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Research Article

The Evaluation of Lyophilized Polymer Matrices for Administering Recombinant Human Bone Morphogenetic Protein-2

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Pages 165-174 | Received 14 Sep 1995, Accepted 04 Mar 1996, Published online: 27 Sep 2008

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Read on this site (4)

Jay A. Schrier & Patrick P. DeLuca. (1999) Recombinant Human Bone Morphogenetic Protein-2 Binding and Incorporation in PLGA Microsphere Delivery Systems. Pharmaceutical Development and Technology 4:4, pages 611-621.
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Wolfgang Friess, Hasan Uludag, Shannon Foskett & Robert Biron. (1999) Bone Regeneration with Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) Using Absorbable Collagen Sponges (ACS): Influence of Processing on ACS Characteristics and Formulation. Pharmaceutical Development and Technology 4:3, pages 387-396.
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Wei Ping Ye, Yong Xu & Fu Sheng Du. (1999) The Properties of Polyesteramide and the Effects on the Stability of Bovine Serum Albumin. Pharmaceutical Development and Technology 4:1, pages 97-106.
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Rajeev Jain, Navnit H. Shah, A. Waseem Malick & Christopher T. Rhodes. (1998) Controlled Drug Delivery by Biodegradable Poly(Ester) Devices: Different Preparative Approaches. Drug Development and Industrial Pharmacy 24:8, pages 703-727.
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Articles from other publishers (16)

Melanie Coathup, Charlie Campion & Gordon Blunn. (2019) A carboxymethyl cellulose bone graft carrier delays early bone healing in an ovine model. Journal of Biomedical Materials Research Part B: Applied Biomaterials 108:3, pages 612-618.
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Ayumi Sakamoto, Pan Qi, Shinsuke Ohba, Seiichi Ohta, Yuichi Hara, Takayuki Ogawa, Masahiro Tomokiyo, Akari Sasaki, Harue Takizawa, Manabu Mochizuki, Taichi Ito & Muneki Honnami. (2018) Bone regeneration by calcium phosphate‐loaded carboxymethyl cellulose nonwoven sheets in canine femoral condyle defects. Journal of Biomedical Materials Research Part B: Applied Biomaterials 107:5, pages 1516-1521.
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Lu Zhou, Sun Jung Yoon, Kyu Yun Jang, Young Jae Moon, Sajeev Wagle, Kwang Bok Lee, Byung-Hyun Park & Jung Ryul Kim. (2014) COMP-Angiopoietin1 Potentiates the Effects of Bone Morphogenic Protein-2 on Ischemic Necrosis of the Femoral Head in Rats. PLoS ONE 9:10, pages e110593.
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Noel Davison, Huipin Yuan, Joost D. de Bruijn & Florence Barrere-de Groot. (2012) In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers. Acta Biomaterialia 8:7, pages 2759-2769.
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Hermann Agis, Benedict Beirer, Georg Watzek & Reinhard Gruber. (2010) Effects of carboxymethylcellulose and hydroxypropylmethylcellulose on the differentiation and activity of osteoclasts and osteoblasts. Journal of Biomedical Materials Research Part A 95A:2, pages 504-509.
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Zarana S. Patel, Simon Young, Yasuhiko Tabata, John A. Jansen, Mark E.K. Wong & Antonios G. Mikos. (2008) Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone 43:5, pages 931-940.
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Mark A. Reynolds, Mary E. Aichelmann-Reidy, James D. Kassolis, Hari S. Prasad & Michael D. Rohrer. (2007) Calcium sulfate–carboxymethylcellulose bone graft binder: Histologic and morphometric evaluation in a critical size defect. Journal of Biomedical Materials Research Part B: Applied Biomaterials 83B:2, pages 451-458.
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Stephen D. Cook, Samantha L. Salkeld & Laura P. Patron. (2005) Bone defect healing with an osteogenic protein-1 device combined with carboxymethylcellulose. Journal of Biomedical Materials Research Part B: Applied Biomaterials 75B:1, pages 137-145.
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Michelle D. Kofron & Cato T. Laurencin. (2004) Development of a calcium phosphate co-precipitate/poly(lactide-co-glycolide) DNA delivery system: release kinetics and cellular transfection studies. Biomaterials 25:13, pages 2637-2643.
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Maryellen Sandor, Joshua Harris & Edith Mathiowitz. (2002) A novel polyethylene depot device for the study of PLGA and P(FASA) microspheres in vitro and in vivo. Biomaterials 23:22, pages 4413-4423.
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Tetsuo Hoshino, Kazuhiro Saito, Hiroya Muranishi, Takashi Sohda & Yasuaki Ogawa. (2001) Sustained‐release microcapsules of a bone formation stimulant, TAK‐778, for local injection into a fracture site. Journal of Pharmaceutical Sciences 90:12, pages 2121-2130.
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Maryellen Sandor, David Enscore, Paula Weston & Edith Mathiowitz. (2001) Effect of protein molecular weight on release from micron-sized PLGA microspheres. Journal of Controlled Release 76:3, pages 297-311.
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Jay A. Schrier, Betsy F. Fink, Janet B. Rodgers, Henry C. Vasconez & Patrick P. DeLuca. (2001) Effect of a freeze-dried CMC/PLGA microsphere matrix of rhBMP-2 on bone healing. AAPS PharmSciTech 2:3, pages 73-80.
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Jay A. Schrier & Patrick P. DeLuca. (2001) Porous bone morphogenetic protein-2 microspheres: Polymer binding and in vitro release. AAPS PharmSciTech 2:3, pages 66-72.
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Rajeev A Jain. (2000) The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21:23, pages 2475-2490.
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D. A. Puleo, W. W. Huh, S. S. Duggirala & P. P. DeLuca. (1998) In vitro cellular responses to bioerodible particles loaded with recombinant human bone morphogenetic protein-2. Journal of Biomedical Materials Research 41:1, pages 104-110.
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