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Review Article

Why receptor reserve matters for neurokinin1 (NK1) receptor antagonists

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Pages 333-337 | Received 14 Jun 2013, Accepted 28 Aug 2013, Published online: 09 Oct 2013

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Roberto Mandrioli & Laura Mercolini. (2015) Discontinued anxiolytic drugs (2009 – 2014). Expert Opinion on Investigational Drugs 24:4, pages 557-573.
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Tricia A. Meyer, Ashraf S. Habib, Deborah Wagner & Tong J. Gan. (2023) Neurokinin‐1 receptor antagonists for the prevention of postoperative nausea and vomiting. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy.
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Jesse R. Schank. (2020) Neurokinin receptors in drug and alcohol addiction. Brain Research 1734, pages 146729.
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Britta S. Nelson, Hannah D. Fulenwider, Sadie E. Nennig, Britessia M. Smith, Michelle K. Sequeira, Scott H. Chimberoff, Christopher T. Richie, Kejun Cheng, Kenner C. Rice, Brandon K. Harvey, Markus Heilig & Jesse R. Schank. (2019) Escalated Alcohol Self-Administration and Sensitivity to Yohimbine-Induced Reinstatement in Alcohol Preferring Rats: Potential Role of Neurokinin-1 Receptors in the Amygdala. Neuroscience 413, pages 77-85.
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Nadia M.J. Rupniak & Mark S. Kramer. (2017) NK1 receptor antagonists for depression: Why a validated concept was abandoned. Journal of Affective Disorders 223, pages 121-125.
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Renzo Carletti, Stefano Tacconi, Manolo Mugnaini & Philip Gerrard. (2017) Receptor distribution studies. Current Opinion in Pharmacology 35, pages 94-100.
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Jennifer A Rinker & Patrick J Mulholland. (2017) Promising pharmacogenetic targets for treating alcohol use disorder: evidence from preclinical models. Pharmacogenomics 18:6, pages 555-570.
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Jesse R. Schank & Markus Heilig. 2017. The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption. The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption 151 175 .
SHELDON H. PRESKORN. (2014) CNS Drug Development. Journal of Psychiatric Practice 20:6, pages 460-465.
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William A. Ball, Duane B. Snavely, Richard J. Hargreaves, Armin Szegedi, Christopher Lines & Scott A. Reines. (2014) Addition of an NK 1 receptor antagonist to an SSRI did not enhance the antidepressant effects of SSRI monotherapy: results from a randomized clinical trial in patients with major depressive disorder . Human Psychopharmacology: Clinical and Experimental 29:6, pages 568-577.
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Jesse R. Schank. (2014) The Neurokinin-1 Receptor in Addictive Processes. Journal of Pharmacology and Experimental Therapeutics 351:1, pages 2-8.
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David G. Trist & Alan Bye. (2014) Editorial overview: Neurosciences: Clinical pharmacology today in neuroscience drug discovery. Current Opinion in Pharmacology 14, pages v-vi.
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