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Journal of Receptor Research Volume 4, 1984 - Issue 7
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Research Article

The Dissociation Rate of Unlabelled Dopamine Antagonists and Agonists from the Dopamine-D2 Receptor, Application of an Original Filter Method

JosÉE E. Leysen Department of Biochemical Pharmacology, Janssen Pharmaceutica, Turnhoutseweg 30, B-2340, Beerse, Belgium
&
Walter Gommeren Department of Biochemical Pharmacology, Janssen Pharmaceutica, Turnhoutseweg 30, B-2340, Beerse, Belgium
Pages 817-845 | Published online: 26 Sep 2008

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Georges Vauquelin & Isabelle Van Liefde. (2012) Radioligand dissociation measurements: potential interference of rebinding and allosteric mechanisms and physiological relevance of the biological model systems. Expert Opinion on Drug Discovery 7:7, pages 583-595.
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J. E. Hawkinson, M. P. Goeldner, C. J. Palmer & J. E. Casida. (1991) Photoaffinity Ligands for the [3H]tbob Binding Site of the GabaA Receptor. Journal of Receptor Research 11:1-4, pages 391-405.
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Josée E. Leysen, Walter Gommeren & Paul van Gompel. (1988) The Dissociation Rate of Unlabelled Drugs from Receptor Sites: A Poorly Investigated, Yet Important Aspect in Receptor Research. Studies on the Serotonin-S2 Receptor. Journal of Receptor Research 8:1-4, pages 547-559.
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J. E. Leysen, W. Gommeren, P. F. M. Janssen, P. Gompel & P. A. J. Janssen. 1988. Psychopharmacology: Current Trends. Psychopharmacology: Current Trends 12 26 .
A.M. Garrigues, F. Gehelmann, J.M. Girault, M. Delaage & J. Labouesse. (1987) Haloperidol-succinylglycyl[ 125 I]iodotyrosine, a novel iodinated ligand for dopamine D 2 receptors . FEBS Letters 224:2, pages 267-271.
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Jos�e E. Leysen & Walter Gommeren. (1986) Drug-receptor dissociation time, new tool for drug research: Receptor binding affinity and drug-receptor dissociation profiles of serotonin-S2, Dopamine-D2, histamine-H1 antagonists, and opiates. Drug Development Research 8:1-4, pages 119-131.
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W Wouters, J Van Dun, J E Leysen & P M Laduron. (1985) Photoaffinity probes for serotonin and histamine receptors. Synthesis and characterization of two azide analogues of ketanserin.. Journal of Biological Chemistry 260:14, pages 8423-8429.
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Walter Wouters, Jacky Van Dun, Josee E. Leysen & Pierre M. Laduron. (1985) Photoaffinity labelling of serotonin-S2 receptors with 7-azidoketanserin. European Journal of Pharmacology 107:3, pages 399-400.
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