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Research Article

Biodegradable poly(D, L-lactide-co-glycolide) (PLGA) microspheres for sustained release of risperidone: Zero-order release formulation

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Pages 377-384 | Received 25 Oct 2009, Accepted 27 Feb 2010, Published online: 07 Apr 2010

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Atefeh Ebrahimi, Komail Sadrjavadi, Marziyeh Hajialyani, Yalda Shokoohinia & Ali Fattahi. (2018) Preparation and characterization of silk fibroin hydrogel as injectable implants for sustained release of Risperidone. Drug Development and Industrial Pharmacy 44:2, pages 199-205.
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Elham Jafarifar, Marziyeh Hajialyani, Mona Akbari, Masoud Rahimi, Yalda Shokoohinia & Ali Fattahi. (2017) Preparation of a reproducible long-acting formulation of risperidone-loaded PLGA microspheres using microfluidic method. Pharmaceutical Development and Technology 22:6, pages 836-843.
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Taieb Aouak, Mohamed Ouladsmane, Abdulaziz Ali Alghamdi, Ahmad Abdulaziz Al-Owais, Turki Mohammad Al-Turki, Zeid Abdullah Alothman & Waseem Sharaf Saeed. (2016) Fabrication of tissue engineering scaffold from poly(vinylalcohol-co-ethylene)/poly(D,L-lactic-co-glycolic acid) blend: Miscibility, thermomechanical properties, and morphology. International Journal of Polymeric Materials and Polymeric Biomaterials 65:10, pages 526-536.
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Viktor Korzhikov, Ilia Averianov, Evgeniia Litvinchuk & Tatiana B. Tennikova. (2016) Polyester-based microparticles of different hydrophobicity: the patterns of lipophilic drug entrapment and release. Journal of Microencapsulation 33:3, pages 199-208.
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Andrew Otte, Bong Kwan Soh & Kinam Park. (2023) The Impact of Post-Processing Temperature on PLGA Microparticle Properties. Pharmaceutical Research.
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Fatemeh Mohammadpour, Hossein Kamali, Farzin Hadizadeh, Maryam Bagheri, Seyedeh Nesa Rezaeian Shiadeh, Ali Nazari, Fatemeh Oroojalian & Elham Khodaverdi. (2021) The PLGA Microspheres Synthesized by a Thermosensitive Hydrogel Emulsifier for Sustained Release of Risperidone. Journal of Pharmaceutical Innovation 17:3, pages 712-724.
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Thomas L. Moore, Alexander B. Cook, Elena Bellotti, Roberto Palomba, Purnima Manghnani, Raffaele Spanò, Sayanti Brahmachari, Martina Di Francesco, Anna Lisa Palange, Daniele Di Mascolo & Paolo Decuzzi. (2022) Shape-specific microfabricated particles for biomedical applications: a review. Drug Delivery and Translational Research 12:8, pages 2019-2037.
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Christian Isalomboto Nkanga & Nicole F. Steinmetz. (2022) Injectable Hydrogel Containing Cowpea Mosaic Virus Nanoparticles Prevents Colon Cancer Growth. ACS Biomaterials Science & Engineering 8:6, pages 2518-2525.
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Liping Du, Shankui Liu, Guizhou Hao, Li Zhang, Miaomiao Zhou, Yueqing Bao, Bing Ding, Qinyong Sun & Guimin Zhang. (2021) Preparation and Release Profiles in Vitro/Vivo of Galantamine Pamoate Loaded Poly (Lactideco-Glycolide) (PLGA) Microspheres. Frontiers in Pharmacology 11.
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Liang Jin, Yijun Pan, Anna C. Pham, Ben J. Boyd, Raymond S. Norton & Joseph A. Nicolazzo. (2021) Prolonged Plasma Exposure of the Kv1.3-Inhibitory Peptide HsTX1[R14A] by Subcutaneous Administration of a Poly(Lactic-co-Glycolic Acid) (PLGA) Microsphere Formulation. Journal of Pharmaceutical Sciences 110:3, pages 1182-1188.
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Tarek M. Ibrahim, Rana G. Eissa, Nagia A. El-Megrab & Hanan M. El-Nahas. (2021) Morphological characterization of optimized risperidone-loaded in-situ gel forming implants with pharmacokinetic and behavioral assessments in rats. Journal of Drug Delivery Science and Technology 61, pages 102195.
