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Journal of Receptors and Signal Transduction Volume 34, 2014 - Issue 6
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Research Article

The renoprotective effects of berberine via the EP4-Gαs-cAMP signaling pathway in different stages of diabetes in rats

Yang YangInstitute of Clinical Pharmacology, Key Laboratory of Anti-inflammatory and Immune Medicine, Anhui Medical University, Ministry of Education HefeiChinaCorrespondence[email protected]
,
Weijian NiInstitute of Clinical Pharmacology, Key Laboratory of Anti-inflammatory and Immune Medicine, Anhui Medical University, Ministry of Education HefeiChina
,
Ming CaiInstitute of Pharmacy, Anhui University of Chinese Medicine Hefei, AnhuiChina
,
Liqin TangAffiliated Anhui Provincial Hospital, Anhui Medical University Hefei, AnhuiChina
&
Wei WeiInstitute of Clinical Pharmacology, Key Laboratory of Anti-inflammatory and Immune Medicine, Anhui Medical University, Ministry of Education HefeiChina
Pages 445-455 | Received 20 Sep 2013, Accepted 04 Apr 2014, Published online: 22 May 2014

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Hai-Hua Ding, Wei-Jian Ni, Li-Qin Tang & Wei Wei. (2016) G protein-coupled receptors: potential therapeutic targets for diabetic nephropathy. Journal of Receptors and Signal Transduction 36:4, pages 411-421.
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Articles from other publishers (14)

Shuangyuan Hu, Jundong Wang, E. Liu, Xiaomei Zhang, Juyi Xiang, Wei Li, Pengfei Wei, Jinhao Zeng, Yi Zhang & Xiao Ma. (2022) Protective effect of berberine in diabetic nephropathy: A systematic review and meta-analysis revealing the mechanism of action. Pharmacological Research 185, pages 106481.
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Ehsan Dehdashtian, Mohammad Hossein Pourhanifeh, Karim Hemati, Saeed Mehrzadi & Azam Hosseinzadeh. (2020) Therapeutic application of nutraceuticals in diabetic nephropathy: Current evidence and future implications. Diabetes/Metabolism Research and Reviews 36:8.
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Dorin Dragoș, Maria Mirabela Manea, Delia Timofte & Dorin Ionescu. (2020) Mechanisms of Herbal Nephroprotection in diabetes mellitus. Journal of Diabetes Research 2020, pages 1-31.
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Wei‐Jian Ni, Hong Zhou, Hai‐Hua Ding & Li‐Qin Tang. (2019) Berberine ameliorates renal impairment and inhibits podocyte dysfunction by targeting the phosphatidylinositol 3‐kinase–protein kinase B pathway in diabetic rats. Journal of Diabetes Investigation 11:2, pages 297-306.
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Noriko Shinjyo, James Parkinson, Jimmy Bell, Tatsuro Katsuno & Annie Bligh. (2020) Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review. Journal of Integrative Medicine 18:2, pages 125-151.
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Qian Ran, Jin Wang, Lin Wang, Hai-rong Zeng, Xiang-bo Yang & Qin-wan Huang. (2019) Rhizoma coptidis as a Potential Treatment Agent for Type 2 Diabetes Mellitus and the Underlying Mechanisms: A Review. Frontiers in Pharmacology 10.
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Ying-Ying Wang, Li-Qin Tang & Wei Wei. (2018) Berberine attenuates podocytes injury caused by exosomes derived from high glucose-induced mesangial cells through TGFβ1-PI3K/AKT pathway. European Journal of Pharmacology 824, pages 185-192.
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Yuan-Ye Qiu, Li-Qin Tang & Wei Wei. (2017) Berberine exerts renoprotective effects by regulating the AGEs-RAGE signaling pathway in mesangial cells during diabetic nephropathy. Molecular and Cellular Endocrinology 443, pages 89-105.
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Li-Qin Tang, Wei-Jian Ni, Ming Cai, Hai-Hua Ding, Sheng Liu & Shan-Tang Zhang. (2016) Renoprotective effects of berberine and its potential effect on the expression of β -arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic nephropathy rats . Journal of Diabetes 8:5, pages 693-700.
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Jing Yu, Wei Gong, Yimei Wu, Shuzhen Li, Yiyun Cui, Yifei Ma, Yue Zhang, Guangrui Yang, Songming Huang, Zhanjun Jia & Aihua Zhang. (2016) mPGES-1-derived PGE 2 contributes to adriamycin-induced podocyte injury . American Journal of Physiology-Renal Physiology 310:6, pages F492-F498.
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Masaaki Kawano, Rie Takagi, Atsushi Kaneko & Sho Matsushita. (2015) Berberine is a dopamine D1- and D2-like receptor antagonist and ameliorates experimentally induced colitis by suppressing innate and adaptive immune responses. Journal of Neuroimmunology 289, pages 43-55.
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Wei-Jian Ni, Hai-Hua Ding, Hong Zhou, Yuan-Ye Qiu & Li-Qin Tang. (2015) Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats. European Journal of Pharmacology 764, pages 448-456.
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Wei-Jian Ni, Hai-Hua Ding & Li-Qin Tang. (2015) Berberine as a promising anti-diabetic nephropathy drug: An analysis of its effects and mechanisms. European Journal of Pharmacology 760, pages 103-112.
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Zhanjun Jia, Yue Zhang, Guixia Ding, Kristina Marie Heiney, Songming Huang & Aihua Zhang. (2015) Role of COX-2/mPGES-1/Prostaglandin E2 Cascade in Kidney Injury. Mediators of Inflammation 2015, pages 1-8.
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