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Original Article

Microencapsulated Hepatocytes: an in Vitro and in Vivo Study

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Pages 483-496 | Published online: 11 Jul 2009

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Read on this site (8)

Laurence Canaple, Annemie Rehor & David Hunkeler. (2002) Improving cell encapsulation through size control . Journal of Biomaterials Science, Polymer Edition 13:7, pages 783-796.
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TM Rahman & HJF Hodgson. (2000) Artificial liver support - "bridge to transplantation?". Clinical Intensive Care 11:5, pages 227-237.
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Lisheng Wang, Junhong Sun, Li Li, Colin Harbour, Douglas Mears, Nick Koutalistras & Ag Ross Sheil. (2000) Factors Affecting Hepatocyte Viability and Cypial Activity During Encapsulation. Artificial Cells, Blood Substitutes, and Biotechnology 28:3, pages 215-227.
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N. P. Desai, A. Sojomihardjo, Z. Yao, N. Ron, P. Soon-Shiong. (2000) Interpenetrating polymer networks of alginate and polyethylene glycol for encapsulation of islets of Langerhans. Journal of Microencapsulation 17:6, pages 677-690.
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H Wong & Tms Chang. (1991) A Novel two Step Procedure for Immobilizing Living Cells in Microcapsules for Improving Xenograft Survival. Biomaterials, Artificial Cells and Immobilization Biotechnology 19:4, pages 687-697.
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Silvia Bruni & T. M. S. Chang. (1989) Hepatocytes Immobilised by Microencapsulation in Artificial Cells: Effects on Hyperbilirubihemia in Gunn Rats. Biomaterials, Artificial Cells and Artificial Organs 17:4, pages 403-411.
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. (1988) Literature Alerts. Journal of Microencapsulation 5:2, pages 177-202.
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Articles from other publishers (32)

