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Research Article

Film coated tablets (ColoPulse technology) for targeted delivery in the lower intestinal tract: Influence of the core composition on release characteristics

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Pages 40-47 | Received 25 Jan 2010, Accepted 20 Jul 2010, Published online: 05 Oct 2010

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Marina J.M. Maurer, Reinout C.A. Schellekens, Klaus D. Wutzke & Frans Stellaard. (2013) Isotope-labelled urea to test colon drug delivery devices in vivo: principles, calculations and interpretations. Isotopes in Environmental and Health Studies 49:4, pages 473-491.
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Federica Casati, Alice Melocchi, Saliha Moutaharrik, Marco Uboldi, Anastasia Foppoli, Alessandra Maroni, Lucia Zema, Christel Neut, Florence Siepmann, Juergen Siepmann & Andrea Gazzaniga. (2020) Injection Molded Capsules for Colon Delivery Combining Time-Controlled and Enzyme-Triggered Approaches. International Journal of Molecular Sciences 21:6, pages 1917.
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Marilena Vlachou, Angeliki Siamidi & Yannis Dotsikas. (2020) Desirability Based Optimization of New Mesalazine Modified Release Formulations: Compression Coated Tablets and Mini Tablets in Capsules. Letters in Drug Design & Discovery 17:2, pages 114-123.
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Sonia Trombino, Simona Serini, Roberta Cassano & Gabriella Calviello. (2019) Xanthan gum-based materials for omega-3 PUFA delivery: Preparation, characterization and antineoplastic activity evaluation. Carbohydrate Polymers 208, pages 431-440.
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Panna Vass, Balázs Démuth, Edit Hirsch, Brigitta Nagy, Sune K. Andersen, Tamás Vigh, Geert Verreck, István Csontos, Zsombor K. Nagy & György Marosi. (2019) Drying technology strategies for colon-targeted oral delivery of biopharmaceuticals. Journal of Controlled Release 296, pages 162-178.
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Bahez Gareb, Anko C. Eissens, Jos G.W. Kosterink & Hendrik W. Frijlink. (2016) Development of a zero-order sustained-release tablet containing mesalazine and budesonide intended to treat the distal gastrointestinal tract in inflammatory bowel disease. European Journal of Pharmaceutics and Biopharmaceutics 103, pages 32-42.
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Jacoba M. Maurer, Reinout C. A. Schellekens, Hèlen M. van Rieke, Christoph Wanke, Ventzeslav Iordanov, Frans Stellaard, Klaus D. Wutzke, Gerard Dijkstra, Margot van der Zee, Herman J. Woerdenbag, Henderik W. Frijlink & Jos G. W. Kosterink. (2015) Gastrointestinal pH and Transit Time Profiling in Healthy Volunteers Using the IntelliCap System Confirms Ileo-Colonic Release of ColoPulse Tablets. PLOS ONE 10:7, pages e0129076.
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J.M. Maurer, R.C.A. Schellekens, H.M. van Rieke, F. Stellaard, K.D. Wutzke, D.J. Buurman, G. Dijkstra, H.J. Woerdenbag, H.W. Frijlink & J.G.W. Kosterink. (2013) ColoPulse tablets perform comparably in healthy volunteers and Crohn's patients and show no influence of food and time of food intake on bioavailability. Journal of Controlled Release 172:3, pages 618-624.
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Alessandra Maroni, Maria Dorly Del Curto, Lucia Zema, Anastasia Foppoli & Andrea Gazzaniga. (2013) Film coatings for oral colon delivery. International Journal of Pharmaceutics 457:2, pages 372-394.
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Alireza Abbaspourrad, Sujit S. Datta & David A. Weitz. (2013) Controlling Release From pH-Responsive Microcapsules. Langmuir 29:41, pages 12697-12702.
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