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Artificial Cells, Blood Substitutes, and Biotechnology Volume 22, 1994 - Issue 2
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Original Article

Heme and the Vasculature: an Oxidative Hazard that Induces Antioxidant Defenses in the Endothelium

G. M. Vercellotti Department of Medicine, Division of Hematology, University of Minnesota, Minneapolis, Minnesota, 55455
,
G. Balla Department of Pediatrics, University of Debrecen, Debrecen, Hungary
,
J. Balla Department of Medicine, Division of Hematology, University of Minnesota, Minneapolis, Minnesota, 55455
,
K. Nath Department of Medicine, Division of Renal Medicine, University of Minnesota, Minneapolis, Minnesota, 55455
,
J. W. Eaton Department of Pathology and Laboratory, Medicine Albany Medical College, Albany, New York
&
H. S. Jacob Department of Medicine, Division of Hematology, University of Minnesota, Minneapolis, Minnesota, 55455
Pages 207-213 | Published online: 11 Jul 2009

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Vibhudutta Awasthi, Vivek R. Yadav, Beth Goins & William T. Phillips. (2013) Modulation of oxidative stability of haemoglobin inside liposome-encapsulated haemoglobin. Journal of Microencapsulation 30:5, pages 471-478.
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Savcioglu Feyza, Akpinar Deniz, Yargicoglu Piraye & Agar Aysel. (2009) The Effect of Heme Oxygenase Inhibition on Visual Evoked Potentials. International Journal of Neuroscience 119:9, pages 1384-1398.
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Joannes J.M. Marx, Apriliana E.R. Kartikasari & Niki A. Georgiou. (2008) Can Iron Chelators Influence the Progression of Atherosclerosis?. Hemoglobin 32:1-2, pages 123-134.
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S-K. Lim. (2001) Consequences of haemolysis without haptoglobin. Redox Report 6:6, pages 375-378.
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S-K. Lim, B. Ferraro, K. Moore & B. Halliwell. (2001) Role of haptoglobin in free hemoglobin metabolism. Redox Report 6:4, pages 219-227.
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A A Shahin, R F Tamburro & J E Schmidt. (2000) Carboxyhemoglobin in pediatric sepsis and the systemic inflammatory response syndrome. Clinical Intensive Care 11:6, pages 311-317.
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Thomas F. Zuck, Jean G. Riess & G. P. Biro. (1994) Current Status of Injectable Oxygen Carriers. Critical Reviews in Clinical Laboratory Sciences 31:4, pages 295-324.
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Valentina Marassi, Stefano Giordani, Pierluigi Reschiglian, Barbara Roda & Andrea Zattoni. (2022) Tracking Heme-Protein Interactions in Healthy and Pathological Human Serum in Native Conditions by Miniaturized FFF-Multidetection. Applied Sciences 12:13, pages 6762.
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Stefan W. Ryter. (2022) Heme Oxygenase-1: An Anti-Inflammatory Effector in Cardiovascular, Lung, and Related Metabolic Disorders. Antioxidants 11:3, pages 555.
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Stefan W. Ryter. (2021) Significance of Heme and Heme Degradation in the Pathogenesis of Acute Lung and Inflammatory Disorders. International Journal of Molecular Sciences 22:11, pages 5509.
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Ian G. Chambers, Mathilda M. Willoughby, Iqbal Hamza & Amit R. Reddi. (2021) One ring to bring them all and in the darkness bind them: The trafficking of heme without deliverers. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:1, pages 118881.
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Kristof Van Avondt, Erfan Nur & Sacha Zeerleder. (2019) Mechanisms of haemolysis-induced kidney injury. Nature Reviews Nephrology 15:11, pages 671-692.
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L. Y. Liu, N. McGregor, B. K. J. Wong, H. Butt & I. B. Darby. (2016) The association between clinical periodontal parameters and free haem concentration within the gingival crevicular fluid: a pilot study. Journal of Periodontal Research 51:1, pages 86-94.
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Deborah Chiabrando, Francesca Vinchi, Veronica Fiorito, Sonia Mercurio & Emanuela Tolosano. (2014) Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes. Frontiers in Pharmacology 5.
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Richard A. Zager, Anitha Vijayan & Ali C. M. Johnson. (2012) Proximal tubule haptoglobin gene activation is an integral component of the acute kidney injury “stress response”. American Journal of Physiology-Renal Physiology 303:1, pages F139-F148.
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