Ogechi Ogoke, Janet Oluwole & Natesh Parashurama. (2017) Bioengineering considerations in liver regenerative medicine. Journal of Biological Engineering 11:1.
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Brend Ray-Sea Hsu & Shin-Huei Fu. 2017. Cell Microencapsulation. Cell Microencapsulation 57 70 .
Catherine Tomaro-Duchesneau, Shyamali Saha, Meenakshi Malhotra, Imen Kahouli & Satya Prakash. (2013) Microencapsulation for the Therapeutic Delivery of Drugs, Live Mammalian and Bacterial Cells, and Other Biopharmaceutics: Current Status and Future Directions. Journal of Pharmaceutics 2013, pages 1-19.
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Ying Ma, Ying Zhang, Yang Liu, Li Chen, Shen Li, Wei Zhao, Guangwei Sun, Na Li, Yu Wang, Xin Guo, Guojun Lv & Xiaojun Ma. (2013) Investigation of alginate-ϵ-poly- L -lysine microcapsules for cell microencapsulation . Journal of Biomedical Materials Research Part A 101A:5, pages 1265-1273.
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Thomas W. Link, Dian R. Arifin, Christopher M. Long, Piotr Walczak, Naser Muja, Aravind Arepally & Jeff W.M. Bulte. (2012) Use of Magnetocapsules for in Vivo Visualization and Enhanced Survival of Xenogeneic HepG2 Cell Transplants. Cell Medicine 4:2, pages 77-84.
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Liyuan Qiu, Jian Wang, Xinyu Wen, Haibin Wang, Yan Wang, Qiuxia Lin, Zhiyan Du, Cuimi Duan, Chunren Wang & Changyong Wang. (2012) Transplantation of Co-Microencapsulated Hepatocytes and HUVECs for Treatment of Fulminant Hepatic Failure. The International Journal of Artificial Organs 35:6, pages 458-465.
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Liang Haidong, Yu Fang, Tong Zhihong, Sun Huanwei & Zhang Tiehui. (2012) Use of combinations of gum arabic, maltodextrin and soybean protein to microencapsulate ginkgo leaf extracts and its inhibitory effect on skeletal muscle injury. Carbohydrate Polymers 88:2, pages 435-440.
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J. Matthias Löhr, Rainer Heuchel, Ralf Jesnowski & Christine Wallrapp. (2009) Therapy with Cell Encapsulation for Substitution of Organ Function and Tumor Treatment. Advanced Engineering Materials 11:8.
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Tim Maguire, Eric Novik, Rene Schloss & Martin Yarmush. (2006) Alginate‐PLL microencapsulation: Effect on the differentiation of embryonic stem cells into hepatocytes. Biotechnology and Bioengineering 93:3, pages 581-591.
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B. Zavan, P. Brun, V. Vindigni, A. Amadori, W. Habeler, P. Pontisso, D. Montemurro, G. Abatangelo & R. Cortivo. (2005) Extracellular matrix-enriched polymeric scaffolds as a substrate for hepatocyte cultures: in vitro and in vivo studies. Biomaterials 26:34, pages 7038-7045.
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T. Haque, H. Chen, W. Ouyang, C. Martoni, B. Lawuyi, A. Urbanska & S. Prakash. (2018) Investigation of a New Microcapsule Membrane Combining Alginate, Chitosan, Polyethylene Glycol and Poly-L-Lysine for Cell Transplantation Applications. The International Journal of Artificial Organs 28:6, pages 631-637.
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Tasima Haque, Hongmei Chen, Wei Ouyang, Christopher Martoni, Bisi Lawuyi, Aleksandra Malgorzata Urbanska & Satya Prakash. (2004) Superior Cell Delivery Features of Poly(ethylene glycol) Incorporated Alginate, Chitosan, and Poly- l -lysine Microcapsules . Molecular Pharmaceutics 2:1, pages 29-36.
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Jared W. AllenSangeeta N. Bhatia. (2002) Engineering Liver Therapies for the Future. Tissue Engineering 8:5, pages 725-737.
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MICHAEL DORNISH, DAVID KAPLAN & ØYVIND SKAUGRUD. (2006) Standards and Guidelines for Biopolymers in Tissue-Engineered Medical Products. Annals of the New York Academy of Sciences 944:1, pages 388-397.
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LAURENCE CANAPLE, NATHALIE NURDIN, NELA ANGELOVA, DAVID HUNKELER & BÉATRICE DESVERGNE. (2006) Development of a Coculture Model of Encapsulated Cells. Annals of the New York Academy of Sciences 944:1, pages 350-361.
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Laurence Canaple, Nathalie Nurdin, Nela Angelova, Damien Saugy, David Hunkeler & Béatrice Desvergne. (2001) Maintenance of primary murine hepatocyte functions in multicomponent polymer capsules – in vitro cryopreservation studies. Journal of Hepatology 34:1, pages 11-18.
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Marianne Khalil, Ali Shariat-Panahi, Rosemary Tootle, Tim Ryder, Paschal McCloskey, Eve Roberts, Humphrey Hodgson & Clare Selden. (2001) Human hepatocyte cell lines proliferating as cohesive spheroid colonies in alginate markedly upregulate both synthetic and detoxificatory liver function. Journal of Hepatology 34:1, pages 68-77.
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Stephan Schneider, Peter Johannes Feilen, Viola Slotty, Daniel Kampfner, Simon Preuss, Svend Berger, J?rgen Beyer & Rainer Pommersheim. (2001) Multilayer capsules: a promising microencapsulation system for transplantation of pancreatic islets. Biomaterials 22:14, pages 1961-1970.
Crossref
Taylor G. Wang & Robert P. Lanza. 2000. Principles of Tissue Engineering. Principles of Tissue Engineering 495 507 .
Rahman & Hodgson. (2001) Review article: liver support systems in acute hepatic failure. Alimentary Pharmacology & Therapeutics 13:10, pages 1255-1272.
Crossref
BENEDIKT BUSSE & JÖRG C. GERLACH. (2006) Bioreactors for Hybrid Liver Support: Historical Aspects and Novel Designs. Annals of the New York Academy of Sciences 875:1, pages 326-339.
Crossref
ANTHONY M. SUN. (2006) Microencapsulation of Cells. Annals of the New York Academy of Sciences 831:1, pages 271-279.
Crossref
Arye Lazar, Henry J. Mann, Rory P. Remmel, Russell A. Shatford, Frank B. Cerra & Wei-Shou Hu. (1995) Extended liver-specific functions of porcine hepatocyte spheroids entrapped in collagen gel. In Vitro Cellular & Developmental Biology - Animal 31:5, pages 340-346.
Crossref
Michael B. Yang, Joseph P. Vacanti & Donald E. Ingber. (2017) Hollow Fibers for Hepatocyte Encapsulation and Transplantation: Studies of Survival and Function in Rats. Cell Transplantation 3:5, pages 373-385.
Crossref
H.G. Koebe, M. Wick, U. Cramer, V. Lange & F.W. Schildberg. (2018) Collagen Gel Immobilisation Provides a Suitable Cell Matrix for Long Term Human Hepatocyte Cultures in Hybrid Reactors. The International Journal of Artificial Organs 17:2, pages 95-106.
Crossref
Kiyohito Yagi, Kozo Tsuda, Masashi Serada, Chikaomi Yamada, Akihiro Kondoh & Yoshiharu Miura. (2008) Rapid Formation of Multicellular Spheroids of Adult Rat Hepatocytes by Rotation Culture and Their Immobilization within Calcium Alginate. Artificial Organs 17:11, pages 929-934.
Crossref
Scott L. Nyberg, Madhusudan V. Peshwa, William D. Payne, Wei-Shou Hu & Frank B. Cerra. (1993) Evolution of the bioartificial liver: The need for randomized clinical trials. The American Journal of Surgery 166:5, pages 512-521.
Crossref
G.D.M. Wells, M.M. Fisher & M.V. Sefton. (1993) Microencapsulation of viable hepatocytes in HEMA-MMA microcapsules: a preliminary study. Biomaterials 14:8, pages 615-620.
Crossref
Michael V. Sefton & William T. K. Stevenson. 1993. Biopolymers I. Biopolymers I 143 197 .
S. Bruni & T.M.S. Chang. (2018) Encapsulated Hepatocytes for Controlling Hyperbilirubinemia in Gunn Rats. The International Journal of Artificial Organs 14:4, pages 239-241.
Crossref
Zhuhui Cai, Zhiqing Shi, Morris Sherman & Anthony M. Sun. (1989) Development and evaluation of a system of microencapsulation of primary rat hepatocytes. Hepatology 10:5, pages 855-860.
Crossref
Zhuhui Cai, Zhiqing Shi, M. Geraldine, O'Shea & Anthony M. Sun. (2008) Microencapsulated Hepatocytes for Bioartificial Liver Support. Artificial Organs 12:5, pages 388-393.
Crossref

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