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Christian Isalomboto Nkanga, Andreas Fisch, Mazda Rad-Malekshahi, Marieta Duvnjak Romic, Birgit Kittel, Thomas Ullrich, Jing Wang, Rui Werner Maçedo Krause, Sabine Adler, Twan Lammers, Wim E. Hennink & Farshad Ramazani. (2020) Clinically established biodegradable long acting injectables: An industry perspective. Advanced Drug Delivery Reviews 167, pages 19-46.
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Mei-Li Laracuente, Marina H. Yu & Kevin J. McHugh. (2020) Zero-order drug delivery: State of the art and future prospects. Journal of Controlled Release 327, pages 834-856.
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Christopher Isely, Alexandra C. Stevens, Gregory L. Tate, John R. Monnier & R. Michael Gower. (2020) Fabrication of biodegradable particles with tunable morphologies by the addition of resveratrol to oil in water emulsions. International Journal of Pharmaceutics 590, pages 119917.
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Shuang Li, Jiaxin Liu, Ge Li, Xueyan Zhang, Fei Xu, Zhijiang Fu, Lesheng Teng, Youxin Li & Fengying Sun. (2019) Near-infrared light-responsive, pramipexole-loaded biodegradable PLGA microspheres for therapeutic use in Parkinson's disease. European Journal of Pharmaceutics and Biopharmaceutics 141, pages 1-11.
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Chunyan Zhang, Aiping Wang, Huiyun Wang, Maocai Yan, Rongcai Liang, Xiuting He, Fenghua Fu, Hongjie Mu & Kaoxiang Sun. (2019) Entecavir-loaded poly (lactic-co-glycolic acid) microspheres for long-term therapy of chronic hepatitis-B: Preparation and in vitro and in vivo evaluation. International Journal of Pharmaceutics 560, pages 27-34.
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Stavroula Nanaki, Panagiotis Barmpalexis, Alexandros Iatrou, Evi Christodoulou, Margaritis Kostoglou & Dimitrios Bikiaris. (2018) Risperidone Controlled Release Microspheres Based on Poly(Lactic Acid)-Poly(Propylene Adipate) Novel Polymer Blends Appropriate for Long Acting Injectable Formulations. Pharmaceutics 10:3, pages 130.
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Chenguang Pu, Qiao Wang, Hongjuan Zhang, Jingxin Gou, Yuting Guo, Xinyi Tan, Bin Xie, Na Yin, Haibing He, Yu Zhang, Yanjiao Wang, Tian Yin & Xing Tang. (2017) In Vitro-In Vivo Relationship of Amorphous Insoluble API (Progesterone) in PLGA Microspheres. Pharmaceutical Research 34:12, pages 2787-2797.
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Jinlong Zhao, Lexi Wang, Chunyu Fan, Kongtong Yu, Ximing Liu, Xiaolei Zhao, Dan Wang, Wenhua Liu, Zhengxing Su, Fengying Sun & Youxin Li. (2017) Development of near zero-order release PLGA-based microspheres of a novel antipsychotic. International Journal of Pharmaceutics 516:1-2, pages 32-38.
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Imran Vhora, Sushilkumar Patil, Hinal Patel, Jitendra Amrutiya, Rohan Lalani & Ambikanandan Misra. 2016. Handbook of Polyester Drug Delivery Systems. Handbook of Polyester Drug Delivery Systems 291 351 .
Ying Lu, Michael Sturek & Kinam Park. (2014) Microparticles produced by the hydrogel template method for sustained drug delivery. International Journal of Pharmaceutics 461:1-2, pages 258-269.
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Eun Ji Park, Sarmila Amatya, Myung Sun Kim, Jong Hoon Park, Eunyoung Seol, Heeyong Lee, Young-Hee Shin & Dong Hee Na. (2013) Long-acting injectable formulations of antipsychotic drugs for the treatment of schizophrenia. Archives of Pharmacal Research 36:6, pages 651-659.
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Guo Qiang Jiang, Yu Jie Wang & Fu Xin Ding. (2013) Thermosensitive Hydrogel Incorporating Microspheres for Injectable Implant Delivery of Naltrexone. Advanced Materials Research 647, pages 71-79.
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Matcheri S KeshavanLarry Alphs. 2012. Pharmacological Treatments in Schizophrenia. Pharmacological Treatments in Schizophrenia 50 65 .
Lexi Wang, Aiping Wang, Xiaolei Zhao, Ximing Liu, Dan Wang, Fengying Sun & Youxin Li. (2012) Design of a long-term antipsychotic in situ forming implant and its release control method and mechanism. International Journal of Pharmaceutics 427:2, pages 284-292.
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