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Journal of Receptors and Signal Transduction Volume 35, 2015 - Issue 5
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Research Article

Identification of metals from osteoblastic ST-2 cell supernatants as novel OGR1 agonists

Rie Abe-OhyaCardiovascular-Metabolics Research Laboratories, Research Oversight Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan, Correspondence[email protected]
,
Tomio IshikawaDiscovery Science and Technology Department, Drug Discovery and Biomedical Technology Unit, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan, and
,
Hideyuki ShiozawaDrug Metabolism & Pharmacokinetics Research Laboratories, and
,
Koji SudaFrontier Research Laboratories, Research Oversight Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan
&
Futoshi NaraCardiovascular-Metabolics Research Laboratories, Research Oversight Function, R&D Division, Daiichi Sankyo Co., Ltd., Tokyo, Japan,
Pages 485-492 | Received 08 Nov 2014, Accepted 01 Feb 2015, Published online: 08 Jun 2015

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Maiko Kadowaki, Koichi Sato, Hisashi Kamio, Makoto Kumagai, Rikishi Sato, Takafumi Nyui, Yukihiro Umeda, Yuko Waseda, Masaki Anzai, Haruka Aoki-Saito, Yasuhiko Koga, Takeshi Hisada, Hideaki Tomura, Fumikazu Okajima & Tamotsu Ishizuka. (2021) Metal-Stimulated Interleukin-6 Production Through a Proton-Sensing Receptor, Ovarian Cancer G Protein-Coupled Receptor 1, in Human Bronchial Smooth Muscle Cells: A Response Inhibited by Dexamethasone. Journal of Inflammation Research 14, pages 7021-7034.
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Jun Negishi, Yuka Omori, Mami Shindo, Hayate Takanashi, Shiori Musha, Suminori Nagayama, Jun Hirayama, Hiroshi Nishina, Takashi Nakakura, Chihiro Mogi, Koichi Sato, Fumikazu Okajima, Yuta Mochimaru & Hideaki Tomura. (2017) Manganese and cobalt activate zebrafish ovarian cancer G-protein-coupled receptor 1 but not GPR4. Journal of Receptors and Signal Transduction 37:4, pages 401-408.
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Articles from other publishers (7)

Masahito Deai, Rin Oya, Naosi Saso, Asahi Tanaka, Izumi Uchida, Yuta Miyake, Ryo Tachihara, Miku Otsugu, Ayumi Mine, Koichi Sato & Hideaki Tomura. (2022) Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells. Biochemical and Biophysical Research Communications 626, pages 15-20.
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Xi-Ping Huang, Terrence P. Kenakin, Shuo Gu, Brian K. Shoichet & Bryan L. Roth. (2020) Differential Roles of Extracellular Histidine Residues of GPR68 for Proton-Sensing and Allosteric Modulation by Divalent Metal Ions. Biochemistry 59:38, pages 3594-3614.
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Koichi Sato, Chihiro Mogi, Alan J. Mighell & Fumikazu Okajima. (2020) A missense mutation of Leu74Pro of OGR1 found in familial amelogenesis imperfecta actually causes the loss of the pH-sensing mechanism. Biochemical and Biophysical Research Communications 526:4, pages 920-926.
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Syo Murakami, Yuta Mochimaru, Shiori Musha, Ryotaro Kojima, Masahito Deai, Chihiro Mogi, Koichi Sato, Fumikazu Okajima & Hideaki Tomura. (2020) Species-Dependent Enhancement of Ovarian Cancer G Protein-Coupled Receptor 1 Activation by Ogerin. Zoological Science 37:2, pages 103.
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Xufen Yu, Xi-Ping Huang, Terry P. Kenakin, Samuel T. Slocum, Xin Chen, Michael L. Martini, Jing Liu & Jian Jin. (2019) Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68). Journal of Medicinal Chemistry 62:16, pages 7557-7574.
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Yuta Mochimaru, Jun Negishi, Syo Murakami, Shiori Musha, Koichi Sato, Fumikazu Okajima & Hideaki Tomura. (2018) Metals Differentially Activate Ovarian Cancer G Protein-Coupled Receptor 1 in Various Species. Zoological Science 35:2, pages 109-114.
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Izumi Kaji & Jonathan D. Kaunitz. 2018. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 671 682 .

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