9, pages 1007-1024.
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Ming-Kuei Shih & Miao-Lin Hu. (1999) UVA-induced oxidative damage to rat liver nuclei: reduction of iron ions and the relationship between lipid peroxidation and DNA damage. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 438:2, pages 125-132.
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Adrianne M.M. Ball & Michael J. Sole. (1998) OXIDATIVE STRESS AND THE PATHOGENESIS OF HEART FAILURE. Cardiology Clinics 16:4, pages 665-675.
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