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Research Article

Modified nanoparticles with cell-penetrating peptide and amphipathic chitosan derivative for enhanced oral colon absorption of insulin: preparation and evaluation

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Pages 2003-2014 | Received 10 Mar 2015, Accepted 02 May 2015, Published online: 16 Jul 2015

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Swapna Poudwal, Ambikanandan Misra & Pravin Shende. (2021) Role of lipid nanocarriers for enhancing oral absorption and bioavailability of insulin and GLP-1 receptor agonists. Journal of Drug Targeting 29:8, pages 834-847.
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Bader B Alsulays, Md Khalid Anwer, Gamal A Soliman, Sultan M Alshehri & El-Sayed Khafagy. (2019) Impact Of Penetratin Stereochemistry On The Oral Bioavailability Of Insulin-Loaded Solid Lipid Nanoparticles. International Journal of Nanomedicine 14, pages 9127-9138.
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Daijun Zhou, Ruijia Yang, Tao Yang, Malcolm Xing & Gaoxing Luo. (2018) Preparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice. International Journal of Nanomedicine 13, pages 4157-4169.
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Lan Tang, Lulu Fu, Zhuanfeng Zhu, Yan Yang, Boxuan Sun, Weiguang Shan & Zhenhai Zhang. (2018) Modified mixed nanomicelles with collagen peptides enhanced oral absorption of Cucurbitacin B: preparation and evaluation. Drug Delivery 25:1, pages 862-871.
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Articles from other publishers (19)

Taoxing Peng, Xinyue Shao, Li Long, Han Liu, Wenqin Song, Jiazhen Hou, Haijun Zhong, Yang Ding & Yongzhuo Huang. (2023) Rational design of oral delivery nanosystems for hypoglycemic peptides. Nano Today 53, pages 102031.
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Alessandro Gori, Giulia Lodigiani, Stella G. Colombarolli, Greta Bergamaschi & Alberto Vitali. (2023) Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications. ChemMedChem 18:17.
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Monu Yadav, Milind Parle, Nidhi Sharma, Deepak Kumar Jindal, Kajal Joshi, Neha Raina & Tinku Gupta. (2023) Development and evaluation of loperamide hydrochloride loaded chitosan nanoformulation for neurotoxic effects on mice. Polymer Bulletin.
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Tao Zhou, Yushi Liu, Kelu Lei, Junjing Liu, Minghao Hu, Li Guo, Yiping Guo & Qiang Ye. (2023) A “Trojan Horse” Strategy: The Preparation of Bile Acid-Modifying Irinotecan Hydrochloride Nanoliposomes for Liver-Targeted Anticancer Drug Delivery System Study. Molecules 28:4, pages 1577.
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Ülo LangelÜlo Langel. 2023. CPP, Cell-Penetrating Peptides. CPP, Cell-Penetrating Peptides 469 541 .
Ülo LangelÜlo Langel. 2023. CPP, Cell-Penetrating Peptides. CPP, Cell-Penetrating Peptides 263 311 .
Myla Lôbo de Souza, Victor de Albuquerque Wanderley Sales, Larissa Pereira Alves, Widson Michael dos Santos, Leslie Raphael de Moura Ferraz, Gustavo Siqueira de Andrade Lima, Larissa Morgana dos Santos Mendes, Larissa Araújo Rolim & Pedro José Rolim Neto. (2022) A Systematic Review of Functionalized Polymeric Nanoparticles to Improve Intestinal Permeability of Drugs and Biological Products. Current Pharmaceutical Design 28:5, pages 410-426.
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Cristian Reboredo, Carlos J. González-Navarro, Ana Luisa Martínez-López, Cristina Martínez-Ohárriz, Bruno Sarmento & Juan M. Irache. (2021) Zein-Based Nanoparticles as Oral Carriers for Insulin Delivery. Pharmaceutics 14:1, pages 39.
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Agnieszka Piegat, Anna Żywicka, Agata Niemczyk & Agata Goszczyńska. (2020) Antibacterial Activity of N,O-Acylated Chitosan Derivative. Polymers 13:1, pages 107.
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Samira Sadeghi, Wai Kit Lee, Shik Nie Kong, Annanya Shetty & Chester Lee Drum. (2020) Oral administration of protein nanoparticles: An emerging route to disease treatment. Pharmacological Research 158, pages 104685.
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Shao-qing Chen, Yan-qing Song, Cheng Wang, Shan Tao, Fang-ying Yu, Hai-ya Lou, Fu-qiang Hu & Hong Yuan. (2020) Chitosan-modified lipid nanodrug delivery system for the targeted and responsive treatment of ulcerative colitis. Carbohydrate Polymers 230, pages 115613.
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Eman Saddar El Leithy, Hend Mohamed Abdel-Bar & Raghda Abdel-Moneum Ali. (2019) Folate-chitosan nanoparticles triggered insulin cellular uptake and improved in vivo hypoglycemic activity. International Journal of Pharmaceutics 571, pages 118708.
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Feng Guo, Ting Ouyang, Taoxing Peng, Xiuying Zhang, Baogang Xie, Xiaoling Yang, Desheng Liang & Haijun Zhong. (2019) Enhanced oral absorption of insulin using colon-specific nanoparticles co-modified with amphiphilic chitosan derivatives and cell-penetrating peptides. Biomaterials Science 7:4, pages 1493-1506.
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Suping Qiu, Desheng Liang, Feng Guo, Tiantian Deng, Taoxing Peng, Yuan Gao, Xiuying Zhang & Haijun Zhong. (2018) Solid lipid nanoparticles modified with amphipathic chitosan derivatives for improved stability in the gastrointestinal tract. Journal of Drug Delivery Science and Technology 48, pages 288-299.
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Mengjia Zhao, Sang Hoon Lee, Jae Geun Song, Hyeon Young Kim & Hyo-Kyung Han. (2018) Enhanced oral absorption of sorafenib via the layer-by-layer deposition of a pH-sensitive polymer and glycol chitosan on the liposome. International Journal of Pharmaceutics 544:1, pages 14-20.
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Canan Ozyurt, Ozge Ugurlu & Serap Evran. 2018. Nanostructures for the Engineering of Cells, Tissues and Organs. Nanostructures for the Engineering of Cells, Tissues and Organs 67 104 .
Francisca Araújo, José das Neves, João Pedro Martins, Pedro L. Granja, Hélder A. Santos & Bruno Sarmento. (2017) Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals. Progress in Materials Science 89, pages 306-344.
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Toshihiko Tashima. (2017) Intelligent substance delivery into cells using cell-penetrating peptides. Bioorganic & Medicinal Chemistry Letters 27:2, pages 121-130.
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Lei Lu, Gaoxian Chen, Yuanyuan Qiu, Mingwang Li, Dianhua Liu, Dehui Hu, Xiajing Gu & Zeyu Xiao. (2016) Nanoparticle-based oral delivery systems for colon targeting: principles and design strategies. Science Bulletin 61:9, pages 670-681.
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