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Pharmaceutical Development and Technology Volume 2, 1997 - Issue 1
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Research Article

Effect of Particle Morphology on Emitted Dose of Fatty Acid-Treated Disodium Cromoglycate Powder Aerosols

Kristen A. Fults Departments of Pharmaceutics and Pharmacodynamics, University of Illinois at Chicago, Chicago, Illinois, 60612
,
Irving F. Miller Department of Chemical, Engineering University of Illinois at Chicago, Chicago, Illinois, 60612
&
Anthony J. Hickey Departments of Pharmaceutics and Pharmacodynamics, University of Illinois at Chicago, Chicago, Illinois, 60612
Pages 67-79 | Received 15 Aug 1996, Accepted 19 Nov 1996, Published online: 27 Sep 2008

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Heba F. Salem, Rasha M. Kharshoum, Lekaa F. Abdel Hakim & Mohamed E. Abdelrahim. (2016) Edge activators and a polycationic polymer enhance the formulation of porous voriconazole nanoagglomerate for the use as a dry powder inhaler. Journal of Liposome Research 26:4, pages 324-335.
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HF Salem, ME Abdelrahim, K Abo Eid & MA Sharaf. (2011) Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. International Journal of Nanomedicine 6, pages 311-320.
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Zhen Xu, HeidiM. Mansour & AnthonyJ. Hickey. (2011) Particle Interactions in Dry Powder Inhaler Unit Processes: A Review. Journal of Adhesion Science and Technology 25:4-5, pages 451-482.
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Hak-Kim Chan. (2003) Inhalation drug delivery devices and emerging technologies. Expert Opinion on Therapeutic Patents 13:9, pages 1333-1343.
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Abhinav Ram Mohan, Qiang Wang, Sneha Dhapare, Elizabeth Bielski, Anubhav Kaviratna, Liangfeng Han, Susan Boc & Bryan Newman. (2022) Advancements in the Design and Development of Dry Powder Inhalers and Potential Implications for Generic Development. Pharmaceutics 14:11, pages 2495.
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Riya Mahar, Arpita Chakraborty & Nidhi Nainwal. (2022) The influence of carrier type, physical characteristics, and blending techniques on the performance of dry powder inhalers. Journal of Drug Delivery Science and Technology 76, pages 103759.
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You Xu, Aneesh Thakur, Yibang Zhang & Camilla Foged. (2021) Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects. Pharmaceutics 13:2, pages 177.
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Lihi Shachar-Berman, Yan Ostrovski, Kenichiro Koshiyama, Shigeo Wada, Stavros C. Kassinos & Josué Sznitman. (2019) Targeting inhaled fibers to the pulmonary acinus: Opportunities for augmented delivery from in silico simulations. European Journal of Pharmaceutical Sciences 137, pages 105003.
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Martin W. Jetzer, Marcel Schneider, Bradley D. Morrical & Georgios Imanidis. (2018) Investigations on the Mechanism of Magnesium Stearate to Modify Aerosol Performance in Dry Powder Inhaled Formulations. Journal of Pharmaceutical Sciences 107:4, pages 984-998.
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Mohammad A.M. Momin, Ian G. Tucker, Colin S. Doyle, John A. Denman, Shubhra Sinha & Shyamal C. Das. (2018) Co-spray drying of hygroscopic kanamycin with the hydrophobic drug rifampicin to improve the aerosolization of kanamycin powder for treating respiratory infections. International Journal of Pharmaceutics 541:1-2, pages 26-36.
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Anthony J. Hickey & David A. Edwards. (2018) Density and Shape Factor Terms in Stokes' Equation for Aerodynamic Behavior of Aerosols. Journal of Pharmaceutical Sciences 107:3, pages 794-796.
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Anthony J. Hickey. (2018) Complexity in Pharmaceutical Powders for Inhalation: A perspective. KONA Powder and Particle Journal 35:0, pages 3-13.
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Anthony J. Hickey & Stefano GiovagnoliAnthony J. Hickey & Stefano Giovagnoli. 2018. Pharmaceutical Powder and Particles. Pharmaceutical Powder and Particles 55 60 .
Waseem Kaialy. (2016) On the effects of blending, physicochemical properties, and their interactions on the performance of carrier-based dry powders for inhalation — A review. Advances in Colloid and Interface Science 235, pages 70-89.
