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Research Article

Deregulation of STAT-5 isoforms in the development of HPV-mediated cervical carcinogenesis

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Pages 178-188 | Received 11 Jan 2010, Accepted 09 Mar 2010, Published online: 23 Apr 2010

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Therese Högfeldt, Abeer A. Bahnassy, Anna Kwiecinska, Anders Österborg, Katja Pokrovskaja Tamm, Anna Porwit, Abdel-Rahman N. Zekri, Joachim Lundahl, Hussein M. Khaled, Håkan Mellstedt & Ali Moshfegh. (2013) Patients with activated B-cell like diffuse large B-cell lymphoma in high and low infectious disease areas have different inflammatory gene signatures. Leukemia & Lymphoma 54:5, pages 996-1003.
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Neha Singh, Showket Hussain, Mausumi Bharadwaj, Nandita Kakkar, S. K. Singh & Ranbir C. Sobti. (2012) Overexpression of signal transducer and activator of transcription (STAT-3 and STAT-5) transcription factors and alteration of suppressor of cytokine signaling (SOCS-1) protein in prostate cancer. Journal of Receptors and Signal Transduction 32:6, pages 321-327.
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Showket Hussain, Neha Singh, Irfana Salam, Kapil Bandil, M Yuvaraj, Mohammad Akbar Bhat, Mohammad Muzaffar Mir, Mushtaq A. Siddiqi, Ranbir C Sobti, Mausumi Bharadwaj & Bhudev C. Das. (2011) Methylation-mediated gene silencing of suppressor of cytokine signaling-1 (SOCS-1) gene in esophageal squamous cell carcinoma patients of Kashmir valley. Journal of Receptors and Signal Transduction 31:2, pages 147-156.
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Chunnian Zhang, Liqin Gu, Juan Xiao & Feng Jin. (2023) Knockdown of RBM15 inhibits tumor progression and the JAK-STAT signaling pathway in cervical cancer. BMC Cancer 23:1.
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Arturo Valle-Mendiola, Adriana Gutiérrez-Hoya & Isabel Soto-Cruz. (2023) JAK/STAT Signaling and Cervical Cancer: From the Cell Surface to the Nucleus. Genes 14:6, pages 1141.
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Kagiso Laka, Ladislaus Mdee & Zukile Mbita. (2022) Drimia calcarata Bulb Extracts Deactivate the PI3K Signalling Pathway in Cervical HPV-18 Positive HeLa Cells. Clinical Complementary Medicine and Pharmacology 2:4, pages 100054.
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Solmaz Ohadian Moghadam, Mohammad Reza Nowroozi, Ali Nowroozi & Pouria Rezaei. (2021) Infection with Human Papillomavirus as a Potential Risk Factor for Prostate Cancer: A Case-control Study. Archives of Clinical Infectious Diseases 16:1.
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Qun Wang, Aurelia Vattai, Theresa Vilsmaier, Till Kaltofen, Alexander Steger, Doris Mayr, Sven Mahner, Udo Jeschke & Helene Hildegard Heidegger. (2021) Immunogenomic Identification for Predicting the Prognosis of Cervical Cancer Patients. International Journal of Molecular Sciences 22:5, pages 2442.
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Mansour A. Alghamdi, Laith N. AL-Eitan, Amneh H. Tarkhan & Firas A. Al-Qarqaz. (2021) Global gene methylation profiling of common warts caused by human papillomaviruses infection. Saudi Journal of Biological Sciences 28:1, pages 612-622.
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Laith N. AL-Eitan, Mansour A. Alghamdi, Amneh H. Tarkhan & Firas A. Al-Qarqaz. (2020) Genome-wide identification of methylated CpG sites in nongenital cutaneous warts. BMC Medical Genomics 13:1.
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Angela R. Harrison & Gregory W. Moseley. (2020) The Dynamic Interface of Viruses with STATs. Journal of Virology 94:22.
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Adriana Gutiérrez-Hoya & Isabel Soto-Cruz. (2020) Role of the JAK/STAT Pathway in Cervical Cancer: Its Relationship with HPV E6/E7 Oncoproteins. Cells 9:10, pages 2297.
