Advanced search
Publication Cover
Drug Delivery Volume 23, 2016 - Issue 8
Submit an article Journal homepage
1,371
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Claudin-binder C-CPE mutants enhance permeability of insulin across human nasal epithelial cells

Takashi KojimaDepartment of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, Correspondence[email protected]
,
Masuo KondohLaboratory of Bio-Functional Molecular Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan,
,
Takashi KeiraDepartment of Otolaryngology and
,
Ken-ichi TakanoDepartment of Otolaryngology and
,
Takuya KakukiDepartment of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, ;Department of Otolaryngology and
,
Yakuto KanekoDepartment of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, ;Department of Otolaryngology and
,
Ryo MiyataDepartment of Otolaryngology and
,
Kazuaki NomuraDepartment of Otolaryngology and
,
Kazufumi ObataDepartment of Otolaryngology and
,
Takayuki KohnoDepartment of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan,
,
Takumi KonnoDepartment of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan,
,
Norimasa SawadaDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan
&
Tetsuo HimiDepartment of Otolaryngology and
show all
Pages 2703-2710 | Received 18 Mar 2015, Accepted 08 May 2015, Published online: 02 Jun 2015

Citations (14)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Rajiv Bajracharya, Jae Geun Song, Basavaraj Rudragouda Patil, Sang Hoon Lee, Hye-Mi Noh, Da-Hyun Kim, Gyu-Lin Kim, Soo-Hwa Seo, Ji-Won Park, Seong Hoon Jeong, Chang Hoon Lee & Hyo-Kyung Han. (2022) Functional ligands for improving anticancer drug therapy: current status and applications to drug delivery systems. Drug Delivery 29:1, pages 1959-1970.
Read now
Sam Maher, Caroline Geoghegan & David J. Brayden. (2021) Intestinal permeation enhancers to improve oral bioavailability of macromolecules: reasons for low efficacy in humans. Expert Opinion on Drug Delivery 18:2, pages 273-300.
Read now

Articles from other publishers (12)

Dan Luo, Xiaoqing Ni, Hao Yang, Lu Feng, Zhaoqun Chen & Lan Bai. (2024) A comprehensive review of advanced nasal delivery: Specially insulin and calcitonin. European Journal of Pharmaceutical Sciences 192, pages 106630.
Crossref
De-Wen Wang, Wei-Han Zhang, Galiullin Danil, Kun Yang & Jian-Kun Hu. (2022) The role and mechanism of claudins in cancer. Frontiers in Oncology 12.
Crossref
Archana Shrestha, Mauricio A. Navarro, Juliann Beingesser, Anibal G. Armien, Francisco A. Uzal & Bruce A. McClane. (2022) Characterizing the Contributions of Various Clostridium perfringens Enterotoxin Properties to In Vivo and In Vitro Permeability Effects . mSphere 7:5.
Crossref
Amita R. Banga, Peace Odiase, Kartik Rachakonda, Amar P. Garg, Samuel E. Adunyah & Girish Rachakonda. (2022) Application of C-Terminal Clostridium Perfringens Enterotoxin in Treatment of Brain Metastasis from Breast Cancer. Cancers 14:17, pages 4309.
Crossref
Andrew Lofts, Fahed Abu-Hijleh, Nicolette Rigg, Ram K. Mishra & Todd Hoare. (2022) Using the Intranasal Route to Administer Drugs to Treat Neurological and Psychiatric Illnesses: Rationale, Successes, and Future Needs. CNS Drugs 36:7, pages 739-770.
Crossref
Akihiro Watari, Miki Kodaka, Koji Matsuhisa, Yuta Sakamoto, Kota Hisaie, Norihito Kawashita, Tatsuya Takagi, Yoshiaki Yamagishi, Hidehiko Suzuki, Hirofumi Tsujino, Kiyohito Yagi & Masuo Kondoh. (2017) Identification of claudin-4 binder that attenuates tight junction barrier function by TR-FRET-based screening assay. Scientific Reports 7:1.
Crossref
Takashi Kojima, Takayuki Kohno, Terufumi Kubo, Yakuto Kaneko, Takuya Kakuki, Akito Kakiuchi, Makoto Kurose, Ken-ichi Takano, Noriko Ogasawara, Kazufumi Obata, Kazuaki Nomura, Ryo Miyata, Takumi Konno, Shingo Ichimiya & Tetsuo Himi. (2017) Regulation of claudin-4 via p63 in human epithelial cells. Annals of the New York Academy of Sciences 1405:1, pages 25-31.
Crossref
Yakuto Kaneko, Takayuki Kohno, Takuya Kakuki, Ken-ichi Takano, Noriko Ogasawara, Ryo Miyata, Shin Kikuchi, Takumi Konno, Tsuyoshi Ohkuni, Ryoto Yajima, Akito Kakiuchi, Shin-ichi Yokota, Tetsuo Himi & Takashi Kojima. (2017) The role of transcriptional factor p63 in regulation of epithelial barrier and ciliogenesis of human nasal epithelial cells. Scientific Reports 7:1.
Crossref
Yosuke Hashimoto, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi & Masuo Kondoh. (2017) Claudin‐targeted drug development using anti‐claudin monoclonal antibodies to treat hepatitis and cancer. Annals of the New York Academy of Sciences 1397:1, pages 5-16.
Crossref
M. Sánchez-Navarro, J. Garcia, E. Giralt & M. Teixidó. (2016) Using peptides to increase transport across the intestinal barrier. Advanced Drug Delivery Reviews 106, pages 355-366.
Crossref
Theodore G. Gabig, Wayne C. Waltzer, Terry Whyard & Victor Romanov. (2016) Clostridium perfringens enterotoxin as a potential drug for intravesical treatment of bladder cancer. Biochemical and Biophysical Research Communications 478:2, pages 887-892.
Crossref
John Freedman, Archana Shrestha & Bruce McClane. (2016) Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications. Toxins 8:3, pages 73.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.