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Original Article

Assessment of Hemoglobin-Dependent Neurotoxicity: Alpha-Alpha Crosslinked Hemoglobin

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Pages 399-413 | Published online: 11 Jul 2009

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Timothy N. Estep. (2015) Pharmacokinetics and mechanisms of plasma removal of hemoglobin-based oxygen carriers. Artificial Cells, Nanomedicine, and Biotechnology 43:3, pages 203-215.
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J. R. Hess. (1995) Review of Modified Hemoglobin Research at Letterman: Attempts to Delineate the Toxicity of Cell-Free Tetrameric Hemoglobin. Artificial Cells, Blood Substitutes, and Biotechnology 23:3, pages 277-289.
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Articles from other publishers (17)

Ian Galea, Soham Bandyopadhyay, Diederik Bulters, Rok Humar, Michael Hugelshofer, Dominik J. Schaer, Amr Abdulazim, Andrew F. Alalade, Sheila A. Alexander, Sergi Amaro, Sepideh Amin-Hanjani, Christopher R. Andersen, Craig Anderson, Matthew H. Anstey, József Balla, Nourou Dine Adeniran Bankole, Judith Bellapart, Hemant Bhagat, Spiros L. Blackburn, Markus Brechmann, ; Paul W. Buehler, Jan-Karl Burkhardt, Yujie Chen, Jeremy Cohen, P. David Cooper, Liam G. Coulthard, Elisa Cuadrado-Godia, Joan Dalton, Anthony Delaney, Sylvain Doré, Jonathan Downer, Justin Dye, Isabel Fernandez-Perez, Oliver Flower, Béla Fülesdi, Ben Gaastra, Thomas Gaberel, James Galea, Gbetoho Fortuné Gankpe, Patrick Garland, Thomas Gentinetta, Magnus Gram, Jonas Heilskov Graversen, Patrick J. Grover, Daniel Guisado-Alonso, David Hasan, Adel Helmy, Julius Höhne, Isabel Charlotte Hostettler, Ajay Prasad Hrishi, Koji Iihara, David C. Irwin, Kiran Jangra, Aruma Jiménez-O’Shanahan, Richard F. Keep, Matthew Koch, Miikka Korja, Munish Kumar, Laura Llull, James JM Loan, Miguel Ángel Lopez-Gonzalez, R. Loch Macdonald, Shalvi Mahajan, Joan Martí-Fàbregas, Jose Medina-Suárez, Soren Moestrup, John More, Eghosa Morgan, Radhakrishnan Muthuchellappan, Paul Nyquist, Coralia Sosa Pérez, Promod Pillai, Nikolaus Plesnila, Jose Javier Provencio, Eamon Raith, Anna Ramos-Pachón, Scott B. Raymond, Luca Regli, Ynte Marije Ruigrok, Poonam Saharan, Edgar A. Samaniego, Gerrit Alexander Schubert, Ian Seppelt, Kamath Sriganesh, Jose I. Suarez, Jonathon Taylor, Nicole A. Terpolilli, Fernando D. Testai, Emanuela Tolosano, Ahmed K. Toma, Anderson Chun On Tsang, Andrew A. Udy, Florence Vallelian, Mariana Vargas-Caballero, Gregory M Vercellotti, Mervyn D.I. Vergouwen, Michaela Waak, Hannah Warming, Peter C. Whitfield, George Kwok-chu Wong, Jason Wright & Adrian W. Zuercher. (2023) Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation. Stroke 54:7, pages 1930-1942.
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Toby A. Silverman & Richard B. Weiskopf. (2009) Hemoglobin-based oxygen carriers: current status and future directions. Transfusion 49:11, pages 2495-2515.
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Jan Simoni, Grace Simoni & John F. Moeller. (2009) Intrinsic Toxicity of Hemoglobin: How to Counteract It. Artificial Organs 33:2, pages 100-109.
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Guy Rosenthal, Diane Morabito, Mitchell Cohen, Annina Roeytenberg, Nikita Derugin, S. Scott Panter, M. Margaret Knudson & Geoffrey Manley. (2008) Use of hemoglobin-based oxygen-carrying solution–201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage. Journal of Neurosurgery 108:3, pages 575-587.
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Dominik J. SchaerChristian A. SchaerPaul W. BuehlerRobert A. BoykinsGabriele SchoedonAbdu I. AlayashAndreas Schaffner. (2006) CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin. Blood 107:1, pages 373-380.
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Robert M. Winslow. 2006. Blood Substitutes. Blood Substitutes 386 398 .
S. Scott Panter, Barbara L. Ellington & Raymond F. Regan. 2006. Blood Substitutes. Blood Substitutes 227 234 .
Jan Simoni. 2005. Artificial Oxygen Carrier. Artificial Oxygen Carrier 75 126 .
Paul W. Buehler & Abdu I. Alayash. (2004) Toxicities of hemoglobin solutions: in search of in-vitro and in-vivo model systems. Transfusion 44:10, pages 1516-1530.
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Jean G. Riess. (2001) Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft . Chemical Reviews 101:9, pages 2797-2920.
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Robert M. Winslow. (2000) alphaalpha-Crosslinked Hemoglobin: Was Failure Predicted by Preclinical Testing?. Vox Sanguinis 79:1, pages 1-20.
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Felice D’Agnillo, Francine Wood, Carlos Porras, Victor W. Macdonald & Abdu I. Alayash. (2000) Effects of hypoxia and glutathione depletion on hemoglobin- and myoglobin-mediated oxidative stress toward endothelium1The opinions and assertions contained herein are the scientific views of the authors and are not to be construed as policy of the United States Food and Drug Administration or the United States Army.1. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1495:2, pages 150-159.
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Laurie L. McLeod & Abdu I. Alayash. (1999) Detection of a ferrylhemoglobin intermediate in an endothelial cell model after hypoxia-reoxygenation. American Journal of Physiology-Heart and Circulatory Physiology 277:1, pages H92-H99.
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E Gene Deune & Susan E Mackinnon. (1998) Postoperative Drainage Is Recommended in Ulnar Nerve Transposition. Canadian Journal of Plastic Surgery 6:4, pages 201-203.
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Daniel W. Goldman, Richard J. BreyerIIIIII, David Yeh, Beth A. Brockner-Ryan & Abdu I. Alayash. (1998) Acellular hemoglobin-mediated oxidative stress toward endothelium: a role for ferryl iron. American Journal of Physiology-Heart and Circulatory Physiology 275:3, pages H1046-H1053.
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Ronald J. Rohlfs & Kim D. Vandegriff. 1996. Blood Substitutes. Blood Substitutes 163 184 .
Kim D. Vandegriff. 1995. Blood Substitutes. Blood Substitutes 105 131 .

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