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Journal of Receptors and Signal Transduction Volume 33, 2013 - Issue 2
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Research Article

P66Shc-rac1 pathway-mediated ROS production and cell migration is downregulated by ascorbic acid

Deeba KirmaniDepartment of Biotechnology
,
Hina F. BhatDepartment of Biotechnology
,
Muneesa BashirDepartment of Biotechnology
,
Mohammad A. ZargarDepartment of Biochemistry, University of Kashmir Jammu and KashmirIndia
&
Firdous A. KhandayDepartment of BiotechnologyCorrespondence[email protected]
Pages 107-113 | Received 10 Nov 2012, Accepted 23 Jan 2013, Published online: 06 Mar 2013

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Desmond D Mascarenhas, David N Herndon & Istvan Arany. (2017) Epigenetic memory of oxidative stress: does nephrilin exert its protective effects via Rac1?. Biologics: Targets and Therapy 11, pages 97-106.
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Articles from other publishers (11)

Dominik T. Koch, Haochen Yu, Iris Beirith, Malte Schirren, Moritz Drefs, Yunfei Liu, Mathilda Knoblauch, Dionysios Koliogiannis, Weiwei Sheng, Enrico N. De Toni, Alexandr V. Bazhin, Bernhard W. Renz, Markus O. Guba, Jens Werner & Matthias Ilmer. (2023) Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and RAC1 in hepatocellular carcinoma cells. Journal of Translational Medicine 21:1.
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Tânia Fernandes, M. Rosário Domingues, Cláudia F. Pereira & Paula I. Moreira. 2023. Modulation of Oxidative Stress. Modulation of Oxidative Stress 81 96 .
Hilal Ahmad Mir, Roshia Ali, Zahoor Ahmad Wani & Firdous Ahmad Khanday. (2022) Pro-oxidant vitamin C mechanistically exploits p66Shc/Rac1 GTPase pathway in inducing cytotoxicity. International Journal of Biological Macromolecules 205, pages 154-168.
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Roshia Ali, Hilal Ahmad Mir, Rabia Hamid, Basharat Bhat, Riaz A. Shah, Firdous A. Khanday & Sahar Saleem Bhat. (2022) Actin Modulation Regulates the Alpha-1-Syntrophin/p66Shc Mediated Redox Signaling Contributing to the RhoA GTPase Protein Activation in Breast Cancer Cells. Frontiers in Oncology 12.
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Hilal Ahmad Mir, Roshia Ali, Umar Mushtaq & Firdous A. Khanday. (2020) Structure-functional implications of longevity protein p66Shc in health and disease. Ageing Research Reviews 63, pages 101139.
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Manish MishraArul J. DuraisamySudarshan BhattacharjeeRenu A. Kowluru. (2019) Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy. Antioxidants & Redox Signaling 30:13, pages 1621-1634.
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Matthew A. Ingersoll, Yu-Wei Chou, Jamie S. Lin, Ta-Chun Yuan, Dannah R. Miller, Yan Xie, Yaping Tu, Rebecca E. Oberley-Deegan, Surinder K. Batra & Ming-Fong Lin. (2018) p66Shc regulates migration of castration-resistant prostate cancer cells. Cellular Signalling 46, pages 1-14.
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Fabio Di Lisa, Marco Giorgio, Peter Ferdinandy & Rainer Schulz. (2017) New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases. British Journal of Pharmacology 174:12, pages 1690-1703.
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Xiaoshan Yang, Rong Xu, Yajun Lin, Yongzhan Zhen, Jie Wei, Gang Hu & Hongfan Sun. (2016) Recombinant adenovirus of human p66Shc inhibits MCF-7 cell proliferation. Scientific Reports 6:1.
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G. Paulsen, H. Hamarsland, K. T. Cumming, R. E. Johansen, J. J. Hulmi, E. Børsheim, H. Wiig, I. Garthe & T. Raastad. (2014) Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training. The Journal of Physiology 592:24, pages 5391-5408.
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Eric Haines, Caroline Saucier & Audrey Claing. (2014) The Adaptor Proteins p66Shc and Grb2 Regulate the Activation of the GTPases ARF1 and ARF6 in Invasive Breast Cancer Cells. Journal of Biological Chemistry 289:9, pages 5687-5703.
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