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Journal of Receptors and Signal Transduction Volume 17, 1997 - Issue 1-3
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Original Article

Investigation of Growth Hormone Releasing Hormone Receptor Structure and Activity Using Yeast Expression Technologies

Eileen M. Kajkowski American Cyanamid Company, P.O. Box 400 Princeton, New Jersey, 08543, USA [email protected]
,
Laura A. Price American Cyanamid Company, P.O. Box 400 Princeton, New Jersey, 08543, USA [email protected]
,
Mark H. Pausch American Cyanamid Company, P.O. Box 400 Princeton, New Jersey, 08543, USA [email protected]
,
Kathleen H. Young American Cyanamid Company, P.O. Box 400 Princeton, New Jersey, 08543, USA [email protected]
&
Bradley A. Ozenberger American Cyanamid Company, P.O. Box 400 Princeton, New Jersey, 08543, USA [email protected]
Pages 293-303 | Published online: 26 Jun 2009

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Edith Pajot‐Augy, Mark Crowe, Grégoire Levasseur, Roland Salesse & Ian Connerton. (2003) Engineered Yeasts as Reporter Systems for Odorant Detection. Journal of Receptors and Signal Transduction 23:2-3, pages 155-171.
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Bruce D. Gaylinn. (2002) Growth Hormone Releasing Hormone Receptor. Receptors and Channels 8:3-4, pages 155-162.
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Mark L. Crowe, Barry N. Perry & Ian F. Connerton. (2000) GOlf Complements A Gpa1 Null Mutation in Olf Saccharomyces Cerevisiae and Functionally Couples to the Ste2 Pheromone Receptor. Journal of Receptors and Signal Transduction 20:1, pages 61-73.
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Kathleen H Young. (1999) A yeast two-hybrid, systems based approach for the identification of novel pharmaceutical entities. Expert Opinion on Therapeutic Patents 9:7, pages 897-915.
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Xuesong Wang, Gerard J.P. van Westen, Laura H. Heitman & Adriaan P. IJzerman. (2021) G protein-coupled receptors expressed and studied in yeast. The adenosine receptor as a prime example. Biochemical Pharmacology 187, pages 114370.
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William M. Shaw, Hitoshi Yamauchi, Jack Mead, Glen-Oliver F. Gowers, David J. Bell, David Öling, Niklas Larsson, Mark Wigglesworth, Graham Ladds & Tom Ellis. (2019) Engineering a Model Cell for Rational Tuning of GPCR Signaling. Cell 177:3, pages 782-796.e27.
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Zachary Britton, Carissa Young, Özge Can, Patrick McNeely, Andrea Naranjo & Anne Skaja Robinson. 2011. Production of Membrane Proteins. Production of Membrane Proteins 37 73 .
Shayne Cox GadArianna Loregian & Giorgio Palù. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Chaoyang Xue, Yen-Ping Hsueh & Joseph Heitman. (2008) Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi. FEMS Microbiology Reviews 32:6, pages 1010-1032.
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Graham Ladds, Alan Goddard, Claire Hill, Steven Thornton & John Davey. (2007) Differential effects of RGS proteins on Gαq and Gα11 activity. Cellular Signalling 19:1, pages 103-113.
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M. Roginskaya, S. M. Connelly, K. S. Kim, D. Patel & M. E. Dumont. (2004) Effects of mutations in the N terminal region of the yeast G protein α-subunit Gpa1p on signaling by pheromone receptors. Molecular Genetics and Genomics 271:2, pages 237-248.
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Desiree H. Floyd, Adi Geva, Stephen P. Bruinsma, Mark C. Overton, Kendall J. Blumer & Thomas J. Baranski. (2003) C5a Receptor Oligomerization. Journal of Biological Chemistry 278:37, pages 35354-35361.
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Kelly E. Mayo, Laurence J. Miller, Dominique Bataille, Stéphane Dalle, Burkhard Göke, Bernard Thorens & Daniel J. Drucker. (2003) International Union of Pharmacology. XXXV. The Glucagon Receptor Family. Pharmacological Reviews 55:1, pages 167-194.
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Andjelka Ćelić, Negin P. Martin, Cagdas D. Son, Jeffrey M. Becker, Fred Naider & Mark E. Dumont. (2003) Sequences in the Intracellular Loops of the Yeast Pheromone Receptor Ste2p Required for G Protein Activation. Biochemistry 42:10, pages 3004-3017.
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Negin P Martin, Andjelka Ćelić & Mark E Dumont. (2002) Mutagenic mapping of helical structures in the transmembrane segments of the yeast α-factor receptor 1 1Edited by I. B. Holland. Journal of Molecular Biology 317:5, pages 765-788.
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Kathleen G. Valentine, Shi-Feng Liu, Francesca M. Marassi, Gianluigi Veglia, Stanley J. Opella, Fa-Xiang Ding, Shu-Hua Wang, Boris Arshava, Jeffrey M. Becker & Fred Naider. (2001) Structure and topology of a peptide segment of the 6th transmembrane domain of theSaccharomyces cerevisae ?-factor receptor in phospholipid bilayers. Biopolymers 59:4, pages 243-256.
