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Original Article

Mechanisms of Toxicity of Hemoglobin Solutions

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Pages 217-226 | Published online: 11 Jul 2009

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Read on this site (13)

Jan Simoni, Grace Simoni, Charles D. Lox, Samuel D. Prien, Rue Tran & Tom Shires. (1997) Expression of Adhesion Molecules and von Willebrand Factor in Human Coronary Artery Endothelial Cells Incubated with Differently Modified Hemoglobin Solutions. Artificial Cells, Blood Substitutes, and Biotechnology 25:1-2, pages 211-225.
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Gary Marchand, Elizabeth Dunlap, Liam Farrell, Carmen Nigro & Kenneth Burhop. (1996) Resuscitation with Increasing Doses of Diaspirin Crosslinked Hemoglobin in Swine. Artificial Cells, Blood Substitutes, and Biotechnology 24:5, pages 469-487.
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Janos Szebeni, Nabila M. Wassef, Alan S. Rudolph & Carl R. Alving. (1995) Complement Activation by Liposome-Encapsulated Hemoglobin In Vitro: The Role of Endotoxin Contamination. Artificial Cells, Blood Substitutes, and Biotechnology 23:3, pages 355-363.
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Robert F. Reiss, Ruben Caballero & John Hess. (1992) Effects of X-Linked Hemoglobin oph in-Vitro Platelet Function. Biomaterials, Artificial Cells and Immobilization Biotechnology 20:2-4, pages 651-655.
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T. M. S. Chang & C. Lister. (1992) A Preclinical Screening Test for Modified Hemoglobin to Bridge the Gap Between Animal Safety Studies and Use in Human. Biomaterials, Artificial Cells and Immobilization Biotechnology 20:2-4, pages 565-573.
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Kwang Nho, Donald Glower, Steven Bredehoeft, Hari Shankar, Robert Shorr & Abe Abuchowski. (1992) Peg-Bovine Hemoglobin: Safety en a Canine Dehydrated Hypovolemic-Hemorrhagic Shock Model. Biomaterials, Artificial Cells and Immobilization Biotechnology 20:2-4, pages 511-524.
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Thomas M. S. Chang. (1992) Blood Substitutes Based on Modified Hemoglobin Prepared by Encapsulation or Crosslinking: an Overview. Biomaterials, Artificial Cells and Immobilization Biotechnology 20:2-4, pages 159-179.
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T. Tsuchiya, H. Kawanishi, M. Sugiyama & F. Yoshimoto. (1990) Development of Selective Adsorbent for Free-Hemoglobin. Biomaterials, Artificial Cells and Artificial Organs 18:4, pages 471-475.
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T. M. S. Chang & C. Lister. (1990) A Screening Test for Modified Hemoglobin Blood Substitutes Before Clinical Use: Based on C3a Complement Activation in Human Plasma. Biomaterials, Artificial Cells and Artificial Organs 18:5, pages 693-701.
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Jing Ning & Thomas M.S Chang. (1990) Effects of Homologous and Heterologous Stroma-Free Hemoglobin and Polyhemoglobin on Complement Activation, Leucocytes and Platelets. Biomaterials, Artificial Cells and Artificial Organs 18:2, pages 219-232.
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Jing Ning & Thomas M.S Chang. (1990) Whole Complement Hemolytic Activity (Ch50) Following Infusion of Stroma-Free and Polyhemoglobin Solutions in Rats. Biomaterials, Artificial Cells and Artificial Organs 18:2, pages 203-217.
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Jan Simoni, Mario Feola & Peter C. Canizaro. (1990) Generation of Free Oxygen Radicals and the Toxicity of Hemoglobin Solutions. Biomaterials, Artificial Cells and Artificial Organs 18:2, pages 189-202.
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Articles from other publishers (25)

