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Artificial Cells, Blood Substitutes, and Biotechnology Volume 25, 1997 - Issue 4
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Original Article

The Oxygen Carrying Capability of Hemoglobin Vesicles Evaluated in Rat Exchange Transfusion Models

K. Kobayashi Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
,
Y. Izumi Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
,
Aame Yoshizu Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
,
H. Horinouchi Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
,
S.I. Park Department of Polymer Chemistry, Advanced Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
,
H. Sakai Department of Polymer Chemistry, Advanced Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
,
S. Takeoka. Department of Polymer Chemistry, Advanced Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
,
H. Nishide Department of Polymer Chemistry, Advanced Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
&
E. Tsuchida Department of Polymer Chemistry, Advanced Research Institute for Science and Engineering, Waseda University, Tokyo, Japan
 show all
Pages 357-366 | Published online: 11 Jul 2009

Citations (17)

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Read on this site (2)

Eishun Tsuchida, Hiromi Sakai, Hirohisa Horinouchi & Koichi Kobayashi. (2006) Hemoglobin-Vesicles as a Transfusion Alternative. Artificial Cells, Blood Substitutes, and Biotechnology 34:6, pages 581-588.
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Stefan Guth, Stephanie Dinkelmann, Ulrike Domack, Harald Pätzschke & Wolfgang Karl Richard Barnikol. (2000) A Model of Stepwise Isovolaemic Blood Exchange in Anaesthetised, Spontaneously Breathing Rats to Evaluate the Oxygen Transport Efficiency of Artificial Oxygen Carriers. Artificial Cells, Blood Substitutes, and Biotechnology 28:2, pages 113-127.
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Articles from other publishers (15)

Anna Wrobeln, Johannes Jägers, Theresa Quinting, Timm Schreiber, Michael Kirsch, Joachim Fandrey & Katja B. Ferenz. (2020) Albumin-derived perfluorocarbon-based artificial oxygen carriers can avoid hypoxic tissue damage in massive hemodilution. Scientific Reports 10:1.
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Yuka Saito, Yasutomo Suzuki, Yoshitaka Yamanashi, Katsuyuki Terajima, Atsuhiro Sakamoto & Yukihiro Kondo. (2013) The impact on renal function of fluid resuscitation with hemoglobin vesicle solution in moderate hemorrhagic shock. Journal of Artificial Organs 16:3, pages 376-381.
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Thomas Ming Swi Chang. 2013. Biomaterials Science. Biomaterials Science 811 827 .
Valérie Centis, Pierre Proulx & Patrick Vermette. (2011) PEGylated liposomes encapsulating human hemoglobin enhance oxygen transfer and cell proliferation while decreasing cell hypoxia in fibrin. Biochemical Engineering Journal 55:3, pages 162-168.
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Hiromi Sakai, Michiko Okamoto, Eiji Ikeda, Hirohisa Horinouchi, Koichi Kobayashi & Eishun Tsuchida. (2008) Histopathological changes of rat brain after direct injection of Hb‐vesicles (artificial oxygen carriers) and neurological impact in an intracerebral hemorrhage model. Journal of Biomedical Materials Research Part A 90A:4, pages 1107-1119.
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Hiromi Sakai, Keitaro Sou, Shinji Takeoka, Koichi Kobayashi & Eishun Tsuchida. 2006. Blood Substitutes. Blood Substitutes 514 522 .
Hiromi Sakai, Keitaro Sou, Shinji Takeoka, Koichi Kobayashi & Eishun Tsuchida. 2005. Artificial Oxygen Carrier. Artificial Oxygen Carrier 135 168 .
K. Kobayashi, H. Horinouchi, M. Watanabe, Y. Izumi, Y. Teramura, A. Nakagawa, Y. Huang, K. Sou, H. Sakai, T. Komatsu, S. Takeoka & E. Tsuchida. 2005. Artificial Oxygen Carrier. Artificial Oxygen Carrier 1 21 .
Eishun Tsuchida, Hiromi Sakai, Teruyuki Komatsu, Shinji Takeoka, Yubin Huang, Keitaro Sou, Akito Nakagawa, Yuji Teramura & Koichi Kobayashi. (2005) Oxygen infusions (hemoglobin-vesicles and albumin-hemes) based on nano-molecular sciences. Polymers for Advanced Technologies 16:2-3, pages 73-83.
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Akira Yoshizu, Yotaro Izumi, Sungick Park, Hiromi Sakai, Shinji Takeoka, Hirohisa Horinouchi, Eiji Ikeda, Eishun Tsuchida & Koichi Kobayashi. (2004) Hemorrhagic Shock Resuscitation With an Artificial Oxygen Carrier, Hemoglobin Vesicle, Maintains Intestinal Perfusion and Suppresses the Increase in Plasma Tumor Necrosis Factor-α. ASAIO Journal 50:5, pages 458-463.
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V.D. Awasthi, D. Garcia, R. Klipper, W.T. Phillips & B.A. Goins. (2004) Kinetics of liposome-encapsulated hemoglobin after 25% hypovolemic exchange transfusion. International Journal of Pharmaceutics 283:1-2, pages 53-62.
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Hiromi Sakai, Yohei Masada, Hirohisa Horinouchi, Manabu Yamamoto, Eiji Ikeda, Shinji Takeoka, Koichi Kobayashi & Eishun Tsuchida. (2004) Hemoglobin-vesicles suspended in recombinant human serum albumin for resuscitation from hemorrhagic shock in anesthetized rats*. Critical Care Medicine 32:2, pages 539-545.
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Kazuhiro Akama, W.-L. Gong, Lin Wang, Satoru Tokuyama & Eishun Tsuchida. (1999) Stable preservation of hemoglobin vesicles as a blood substitute. Polymers for Advanced Technologies 10:5, pages 293-298.
Crossref
Klaus F. Waschke & Thomas Frietsch. (1999) Modified haemoglobins and perfluorocarbons. Current Opinion in Anaesthesiology 12:2, pages 195-202.
Crossref
Paul A. Manner, Harry E. Rubash & James H. Herndon. (1998) Prospectus. Clinical Orthopaedics and Related Research 357, pages 101-115.
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