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Ethan L. Morgan & Andrew Macdonald. (2019) JAK2 Inhibition Impairs Proliferation and Sensitises Cervical Cancer Cells to Cisplatin-Induced Cell Death. Cancers 11:12, pages 1934.
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Zonghui Guo, Yin Tang, Youwei Fu & Junjie Wang. (2019) Decreased expression of STAT5A predicts poor prognosis in osteosarcoma. Pathology - Research and Practice 215:3, pages 519-524.
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James I. MullinsLisa M. Frenkel. (2017) Clonal Expansion of Human Immunodeficiency Virus–Infected Cells and Human Immunodeficiency Virus Persistence During Antiretroviral Therapy. The Journal of Infectious Diseases 215:suppl_3, pages S119-S127.
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Arturo Valle-Mendiola, Adriana Gutiérrez-Hoya, María del Carmen Lagunas-Cruz, Benny Weiss-Steider & Isabel Soto-Cruz. (2016) Pleiotropic Effects of IL-2 on Cancer: Its Role in Cervical Cancer. Mediators of Inflammation 2016, pages 1-11.
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TAO SUN, YANFEI JIA & DONGJIE XIAO. (2015) Interference of STAT 5b expression enhances the chemo-sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway-mediated cell apoptosis. Oncology Reports 34:1, pages 227-234.
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Neha Singh, Showket Hussain, Nandita Kakkar, Shrawan K. Singh, Ranbir C. Sobti & Mausumi Bharadwaj. (2015) Implication of high risk Human papillomavirus HR-HPV infection in prostate cancer in Indian population- A pioneering case-control analysis. Scientific Reports 5:1.
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Kathryn H. Richards, Rosella Doble, Christopher W. Wasson, Mohammed Haider, G. Eric Blair, Miriam Wittmann & Andrew Macdonald. (2014) Human Papillomavirus E7 Oncoprotein Increases Production of the Anti-Inflammatory Interleukin-18 Binding Protein in Keratinocytes. Journal of Virology 88:8, pages 4173-4179.
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Qian Yang, Min Li, Tao Wang, Hong Xu, Wenqiao Zang & Guoqiang Zhao. (2013) Effect of STAT5 silenced by siRNA on proliferation apoptosis and invasion of esophageal carcinoma cell line Eca-109. Diagnostic Pathology 8:1.
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Shiyuan Hong & Laimonis A. Laimins. (2013) The JAK-STAT Transcriptional Regulator, STAT-5, Activates the ATM DNA Damage Pathway to Induce HPV 31 Genome Amplification upon Epithelial Differentiation. PLoS Pathogens 9:4, pages e1003295.
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Neha Singh, R.C. Sobti, Vanita Suri, Raje Nijhawan, Shweta Sharma, B.C. Das, Mausumi Bharadwaj & Showket Hussain. (2013) Downregulation of tumor suppressor gene PML in uterine cervical carcinogenesis: Impact of human papillomavirus infection (HPV). Gynecologic Oncology 128:3, pages 420-426.
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Jeffrey W. Schmidt & Kay-Uwe Wagner. 2012. Jak-Stat Signaling : From Basics to Disease. Jak-Stat Signaling : From Basics to Disease 259 288 .
R. C. Sobti, Neha Singh, Showket Hussain, Vanita Suri, Raje Nijhawan, A. C. Bharti, Mausumi Bharadwaj & B. C. Das. (2011) Aberrant promoter methylation and loss of Suppressor of Cytokine Signalling-1 gene expression in the development of uterine cervical carcinogenesis. Cellular Oncology 34:6, pages 533-543.
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G. Ferbeyre & R. Moriggl. (2011) The role of Stat5 transcription factors as tumor suppressors or oncogenes. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1815:1, pages 104-114.
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Daoxin Jin, Wenqiao Zang, Tao Wang, Min Li, Jieru Wan & Guoqiang Zhao. (2010) The effect of STAT5 silenced by siRNA on proliferation, apoptosis and invasion of esophageal carcinoma cell line EC9706. The Chinese-German Journal of Clinical Oncology 9:12, pages 692-696.
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