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Artificial Cells, Blood Substitutes, and Biotechnology Volume 22, 1994 - Issue 3
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Original Article

Methemoglobin Formation After Administration of Hemoglobin Conjugated to Carboxylate Dextran in Guinea Pigs. Attempts to Prevent the Oxidation of Hemoglobin

B. Faivre Faculté de Pharmacie, 54001, Nancy Cedex, France
,
P. Menu Faculté de Pharmacie, 54001, Nancy Cedex, France
,
P Labrude Faculté de Pharmacie, 54001, Nancy Cedex, France
,
M. Grandgeorge Pasteur Mérieux Sérums & Vaccins, 69280, Marcy l'Etoile Cedex, France
&
C. Vigneron Faculté de Pharmacie, 54001, Nancy Cedex, France; Centre de Transfusion Sanguine, 54511, Vandoeuvre-lès-Nancy Cedex, France
Pages 551-558 | Published online: 11 Jul 2009

Citations (16)

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Read on this site (4)

Timothy N. Estep. (2015) Pharmacokinetics and mechanisms of plasma removal of hemoglobin-based oxygen carriers. Artificial Cells, Nanomedicine, and Biotechnology 43:3, pages 203-215.
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Abdu I Alayash, Felice D’Agnillo & Paul W Buehler. (2007) First-generation blood substitutes: what have we learned? Biochemical and physiological perspectives. Expert Opinion on Biological Therapy 7:5, pages 665-675.
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Xue Ying He, Bo Guan, Xiao Wei Zhang, Ke Xu, Yong Hai Yu, Qian Liu & Jian Shi Bai. (2007) Polyethylene Glycol Conjugated Bovine Hemoglobin Containing 15% MetHb Plays Approving Effect in Exchange Transfusion Rabbit Model. Artificial Cells, Blood Substitutes, and Biotechnology 35:5, pages 490-506.
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Béatrice Faivre, Patrick Menu, Pierre Labrude & Claude Vigneron. (1998) Hemoglobin Autooxidation/Oxidation Mechanisms and Methemoglobin Prevention or Reduction Processes in the Bloodstream Literature review and outline of autooxidation reaction. Artificial Cells, Blood Substitutes, and Biotechnology 26:1, pages 17-26.
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Articles from other publishers (12)

Aizhou Wang, Serena Singh, Binglan Yu, Donald B. Bloch, Warren M. Zapol & Ronald Kluger. (2018) Cross‐linked hemoglobin bis‐tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation. Transfusion 59:1, pages 359-370.
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Caroline Gaucher, Élisa Domingues-Hamdi, Christine Prin-Mathieu, Patrick Menu & Véronique Baudin-Creuza. (2015) Interaction of recombinant octameric hemoglobin with endothelial cells. Comptes Rendus Biologies 338:2, pages 95-102.
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Dong Wang, Barbora Piknova, Steven B. Solomon, Irene Cortes-Puch, Steven J. Kern, Junfeng Sun, Tamir Kanias, Mark T. Gladwin, Christine Helms, Daniel B. Kim-Shapiro, Alan N. Schechter & Charles Natanson. (2013) In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines. Transfusion 53:12, pages 3149-3163.
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Felice D’Agnillo. 2013. Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics. Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics 665 682 .
Claude Vigneron, Younes Smani & Béatrice Faivre. (2007) Les substituts érythrocytaires : état de l’art et raisons d’un espoir retardé. Bulletin de l'Académie Nationale de Médecine 191:4-5, pages 837-847.
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Felice D’Agnillo. 2006. Blood Substitutes. Blood Substitutes 206 216 .
Paul W. BuehlerAbdu I. Alayash. (2005) Redox Biology of Blood Revisited: The Role of Red Blood Cells in Maintaining Circulatory Reductive Capacity. Antioxidants & Redox Signaling 7:11-12, pages 1755-1760.
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Yiping Jia, Francine Wood, Patrick Menu, Béatrice Faivre, Alexis Caron & Abdu I Alayash. (2004) Oxygen binding and oxidation reactions of human hemoglobin conjugated to carboxylate dextran. Biochimica et Biophysica Acta (BBA) - General Subjects 1672:3, pages 164-173.
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M. Toussaint-Hacquard, Y. Devaux, D. Longrois, B. Faivre-Fiorina, S. Muller, J.F. Stoltz, C. Vigneron & P. Menu. (2003) Biological response of human aortic endothelial cells exposed to acellular hemoglobin solutions developed as potential blood substitutes. Life Sciences 72:10, pages 1143-1157.
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Jean G. Riess. (2001) Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft . Chemical Reviews 101:9, pages 2797-2920.
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Felice D’Agnillo & Abdu I. Alayash. (2000) Site-specific modifications and toxicity of blood substitutes. Advanced Drug Delivery Reviews 40:3, pages 199-212.
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Béatrice Faivre-Fiorina, Alexis Caron, Céline Fassot, Isabelle Fries, Patrick Menu, Pierre Labrude & Claude Vigneron. (1999) Presence of hemoglobin inside aortic endothelial cells after cell-free hemoglobin administration in guinea pigs. American Journal of Physiology-Heart and Circulatory Physiology 276:2, pages H766-H770.
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