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Drug Delivery Volume 23, 2016 - Issue 8
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Research Article

Utilization of ionotropic gelation technique for bioavailability enhancement of cinnarizine: in-vitro optimization and in-vivo performance in human

Samar M. AbouelattaDepartment of Pharmaceutics, Faculty of Pharmacy, Ahram Canadian University, Cairo, Egypt, Correspondence[email protected]
,
Ahmed A. AboelwafaDepartment of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt, and
,
Rawia M. KhalilNational Research Centre (NRC), Pharmaceutical Technology, Dokki, Cairo, Egypt
&
Omaima N. El-GazayerlyDepartment of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt, and
Pages 2736-2746 | Received 12 May 2015, Accepted 16 Jun 2015, Published online: 13 Jul 2015

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Samar M. Abouelatta, Ahmed A. Aboelwafa & Omaima N. El-Gazayerly. (2018) Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug. Drug Delivery 25:1, pages 1161-1174.
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Andrea Cerciello, Giulia Auriemma, Pasquale Del Gaudio, Marco Cantarini & Rita P. Aquino. (2016) Natural polysaccharides platforms for oral controlled release of ketoprofen lysine salt. Drug Development and Industrial Pharmacy 42:12, pages 2063-2069.
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Articles from other publishers (11)

Evgenia V. Blynskaya, Sergey V. Tishkov, Vladimir P. Vinogradov, Konstantin V. Alekseev, Anna I. Marakhova & Alexandre A. Vetcher. (2022) Polymeric Excipients in the Technology of Floating Drug Delivery Systems. Pharmaceutics 14:12, pages 2779.
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Hagar Ahmed Oransa, Mariza Fouad Boughdady & Hassan Mohamed EL-SabbaghSnrSnr. (2022) Novel Mucoadhesive Chitosomes as a Platform for Enhanced Oral Bioavailability of Cinnarizine. International Journal of Nanomedicine Volume 17, pages 5641-5660.
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Saige Meng, Shuangqing Wang & Ming Guan Piao. (2022) Prescription optimization of gastroretentive furosemide hollow-bioadhesive microspheres via Box-Behnken design: In vitro characterization and in vivo evaluation. Journal of Drug Delivery Science and Technology 70, pages 103235.
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Nieves Iglesias, Elsa Galbis, Lucía Romero-Azogil, Elena Benito, Ricardo Lucas, M. Gracia García-Martín & M.-Violante de-Paz. (2020) In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations. Pharmaceutics 12:7, pages 636.
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Hriday Bera, Sabyasachi Maiti, Sudipta Saha & Amit Kumar Nayak. 2019. Polysaccharide Carriers for Drug Delivery. Polysaccharide Carriers for Drug Delivery 713 736 .
Giulia Auriemma, Andrea Cerciello, Francesca Sansone, Aldo Pinto, Silvana Morello & Rita P. Aquino. (2018) Polysaccharides based gastroretentive system to sustain piroxicam release: Development and in vivo prolonged anti-inflammatory effect. International Journal of Biological Macromolecules 120, pages 2303-2312.
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Sheshank Sethi, Bhumika Mangla, Sunil Kamboj & Vikas Rana. (2018) A QbD approach for the fabrication of immediate and prolong buoyant cinnarizine tablet using polyacrylamide-g-corn fibre gum. International Journal of Biological Macromolecules 117, pages 350-361.
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Radhakrishnan Praveen, Priya Ranjan Prasad Verma, Jayachandran Venkatesan, Dong-Han Yoon, Se-Kwon Kim & Sandeep Kumar Singh. (2017) In vitro and in vivo evaluation of gastro-retentive carvedilol loaded chitosan beads using Gastroplus™. International Journal of Biological Macromolecules 102, pages 642-650.
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Mitulkumar A. Patel, Mohamed H.H. AbouGhaly, Jacqueline V. Schryer-Praga & Keith Chadwick. (2017) The effect of ionotropic gelation residence time on alginate cross-linking and properties. Carbohydrate Polymers 155, pages 362-371.
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Uttam Kumar Mandal, Bappaditya Chatterjee & Faria Gias Senjoti. (2016) Gastro-retentive drug delivery systems and their in vivo success: A recent update. Asian Journal of Pharmaceutical Sciences 11:5, pages 575-584.
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Hussein O. Ammar, Mahmoud Ghorab, Rabab Kamel & Alaa H. Salama. (2016) A trial for the design and optimization of pH-sensitive microparticles for intestinal delivery of cinnarizine. Drug Delivery and Translational Research 6:3, pages 195-209.
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