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Original Article

Overview of Progress in the Fluorocarbon Approach to in vivo Oxygen Delivery

Pages 183-202 | Published online: 11 Jul 2009

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Read on this site (7)

C.D. Thomas, M. Prade & M. Guichard. (1995) Tumour Oxygenation, Radiosensitivity, and Necrosis before and/or after Nicotinamide, Carbogen and Perflubron Emulsion Administration. International Journal of Radiation Biology 67:5, pages 597-605.
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A. J. McGoron, R. Pratt, J. Zhang, Y. Shiferaw, S. Thomas & R. Millard. (1994) Perfluorocarbon Distribution to Liver, Lung and Spleen of Emulsions of Perfluorotributylamine (FTBA) in Pigs and Rats and Perfluorooctyl Bromide (Pfob) in Rats and Dogs by 19F NMR Spectroscopy. Artificial Cells, Blood Substitutes, and Biotechnology 22:4, pages 1243-1250.
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L. Zarif, M. Postel, L. Trevino, J. G. Riess, A. Valla & R. Follana. (1994) Biodistribution and Excretion of a Mixed Fluorocarbon-Hydrocarbon “Dowel” Emulsion as Determined by 19F NMR. Artificial Cells, Blood Substitutes, and Biotechnology 22:4, pages 1193-1198.
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C. Cornélus, M. P. Krafft & J. G. Riess. (1994) Improved Control over Particle Sizes and Stability of Concentrated Fluorocarbon Emulsions by Using Mixed Fluorocarbon/Hydrocarbon Molecular Dowels. Artificial Cells, Blood Substitutes, and Biotechnology 22:4, pages 1183-1191.
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R. P. Mason. (1994) Non-Invasive Physiology: 19F NMR of Perfluorocarbons. Artificial Cells, Blood Substitutes, and Biotechnology 22:4, pages 1141-1153.
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M. Postel, J. G. Riess & J. G. Weers. (1994) Fluorocarbon Emulsions the Stability Issue. Artificial Cells, Blood Substitutes, and Biotechnology 22:4, pages 991-1005.
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Leo Trevino, Frédéric Frézard, Michèle Postel & Jean G. Riess. (1994) Incorporation of a perfluoroalkylalkane (RFRH) into the phospholipid bilayer of dmpc liposomes results in greater encapsulation stability. Journal of Liposome Research 4:2, pages 1017-1028.
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Deepthi Alapati & Thomas H. Shaffer. (2022) Administration of Drugs/Gene Products to the Respiratory System: A Historical Perspective of the Use of Inert Liquids. Frontiers in Physiology 13.
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Sebastian Temme, Mina Yakoub, Pascal Bouvain, Guang Yang, Jürgen Schrader, Johannes Stegbauer & Ulrich Flögel. (2021) Beyond Vessel Diameters: Non-invasive Monitoring of Flow Patterns and Immune Cell Recruitment in Murine Abdominal Aortic Disorders by Multiparametric MRI. Frontiers in Cardiovascular Medicine 8.
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Roberto Colotti, Jessica A. M. Bastiaansen, Anne Wilson, Ulrich Flögel, Christine Gonzales, Juerg Schwitter, Matthias Stuber & Ruud B. van Heeswijk. (2017) Characterization of perfluorocarbon relaxation times and their influence on the optimization of fluorine-19 MRI at 3 tesla. Magnetic Resonance in Medicine 77:6, pages 2263-2271.
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Martijn Wolters, Seyede G. Mohades, Tilman M. Hackeng, Mark J. Post, Marianne E. Kooi & Walter H. Backes. (2013) Clinical Perspectives of Hybrid Proton-Fluorine Magnetic Resonance Imaging and Spectroscopy. Investigative Radiology 48:5, pages 341-350.
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Jong-Hoon Kim & Ki-Young Lee. (2009) Current Status and Future of Artificial Blood - Focusing on Red Blood Cell Substitutes. Journal of the Korean Medical Association 52:2, pages 168.
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Roman Kocian & Donat R. Spahn. (2008) Haemoglobin, oxygen carriers and perioperative organ perfusion. Best Practice & Research Clinical Anaesthesiology 22:1, pages 63-80.
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Jian‐Xin Yu, Weina Cui, Dawen Zhao & Ralph P. Mason. 2008. Fluorine and Health. Fluorine and Health 197 276 .
PEDRO CABRALES & JOEL M. FRIEDMAN. (2007) Pegylated hemoglobins mechanisms to avoid vasoconstriction and maintain perfusion. Transfusion Alternatives in Transfusion Medicine 9:4, pages 281-293.
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Hiromi Sakai & Eishun Tsuchida. 2006. Wiley Encyclopedia of Biomedical Engineering. Wiley Encyclopedia of Biomedical Engineering.
