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Free Radical Research Volume 28, 1998 - Issue 1
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Original Article

Nasal Cavity Lining Fluid Ascorbic Acid Concentration Increases in Healthy Human Volunteers Following Short Term Exposure to Diesel Exhaust

A. Blomberg Department of Pulmonay Medicine and Allergology, University Hospital of Northern Sweden and National Institute for Working Life, Medical Division, Umeå, Sweden
,
C. Sainsbury Cardiovascular Research, The Rayne Institute, St. Thomas' Hospital, London, UK, SE1 7EH
,
B. Rudell Department of Occupationa1 Medicine, University Hospital of Northern Sweden, Umeå, Sweden
,
A. J. Frew Air Pollution Group, University Medicine, University of Southampton, Southampton, UK
,
S. T. Holgate Air Pollution Group, University Medicine, University of Southampton, Southampton, UK
,
T. Sandströw Department of Pulmonay Medicine and Allergology, University Hospital of Northern Sweden and National Institute for Working Life, Medical Division, Umeå, Sweden
&
F. J. Kelly Cardiovascular Research, The Rayne Institute, St. Thomas' Hospital, London, UK, SE1 7EHCorrespondence[email protected]
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Pages 59-67 | Received 19 Aug 1997, Accepted 17 Sep 1997, Published online: 07 Jul 2009

Citations (20)

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Jason Allen, Carol A. Trenga, Alon Peretz, Jeffrey H. Sullivan, Christopher C. Carlsten & Joel D. Kaufman. (2009) Effect of diesel exhaust inhalation on antioxidant and oxidative stress responses in adults with metabolic syndrome. Inhalation Toxicology 21:13, pages 1061-1067.
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L. Nikasinovic, I. Momas & J. Just. (2004) A REVIEW OF EXPERIMENTAL STUDIES ON DIESEL EXHAUST PARTICLES AND NASAL EPITHELIUM ALTERATIONS. Journal of Toxicology and Environmental Health, Part B 7:2, pages 81-104.
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Articles from other publishers (18)

Erin Long, Carley Schwartz & Christopher Carlsten. (2022) Controlled human exposure to diesel exhaust: a method for understanding health effects of traffic-related air pollution. Particle and Fibre Toxicology 19:1.
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Erin Long & Christopher Carlsten. (2022) Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions. Particle and Fibre Toxicology 19:1.
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Heather L. Shearer, James C. Paton, Mark B. Hampton & Nina Dickerhof. (2022) Glutathione utilization protects Streptococcus pneumoniae against lactoperoxidase-derived hypothiocyanous acid. Free Radical Biology and Medicine 179, pages 24-33.
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N. Larsson, G. D. Rankin, E. M. Bicer, E. Roos-Engstrand, J. Pourazar, A. Blomberg, I. S. Mudway & A. F. Behndig. (2015) Identification of vitamin C transporters in the human airways: a cross-sectional in vivo study. BMJ Open 5:4, pages e006979-e006979.
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Talat Islam, Robert Urman, W. James Gauderman, Joel Milam, Fred Lurmann, Ketan Shankardass, Ed Avol, Frank Gilliland & Rob McConnell. (2011) Parental Stress Increases the Detrimental Effect of Traffic Exposure on Children's Lung Function. American Journal of Respiratory and Critical Care Medicine 184:7, pages 822-827.
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Ketan ShankardassRob McConnell, Michael Jerrett, Joel Milam, Jean Richardson & Kiros Berhane. (2009) Parental stress increases the effect of traffic-related air pollution on childhood asthma incidence. Proceedings of the National Academy of Sciences 106:30, pages 12406-12411.
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Frank Kelly & Ian Mudway. 2006. Particle Toxicology. Particle Toxicology 89 117 .
Bettina C. Schock, John Koostra, Sunye Kwack, Robert M. Hackman, Albert van der Vliet & Carroll E. Cross. (2004) Ascorbic acid in nasal and tracheobronchial airway lining fluids. Free Radical Biology and Medicine 37:9, pages 1393-1401.
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Ian S Mudway, Nikolai Stenfors, Sean T Duggan, Heather Roxborough, Hendrick Zielinski, Stephan L Marklund, Anders Blomberg, Anthony J Frew, Thomas Sandström & Frank J Kelly. (2004) An in vitro and in vivo investigation of the effects of diesel exhaust on human airway lining fluid antioxidants. Archives of Biochemistry and Biophysics 423:1, pages 200-212.
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Ning Li, Minqi Hao, Robert F. Phalen, William C. Hinds & Andre E. Nel. (2003) Particulate air pollutants and asthma. Clinical Immunology 109:3, pages 250-265.
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Theresa M Bastain, Frank D Gilliland, Yu-Fen Li, Andrew Saxon & David Diaz-Sanchez. (2003) Intraindividual reproducibility of nasal allergic responses to diesel exhaust particles indicates a susceptible phenotype. Clinical Immunology 109:2, pages 130-136.
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David Diaz-Sanchez, Lidia Proietti & Riccardo Polosa. (2003) Diesel fumes and the rising prevalence of atopy: An urban legend?. Current Allergy and Asthma Reports 3:2, pages 146-152.
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D. Diaz‐Sanchez. (2008) Pollution and the immune response: atopic diseases – are we too dirty or too clean?. Immunology 101:1, pages 11-18.
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Andrew J. Ghio, Judy H. Richards, Jacqueline D. Carter & Michael C. Madden. (2016) Accumulation of Iron in the Rat Lung after Tracheal Instillation of Diesel Particles. Toxicologic Pathology 28:4, pages 619-627.
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JULIA A. NIGHTINGALE, RICHARD MAGGS, PAUL CULLINAN, LOUISE E. DONNELLY, DUNCAN F. ROGERS, ROBERT KINNERSLEY, K. FAN CHUNG, PETER J. BARNES, MICHAEL ASHMORE & ANTHONY NEWMAN-TAYLOR. (2000) Airway Inflammation after Controlled Exposure to Diesel Exhaust Particulates. American Journal of Respiratory and Critical Care Medicine 162:1, pages 161-166.
Crossref
Henryk ZielinskiIan S. Mudway, Kelly A. Bérubé, Samantha Murphy, Roy Richards & Frank J. Kelly. (1999) Modeling the interactions of particulates with epithelial lining fluid antioxidants. American Journal of Physiology-Lung Cellular and Molecular Physiology 277:4, pages L719-L726.
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B. Rudell, U. Wass, P. Horstedt, J. O. Levin, R. Lindahl, U. Rannug, A. L. Sunesson, Y. Ostberg & T. Sandstrom. (1999) Efficiency of automotive cabin air filters to reduce acute health effects of diesel exhaust in human subjects. Occupational and Environmental Medicine 56:4, pages 222-231.
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Albert van der VlietCharles A. O’Neill, Carroll E. CrossJohn M. KoostraWilliam G. VolzBarry Halliwell & Samuel Louie. (1999) Determination of low-molecular-mass antioxidant concentrations in human respiratory tract lining fluids. American Journal of Physiology-Lung Cellular and Molecular Physiology 276:2, pages L289-L296.
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