Jan Simoni. 2022. Blood Substitutes and Oxygen Biotherapeutics. Blood Substitutes and Oxygen Biotherapeutics 227 234 .
Auns Q Al-Neami, Noor S Shalal & Khawla H Rasheed. (2020) An artificial blood, electron microscope image, support, principles, benefits, and fusion methods: a review. IOP Conference Series: Materials Science and Engineering 870:1, pages 012019.
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G. Deby-Dupont, Bernadette Remy & Maurice Lamy. 2010. Alternatives to Blood Transfusion in Transfusion Medicine. Alternatives to Blood Transfusion in Transfusion Medicine 368 379 .
Y. Smani, P. Labrude, C. Vigneron & B. Faivre. (2007) Les transporteurs d’oxygène à base d’hémoglobine et les tentatives de substituer les globules rouges. Transfusion Clinique et Biologique 14:5, pages 464-473.
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Andrew D. Baines. 2006. Blood Substitutes. Blood Substitutes 217 226 .
Jan Simoni, Grace Simoni, Donald E. Wesson, John A. Griswold & Mario Feola. (2000) A Novel Hemoglobin-Adenosine-Glutathione Based Blood Substitute: Evaluation of Its Effects on Human Blood Ex Vivo. ASAIO Journal 46:6, pages 679-692.
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R. Sümpelmann, T. Schürholz, G. Marx & R. Zander. (2001) Protective effects of plasma replacement fluids on erythrocytes exposed to mechanical stress. Anaesthesia 55:10, pages 976-979.
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B. Rémy, G. Deby-Dupont, V. D'Ans, P. Ernest & M. Lamy. (1999) Substituts des globules rouges: émulsions de fluorocarbures et solutions d'hémoglobine. Annales Françaises d'Anesthésie et de Réanimation 18:2, pages 211-224.
Crossref
T.M.S. Chang. 1998. Biotechnolgy Annual Review. Biotechnolgy Annual Review 75 112 .
Alan S. Rudolph. 1998. Frontiers in Tissue Engineering. Frontiers in Tissue Engineering 481 494 .
Anil Gulati, Avadhesh C Sharma & Govind Singh. (1996) Role of endothelin in the cardiovascular effects of diaspirin crosslinked and stroma reduced hemoglobin. Critical Care Medicine 24:1, pages 137-147.
Crossref
Wieslaw Kaca, Robert I. Roth, Kim D. Vandegriff, G. Chi Chen, Frans A. Kuypers, Robert M. Winslow & Jack Levin. (2002) Effects of Bacterial Endotoxin on Human Cross-Linked and Native Hemoglobins. Biochemistry 34:35, pages 11176-11185.
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Juraj Sprung, Colin F. Mackenzie, George M. Barnas, John E. Williams, Michael Parr, Robert H. Christenson, Brian H. Hoff, Ronald Sakamoto, Andrew Kramer & Mark Lottes. (1995) Oxygen transport and cardiovascular effects of resuscitation from severe hemorrhagic shock using hemoglobin solutions. Critical Care Medicine 23:9, pages 1540-1553.
Crossref
J. Pincemail, O. Detry, C. Philippart, J.O. Defraigne, C. Franssen, K. Burhop, C. Deby, M. Meurisse & M. Lamy. (1995) Diaspirin crosslinked hemoglobin (DCLHbTM): Absence of increased free radical generation following administration in a rabbit model of renal ischemia and reperfusion. Free Radical Biology and Medicine 19:1, pages 1-9.
Crossref
Alan S. Rudolph, Helmut Spielberg, Barry J. Spargo & Nir Kossovsky. (2004) Histopathologic study following administration of liposome‐encapsulated hemoglobin in the normovolemic rat. Journal of Biomedical Materials Research 29:2, pages 189-196.
Crossref
Roel E. Reddingius, Cornelis H. Schröder, Hans L. Willems, Frans C.A. Van Den Brandt, Gerardus C.M. Koomen, Raymond T. Krediet & Leo A.H. Monnens. (2020) Measurement of Peritoneal Fluid Handling in Children on Continuous Ambulatory Peritoneal Dialysis Using Autologous Hemoglobin. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 14:1, pages 42-47.
Crossref
Jan Simoni, Grace Simoni & Mario Feola. (1993) Chromatographic analysis of biopolymers distribution in “poly-hemoglobin”, an intermolecularly crosslinked hemoglobin solution. Analytica Chimica Acta 279:1, pages 73-88.
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Jan Simoni, Grace Simoni & Mario Feola. 1993. Analytical Biotechnology. Analytical Biotechnology 73 88 .
Beverly A. Teicher, Terence S. Herman, Robert E. Hopkins & Krishna Menon. (1992) Effect of a bovine hemoglobin preparation on the response of the FSaIIC fibrosarcoma to chemotherapeutic alkylating agents. Journal of Cancer Research and Clinical Oncology 118:2, pages 123-128.
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Kwang Nho, Samuel Zalipsky, Abraham Abuchowski & Frank F. Davis. 1992. Poly(Ethylene Glycol) Chemistry. Poly(Ethylene Glycol) Chemistry 171 182 .
Nir Kossovsky & David Millett. (2013) Materials Biotechnology and Blood Substitutes. MRS Bulletin 16:9, pages 78-81.
Crossref
Beverly A. Teicher, Terence S. Herman, Robert E. Hopkins & Krishna Menon. (1991) Effect of oxygen level on the enhancement of tumor response to radiation by perfluorochemical emulsions or a bovine hemoglobin preparation. International Journal of Radiation Oncology*Biology*Physics 21:4, pages 969-974.
Crossref
Richard A. Bauman, Robert J. Przybelski & Marilyn J. Bounds. (1991) The effects of α-α cross-linked hemoglobin on the feeding and locomotor activity of rats. Physiology & Behavior 50:1, pages 205-211.
Crossref
J. Ning & T.M.S. Chang. (2018) In Vivo Effects of Stroma-Free Hemoglobin and Polyhemoglobin on Coagulation Factors in Rats. The International Journal of Artificial Organs 13:8, pages 509-516.
Crossref
Thomas M.S. Chang. (1989) The Use of Modified Hemoglobin as an Oxygen Carrying Blood Substitute. Transfusion Medicine Reviews 3:3, pages 213-218.
Crossref

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