Vikram D. Kodibagkar, Weina Cui, Matthew E. Merritt & Ralph P. Mason. (2006) Novel 1 H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane . Magnetic Resonance in Medicine 55:4, pages 743-748.
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Dawen Zhao, Lan Jiang & Ralph P. Mason. 2004. Imaging in Biological Research, Part B. Imaging in Biological Research, Part B 378 418 .
Thomas H. Shaffer & Marla R. Wolfson. 2004. Fetal and Neonatal Physiology. Fetal and Neonatal Physiology 985 1001 .
Steven E. Hill, Bruce J. Leone, N.Simon Faithfull, Kathy E. Flaim, Peter E. Keipert & Mark F. Newman. (2002) Perflubron emulsion (AF0144) augments harvesting of autologous blood: A phase II study in cardiac surgery. Journal of Cardiothoracic and Vascular Anesthesia 16:5, pages 555-560.
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Cynthia A. Cox, William W. Fox, Carla M. Weiss, Marla R. Wolfson & Thomas H. Shaffer. (2002) Liquid ventilation: Gas exchange, perfluorochemical uptake, and biodistribution in an acute lung injury. Pediatric Critical Care Medicine 3:3, pages 288-296.
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Bachir Khalfoun, Didier Barrat, Hervé Watier, Marie Christine Machet, Brigitte Arbeille-Brassart, Jean G. Riess, Henri Salmon, Yves Gruel, Pierre Bardos & Yvon Lebranchu. (2000) Development of an ex vivo model of pig kidney perfused with human lymphocytes. Analysis of xenogeneic cellular reactions. Surgery 128:3, pages 447-457.
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Donat R Spahn. (2000) Current status of artificial oxygen carriers. Advanced Drug Delivery Reviews 40:3, pages 143-151.
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D. R. Spahn. 2000. Yearbook of Intensive Care and Emergency Medicine 2000. Yearbook of Intensive Care and Emergency Medicine 2000 507 518 .
Thomas D. Roper, Paul E. Friedrich, Thomas Gees, William J. Lackey, Catherine Mader, Pierre Vierling & Catherine Santaella. (1998) An Efficient and Scalable Synthesis of Perfluorinated Phosphatidylcholines. Organic Process Research & Development 3:1, pages 67-70.
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D. De Vleeschauwer & P. Van der Meeren. (1998) A dynamic light scattering study of the influence of the phospholipid concentration in a model perfluorocarbon emulsion. Colloids and Surfaces B: Biointerfaces 11:6, pages 321-329.
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Robert L Stavis, Marla R Wolfson, Cynthia Cox, Nancy Kechner & Thomas H Shaffer. (1998) Physiologic, Biochemical, and Histologic Correlates Associated with Tidal Liquid Ventilation. Pediatric Research 43:1, pages 132-138.
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B. P. Wagner, R. Stingele, M. A. Williams, D. A. Wilson, R. J. Traystman & D. F. Hanley. (1997) NO contributes to neurohypophysial but not other regional cerebral fluorocarbon-induced hyperemia in cats. American Journal of Physiology-Heart and Circulatory Physiology 273:4, pages H1994-H2000.
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Alejandro M. Granados, Gerardo D. Fidelio & Rita H. de Rossi. (1997) Surface and Aggregation Properties of N -(4-Nitrophenyl)perfluorononanamide . Langmuir 13:15, pages 4079-4084.
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Stephen R. Thomas, Ronald G. Pratt, Ronald W. Millard, Ranasinghage C. Samaratunga, Yoseph Shiferaw, Anthony J. McGoron & Kim Kiat Tan. (1996) In vivo pO2 imaging in the porcine model with perfluorocarbon F-19 NMR at low field. Magnetic Resonance Imaging 14:1, pages 103-114.
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Susan A. Stern, Steven C. Dronen, Anthony J. McGoron, Xu Wang, Karen Chaffins, Ronald Millard, P.E. Keipert & N.S. Faithfull. (1995) Effect of supplemental perfluorocarbon administration on hypotensive resuscitation of severe uncontrolled hemorrhage. The American Journal of Emergency Medicine 13:3, pages 269-275.
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Thomas A. Lane. (1995) Perfluorochemical-based artificial oxygen carrying red cell substitutes. Transfusion Science 16:1, pages 19-31.
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Stephen R. Thomas, Ronald G. Pratt, Ronald W. Millard, R. C. Samaratunga, Yoseph Shiferaw, Leland C. ClarkJrJr & Richard E. Hoffmann. (2005) Evaluation of the influence of the aqueous phase bioconstituent environment on the F‐19 T1 of perfluorocarbon blood substitute emulsions. Journal of Magnetic Resonance Imaging 4:4, pages 631-635.
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