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Research Article

Evodiamine inhibits the proliferation of leukemia cell line K562 by regulating peroxisome proliferators-activated receptor gamma (PPARγ) pathway

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Pages 422-428 | Received 19 Aug 2015, Accepted 01 Nov 2015, Published online: 16 Dec 2015

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Qing Fang, Siyi Jiang & Chengyuan Li. (2019) Evodiamine Selectively Inhibits Multiple Myeloma Cell Growth by Triggering Activation of Intrinsic Apoptosis Pathway. OncoTargets and Therapy 12, pages 11383-11391.
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Articles from other publishers (15)

Qiang Yu, Fan Wang, Saeid Baroutian, Yu Zhang, Zhongming Wang, Zhenhong Yuan & Xiaoyan Chen. (2023) A deep eutectic solvent binary-phase system for alkaloid extraction from Chinese herb Evodia lepta residue and its mechanism. Journal of Cleaner Production 398, pages 136645.
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Che-Yuan Hu, Hung-Tsung Wu, Yan-Shen Shan, Chung-Teng Wang, Gia-Shing Shieh, Chao-Liang Wu & Horng-Yih Ou. (2023) Evodiamine Exhibits Anti-Bladder Cancer Activity by Suppression of Glutathione Peroxidase 4 and Induction of Ferroptosis. International Journal of Molecular Sciences 24:7, pages 6021.
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Zhen Wang, Yongxia Xiong, Ying Peng, Xi Zhang, Shuang Li, Yan Peng, Xue Peng, Linsheng Zhuo & Weifan Jiang. (2023) Natural product evodiamine-inspired medicinal chemistry: Anticancer activity, structural optimization and structure-activity relationship. European Journal of Medicinal Chemistry 247, pages 115031.
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Munmun Panda, Surya Kant Tripathi, Gokhan Zengin & Bijesh K. Biswal. (2022) Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers. Cell Biology and Toxicology 39:1, pages 1-31.
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Hanbing Li, Gaohang Fu & Weihui Zhong. (2023) Natural quinazolinones: From a treasure house to promising anticancer leads. European Journal of Medicinal Chemistry 245, pages 114915.
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Meixia Fan & Lei Yao. (2022) The Synthesis, Structural Modification and Mode of Anticancer Action of Evodiamine: A Review. Recent Patents on Anti-Cancer Drug Discovery 17:3, pages 284-296.
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Chun-Han Su, Yu-Chieh Cheng, Yu-Chia Chang, Ting-Hsuan Kung, Yu-Li Chen, Kuei-Hung Lai, Hsi-Lung Hsieh, Chun-Yu Chen, Tsong-Long Hwang & Yu-Liang Yang. (2022) Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit. Molecules 27:14, pages 4462.
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Luning Li, Cunxin Zhang, Chen Huang, Xinchen Tian, Wenxue Sun & Shulong Jiang. (2022) Research Advances in Antitumor Mechanism of Evodiamine. Journal of Chemistry 2022, pages 1-12.
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Chaodan Luo, Jingwen Ai, Erfang Ren, Jianqiang Li, Chunmei Feng, Xinrong Li & Xiaojie Luo. (2021) Research progress on evodiamine, a bioactive alkaloid of Evodiae fructus : Focus on its anti‑cancer activity and bioavailability (Review) . Experimental and Therapeutic Medicine 22:5.
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Qiang Sun, Long Xie, Jiawen Song & Xiaofang Li. (2020) Evodiamine: A review of its pharmacology, toxicity, pharmacokinetics and preparation researches. Journal of Ethnopharmacology 262, pages 113164.
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Xu Hu, Dahong Li, Chun Chu, Xu Li, Xianhua Wang, Ying Jia, Huiming Hua & Fanxing Xu. (2018) Antiproliferative Effects of Alkaloid Evodiamine and Its Derivatives. International Journal of Molecular Sciences 19:11, pages 3403.
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Saghar Yousefnia, Sara Momenzadeh, Farzad Seyed Forootan, Kamran Ghaedi & Mohammad Hossein Nasr Esfahani. (2018) The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity. Gene 649, pages 14-22.
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Somi Ryu, Dae Seong Kim, Myoung Woo Lee, Ji Won Lee, Ki Woong Sung, Hong Hoe Koo & Keon Hee Yoo. (2018) Anti-leukemic effects of PPARγ ligands. Cancer Letters 418, pages 10-19.
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Kitti Pumiputavon, Tanawat Chaowasku, Chalermpong Saenjum, Maslin Osathanunkul, Boonsong Wungsintaweekul, Kriangkrai Chawansuntati, Jiraprapa Wipasa & Pathrapol Lithanatudom. (2017) Cell cycle arrest and apoptosis induction by methanolic leaves extracts of four Annonaceae plants. BMC Complementary and Alternative Medicine 17:1.
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Qunyou Tan & Jingqing Zhang. 2016. Drug Discovery from Mother Nature. Drug Discovery from Mother Nature 315 328 .

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