Advanced search
Publication Cover
Biomaterials, Artificial Cells and Artificial Organs Volume 16, 1988 - Issue 1-3
Journal homepage
13
Views
28
CrossRef citations to date
0
Altmetric
Original Article

Hemoglobin: A Lifesaver and an Oxidant how to tip the Balance

Anne E. Faassen Dight Laboratories Dept. of Surgery, University of Minnesota, Minneapolis, MN, 55455
,
Steven R. Sundby Dight Laboratories Dept. of Surgery, University of Minnesota, Minneapolis, MN, 55455
,
S. Scott Panter Dight Laboratories Dept. of Surgery, University of Minnesota, Minneapolis, MN, 55455
,
Richard M Condie Dept. of Surgery, University of Minnesota, Minneapolis, MN, 55455
&
Bo E. Hedlund Dight Laboratories Dept. of Surgery, University of Minnesota, Minneapolis, MN, 55455
Pages 93-104 | Published online: 11 Jul 2009

Citations (28)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Sven Hungerer, Dirk Nolte, Andreas Botzlar & Konrad Messmer. (2006) Effects of Diaspirin Crosslinked Hemoglobin (DCLHb) on Microcirculation and Local Tissue PO2 of Striated Skin Muscle Following Resuscitation from Hemorrhagic Shock. Artificial Cells, Blood Substitutes, and Biotechnology 34:5, pages 455-471.
Read now
F. D'agnillo & T. M. S. Chang. (1997) Reduction of Hydroxyl Radical Generation in a Rat Hindlimb Model of Ischemia-Reperfusion Injury Using Crosslinked Hemoglobin-Superoxide Dismutase-Catalase. Artificial Cells, Blood Substitutes, and Biotechnology 25:1-2, pages 163-180.
Read now
Nelson Hsia & Johannes Everse. (1996) The Cytotoxic Activities of Human Hemoglobin and Diaspirin Crosslinked Hemoglobin. Artificial Cells, Blood Substitutes, and Biotechnology 24:5, pages 533-551.
Read now
J. Simoni, G. Simoni, E. L. Garcia, S. D. Prien, R. M. Tran, M. Feola & G. T. Shires. (1995) Protective Effect of Selenium on Hemoglobin Mediated Lipid Peroxidation in vivo. Artificial Cells, Blood Substitutes, and Biotechnology 23:4, pages 469-486.
Read now
A. I. Alayash, B. A. Brockner Ryan, J. C. Fratantoni & R. E. Cashon. (1994) Redox Reactivity of Modified Hemoglobins with Hydrogen Peroxide and Nitric Oxide: Toxicological Implications. Artificial Cells, Blood Substitutes, and Biotechnology 22:3, pages 373-386.
Read now
Thomas M. S. Chang. (1992) Blood Substitutes Based on Modified Hemoglobin Prepared by Encapsulation or Crosslinking: an Overview. Biomaterials, Artificial Cells and Immobilization Biotechnology 20:2-4, pages 159-179.
Read now
Jan Simoni, Mario Feola & Peter C. Canizaro. (1990) Generation of Free Oxygen Radicals and the Toxicity of Hemoglobin Solutions. Biomaterials, Artificial Cells and Artificial Organs 18:2, pages 189-202.
Read now
P. Menu, P. Labrude & C. Vigneron. (1990) Usual Physicochemical Criteria Provide Insufficient Evidence That a Functional Hemoglobin Solution can be Used for Transfusions After Storage for 36 Months at +4°c. Biomaterials, Artificial Cells and Artificial Organs 18:2, pages 169-181.
Read now

Articles from other publishers (20)