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Pascal Leplatois, Annick Josse, Marie Guillemot, Martine Febvre, Natalio Vita, Pascual Ferrara & Gérard Loison. (2001) Neurotensin induces mating in Saccharomyces cerevisiae cells that express human neurotensin receptor type 1 in place of the endogenous pheromone receptor . European Journal of Biochemistry 268:18, pages 4860-4867.
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Isolde Erlenbach, Evi Kostenis, Clarice Schmidt, Claudine Serradeil-Le Gal, Danielle Raufaste, Mark E. Dumont, Mark H. Pausch & Jürgen Wess. (2001) Single Amino Acid Substitutions and Deletions That Alter the G Protein Coupling Properties of the V2 Vasopressin Receptor Identified in Yeast by Receptor Random Mutagenesis. Journal of Biological Chemistry 276:31, pages 29382-29392.
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Donald Kirsch, William Baumbach, Julia Heinrich, Margaret Lai, Mark Pausch, Laura Sarokin, Sanford Silverman & James Walsh. 2001. Handbook of Drug Screening. Handbook of Drug Screening.
Prabhavathi Fernandes. 2001. Handbook of Drug Screening. Handbook of Drug Screening.
Isolde Erlenbach, Evi Kostenis, Clarice Schmidt, Fadi F. Hamdan, Mark H. Pausch & Jürgen Wess. (2001) Functional expression of M1, M3 and M5 muscarinic acetylcholine receptors in yeast. Journal of Neurochemistry 77:5, pages 1327-1337.
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Venita I DeAlmeida & Kelly E Mayo. 2001. 233 276 .
Doreen Ma. 2001. Progress in Drug Research 57. Progress in Drug Research 57 117 162 .
Christine M. Sommers, Negin P. Martin, Ayca Akal-Strader, Jeffrey M. Becker, Fred Naider & Mark E. Dumont. (2000) A Limited Spectrum of Mutations Causes Constitutive Activation of the Yeast α-Factor Receptor. Biochemistry 39:23, pages 6898-6909.
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Andrew J. Brown, Susan L. Dyos, Malcolm S. Whiteway, Julia H. M. White, Marie-Ange E. A. Watson, Martina Marzioch, Jeff J. Clare, Diane J. Cousens, Chris Paddon, Chris Plumpton, Mike A. Romanos & Simon J. Dowell. (2000) Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein ?-subunit chimeras. Yeast 16:1, pages 11-22.
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Bruce D. Gaylinn, Venita I. DeAlmeida, Charles E. LyonsJr.Jr., Kenneth C. Wu, Kelly E. Mayo & Michael O. Thorner. (1999) The Mutant Growth Hormone-Releasing Hormone (GHRH) Receptor of the Little Mouse Does Not Bind GHRH1. Endocrinology 140:11, pages 5066-5074.
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Wim Van Criekinge & Rudi Beyaert. (1999) Yeast two-hybrid: State of the art. Biological Procedures Online 2:1, pages 1-38.
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B.D. Gaylinn. (1999) Molecular and cell biology ofthe growth hormone-releasing hormone receptor. Growth Hormone & IGF Research 9, pages 37-44.
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Graeme Milligan & Stephen Rees. (1999) Chimaeric Gα proteins: their potential use in drug discovery. Trends in Pharmacological Sciences 20:3, pages 118-124.
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Gerhard Baumann & Hiralal G. Maheshwari. 1999. Hormone Resistance Syndromes. Hormone Resistance Syndromes 1 16 .
Helmut Reiländer & H Markus Weiβ. (1998) Production of G-protein-coupled receptors in yeast. Current Opinion in Biotechnology 9:5, pages 510-517.
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Tarja Kokkola, Marie-Ange Watson, Julia White, Simon Dowell, Steven M. Foord & Jarmo T. Laitinen. (1998) Mutagenesis of Human Mel1aMelatonin Receptor Expressed in Yeast Reveals Domains Important for Receptor Function. Biochemical and Biophysical Research Communications 249:2, pages 531-536.
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Lorna A. Casselton & Natalie S. Olesnicky. (1998) Molecular Genetics of Mating Recognition in Basidiomycete Fungi. Microbiology and Molecular Biology Reviews 62:1, pages 55-70.
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Lilyann Novak Frazer. (1998) One stop mycology. Mycological Research 102:1, pages 103-128.
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Prabhavathi B Fernandes. (1998) Technological advances in high-throughput screening. Current Opinion in Chemical Biology 2:5, pages 597-603.
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Mark H. Pausch. (1997) G-protein-coupled receptors in Saccharomyces cerevisiae: high-throughput screening assays for drug discovery. Trends in Biotechnology 15:12, pages 487-494.
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Channa K Jayawickreme & Thomas A Kost. (1997) Gene expression systems in the development of high-throughput screens. Current Opinion in Biotechnology 8:5, pages 629-634.
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Rainer K Brachmann & Jef D Boeke. (1997) Tag games in yeast: the two-hybrid system and beyond. Current Opinion in Biotechnology 8:5, pages 561-568.
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