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Pharmaceutical Development and Technology Volume 16, 2011 - Issue 1
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Research Articles

Design and characterization of a laminar flow-through dissolution apparatus: Comparison of hydrodynamic conditions to those of common dissolution techniques

Kristyn GrecoDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut, USA
,
Theodore L. BergmanDepartment of Mechanical Engineering, School of Engineering, University of Connecticut, Storrs, Connecticut, USA
&
Robin BognerDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut, USACorrespondence[email protected]
Pages 75-87 | Received 17 Aug 2009, Accepted 17 Nov 2009, Published online: 27 Jan 2010

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Sarah Gordon, Kaisa Naelapää, Jukka Rantanen, Arzu Selen, Anette Müllertz & Jesper Østergaard. (2013) Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging. Pharmaceutical Development and Technology 18:6, pages 1407-1416.
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Articles from other publishers (19)

Sara B. E. Andersson, Göran Frenning & Göran Alderborn. (2021) Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities. Pharmaceutics 13:6, pages 835.
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Dominik Sleziona, Amelie Mattusch, Gerhard Schaldach, David R. Ely, Gabriele Sadowski & Markus Thommes. (2021) Determination of Inherent Dissolution Performance of Drug Substances. Pharmaceutics 13:2, pages 146.
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Ji Yeon Kim, Myung Hee Chun & Du Hyung Choi. (2021) Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design. Pharmaceutics 13:1, pages 80.
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Pooja Sane, Robin H. Bogner, Bakul Bhatnagar & Serguei Tchessalov. (2020) Reconstitution of Highly Concentrated Lyophilized Proteins: Part 1 Amorphous Formulations. Journal of Pharmaceutical Sciences 109:5, pages 1681-1691.
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Christel A.S. Bergström, Karl Box, René Holm, Wayne Matthews, Mark McAllister, Anette Müllertz, Thomas Rades, Kerstin J. Schäfer & Alexandra Teleki. (2019) Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects. European Journal of Pharmaceutics and Biopharmaceutics 139, pages 101-114.
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Mary S. Kleppe, Roy J. Haskell & Robin H. Bogner. (2018) Biorelevant Media Slows the Solution-Mediated Phase Transformation of Amorphous Spironolactone. Journal of Pharmaceutical Sciences 107:1, pages 426-435.
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Jesper Østergaard. (2018) UV imaging in pharmaceutical analysis. Journal of Pharmaceutical and Biomedical Analysis 147, pages 140-148.
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Yan He, Chris Ho, Donglai Yang, Jeane Chen & Edward Orton. (2017) Measurement and Accurate Interpretation of the Solubility of Pharmaceutical Salts. Journal of Pharmaceutical Sciences 106:5, pages 1190-1196.
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Patrick S. Wray, Wayne E. Sinclair, John W. Jones, Graham S. Clarke & Douglas Both. (2015) The use of in situ near infrared imaging and Raman mapping to study the disproportionation of a drug HCl salt during dissolution. International Journal of Pharmaceutics 493:1-2, pages 198-207.
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Amrit Paudel, Dhara Raijada & Jukka Rantanen. (2015) Raman spectroscopy in pharmaceutical product design. Advanced Drug Delivery Reviews 89, pages 3-20.
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José Raúl Medina, Dulce Karina Salazar, Marcela Hurtado, Alma Rosa Cortés & Adriana Miriam Domínguez-Ramírez. (2014) Comparative in vitro dissolution study of carbamazepine immediate-release products using the USP paddles method and the flow-through cell system. Saudi Pharmaceutical Journal 22:2, pages 141-147.
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Jesper Østergaard, Jian X. Wu, Kaisa Naelapää, Johan P. Boetker, Henrik Jensen & Jukka Rantanen. (2014) Simultaneous UV Imaging and Raman Spectroscopy for the Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing. Journal of Pharmaceutical Sciences 103:4, pages 1149-1156.
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Johan P. Boetker, Jukka Rantanen, Thomas Rades, Anette Müllertz, Jesper Østergaard & Henrik Jensen. (2013) A New Approach to Dissolution Testing by UV Imaging and Finite Element Simulations. Pharmaceutical Research 30:5, pages 1328-1337.
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Kristyn Greco & Robin Bogner. (2012) Solution-Mediated Phase Transformation: Significance During Dissolution and Implications for Bioavailability. Journal of Pharmaceutical Sciences 101:9, pages 2996-3018.
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Kristyn Greco & Robin Bogner. (2011) Solution-Mediated Phase Transformation of Haloperidol Mesylate in the Presence of Sodium Lauryl Sulfate. AAPS PharmSciTech 12:3, pages 909-916.
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Johan P. Boetker, Marja Savolainen, Vishal Koradia, Fang Tian, Thomas Rades, Anette Müllertz, Claus Cornett, Jukka Rantanen & Jesper Østergaard. (2011) Insights into the Early Dissolution Events of Amlodipine Using UV Imaging and Raman Spectroscopy. Molecular Pharmaceutics 8:4, pages 1372-1380.
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Kristyn Greco, Daniel P. Mcnamara & Robin Bogner. (2011) Solution-Mediated Phase Transformation of Salts During Dissolution: Investigation Using Haloperidol as a Model Drug. Journal of Pharmaceutical Sciences 100:7, pages 2755-2768.
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Fang Tian & Jukka Rantanen. (2011) Perspective on Water of Crystallization Affecting the Functionality of Pharmaceuticals. Food Biophysics 6:2, pages 250-258.
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Kristyn Greco & Robin Bogner. (2010) Crystallization of Amorphous Indomethacin during Dissolution: Effect of Processing and Annealing. Molecular Pharmaceutics 7:5, pages 1406-1418.
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