Jan Simoni, Grace Simoni & John F. Moeller. (2009) Intrinsic Toxicity of Hemoglobin: How to Counteract It. Artificial Organs 33:2, pages 100-109.
Crossref
M.A. Burmeister, C. Rempf, T.G. Standl, S. Rehberg, S. Bartsch-Zwemke, T. Krause, S. Tuszynski, A. Gottschalk & J. Schulte am Esch. (2005) Effects of prophylactic or therapeutic application of bovine haemoglobin HBOC-200 on ischaemia–reperfusion injury following acute coronary ligature in rats †. British Journal of Anaesthesia 95:6, pages 737-745.
Crossref
Jan Simoni. 2005. Artificial Oxygen Carrier. Artificial Oxygen Carrier 75 126 .
Jacques Creteur & Jean-Louis Vincent. (2003) Hemoglobin solutions. Critical Care Medicine 31:Supplement, pages S698-S707.
Crossref
Jean G. Riess. (2001) Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft . Chemical Reviews 101:9, pages 2797-2920.
Crossref
Jan Simoni, Grace Simoni, Donald E. Wesson, John A. Griswold & Mario Feola. (2000) A Novel Hemoglobin-Adenosine-Glutathione Based Blood Substitute: Evaluation of Its Effects on Human Blood Ex Vivo. ASAIO Journal 46:6, pages 679-692.
Crossref
Jacques Creteur, William Sibbald & Jean-Louis Vincent. (2000) Hemoglobin solutions—Not just red blood cell substitutes. Critical Care Medicine 28:8, pages 3025-3034.
Crossref
Felice D’Agnillo & Abdu I. Alayash. (2000) Site-specific modifications and toxicity of blood substitutes. Advanced Drug Delivery Reviews 40:3, pages 199-212.
Crossref
Sven Pickelmann, Dirk Nolte, Rosmarie Leiderer, Elke Schütze & Konrad Messmer. (1998) Attenuation of postischemic reperfusion injury in striated skin muscle by diaspirin-cross-linked Hb. American Journal of Physiology-Heart and Circulatory Physiology 275:2, pages H361-H368.
Crossref
David Whitley, Robert Patterson & A.Gerson Greenburg. (1998) Cell-Free Hemoglobin Preserves Renal Function during Normothermic Ischemia. Journal of Surgical Research 77:2, pages 187-191.
Crossref
Johannes Everse. (1998) The Structure of Heme Proteins Compounds I and II: Some Misconceptions. Free Radical Biology and Medicine 24:7-8, pages 1338-1346.
Crossref
T.M.S. Chang. 1998. Biotechnolgy Annual Review. Biotechnolgy Annual Review 75 112 .
John D. Klemperer & O. Wayne Isom. 1998. Blood Conservation in Cardiac Surgery. Blood Conservation in Cardiac Surgery 581 599 .
Wieslaw Kaca, Robert I. Roth, Kim D. Vandegriff, G. Chi Chen, Frans A. Kuypers, Robert M. Winslow & Jack Levin. (2002) Effects of Bacterial Endotoxin on Human Cross-Linked and Native Hemoglobins. Biochemistry 34:35, pages 11176-11185.
Crossref
G. Deby-Dupont, J. Pincemail & M. Lamy. 1994. Yearbook of Intensive Care and Emergency Medicine 1994. Yearbook of Intensive Care and Emergency Medicine 1994 264 275 .
Yoichi Osawa, John F. Darbyshire, Carl A. Meyer & Abdu I. Alayash. (1993) Differential susceptibilities of the prosthetic heme of hemoglobin-based red cell substitutes. Biochemical Pharmacology 46:12, pages 2299-2305.
Crossref
A.I. Alayash, B.A. Brockner Ryan & J.C. Fratantoni. (1993) Oxidation reactions of human, opossum (Didelphis virginiana) and spot (Leiostomus xanthurus) hemoglobins: a search for a correlation with some structural-functional properties. Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 106:2, pages 427-432.
Crossref
Abdu I. Alayash, Joseph C. Fratantoni, Celia Bonaventura, Joseph Bonaventura & Enrico Bucci. (1992) Consequences of chemical modifications on the free radical reactions of human hemoglobin. Archives of Biochemistry and Biophysics 298:1, pages 114-120.
Crossref
Kwang Nho, Samuel Zalipsky, Abraham Abuchowski & Frank F. Davis. 1992. Poly(Ethylene Glycol) Chemistry. Poly(Ethylene Glycol) Chemistry 171 182 .
Thomas M.S. Chang. (1989) The Use of Modified Hemoglobin as an Oxygen Carrying Blood Substitute. Transfusion Medicine Reviews 3:3, pages 213-218.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.