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Anthony J. Hickey. 2016. Drug Delivery. Drug Delivery 186 206 .
Shuguang Hou, Jiangyue Wu, Xu Li & Hong Shu. (2015) Practical, regulatory and clinical considerations for development of inhalation drug products. Asian Journal of Pharmaceutical Sciences 10:6, pages 490-500.
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Waseem Kaialy & Ali Nokhodchi. 2015. Pulmonary Drug Delivery. Pulmonary Drug Delivery 171 198 .
Deepak J. SinghRajesh R. JainP. S. SoniSamad AbdulHegde DarshanaRajiv V. GaikwadMala D. Menon. (2015) Preparation and Evaluation of Surface Modified Lactose Particles for Improved Performance of Fluticasone Propionate Dry Powder Inhaler. Journal of Aerosol Medicine and Pulmonary Drug Delivery 28:4, pages 254-267.
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Anne Marie Healy, Maria Inês Amaro, Krzysztof J. Paluch & Lidia Tajber. (2014) Dry powders for oral inhalation free of lactose carrier particles. Advanced Drug Delivery Reviews 75, pages 32-52.
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Wallace P. Adams, Sau L. Lee, Robert Plourde, Robert A. Lionberger, Craig M. Bertha, William H. Doub, Jean-Marc Bovet & Anthony J. Hickey. (2012) Effects of Device and Formulation on In Vitro Performance of Dry Powder Inhalers. The AAPS Journal 14:3, pages 400-409.
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Janne Raula, Matti Lehtimäki, Maarit Karppinen, Maxim Antopolsky, Hua Jiang, Antti Rahikkala & Esko I. Kauppinen. (2012) Preparation of amino acid nanoparticles at varying saturation conditions in an aerosol flow reactor. Journal of Nanoparticle Research 14:7.
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Waseem Kaialy, Martyn D. Ticehurst, John Murphy & Ali Nokhodchi. (2011) Improved Aerosolization Performance of Salbutamol Sulfate Formulated with Lactose Crystallized from Binary Mixtures of Ethanol—Acetone. Journal of Pharmaceutical Sciences 100:7, pages 2665-2684.
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Raymond Lau, Meer Saiful Hassan, Wenyin Wong & Tao Chen. (2010) Revisit of the Wall Effect on the Settling of Cylindrical Particles in the Inertial Regime. Industrial & Engineering Chemistry Research 49:18, pages 8870-8876.
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Waseem Kaialy, Mohammed N. Momin, Martyn D. Ticehurst, John Murphy & Ali Nokhodchi. (2010) Engineered mannitol as an alternative carrier to enhance deep lung penetration of salbutamol sulphate from dry powder inhaler. Colloids and Surfaces B: Biointerfaces 79:2, pages 345-356.
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Hamed Hamishehkar, Jaber Emami, Abdolhossien Rouholamini Najafabadi, Kambiz Gilani, Mohsen Minaiyan, Hamid Mahdavi & Ali Nokhodchi. (2010) Effect of carrier morphology and surface characteristics on the development of respirable PLGA microcapsules for sustained-release pulmonary delivery of insulin. International Journal of Pharmaceutics 389:1-2, pages 74-85.
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Meer Saiful Hassan & Raymond Wai Man Lau. (2009) Effect of Particle Shape on Dry Particle Inhalation: Study of Flowability, Aerosolization, and Deposition Properties. AAPS PharmSciTech 10:4.
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Sau Lawrence Lee, Wallace P. Adams, Bing V. Li, Dale P. Conner, Badrul A. Chowdhury & Lawrence X. Yu. (2009) In Vitro Considerations to Support Bioequivalence of Locally Acting Drugs in Dry Powder Inhalers for Lung Diseases. The AAPS Journal 11:3, pages 414-423.
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Lucila Garcia-ContrerasYun-Ling WongPavan MuttilDanielle PadillaJerry SadoffJessica DeRousseWillem Andreas GermishuizenSunali Goonesekera, Katharina ElbertBarry R. Bloom, Rich Miller, P. Bernard FourieAnthony HickeyDavid Edwards. (2008) Immunization by a bacterial aerosol. Proceedings of the National Academy of Sciences 105:12, pages 4656-4660.
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Nora Y.K. Chew, Boris Y. Shekunov, Henry H.Y. Tong, Albert H.L. Chow, Charles Savage, James Wu & Hak-Kim Chan. (2005) Effect of Amino Acids on the Dispersion of Disodium Cromoglycate Powders. Journal of Pharmaceutical Sciences 94:10, pages 2289-2300.
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Hiroaki Todo, Kotaro Iida, Hirokazu Okamoto & Kazumi Danjo. (2003) Improvement of Insulin Absorption from Intratracheally Administrated Dry Powder Prepared by Supercritical Carbon Dioxide Process. Journal of Pharmaceutical Sciences 92:12, pages 2475-2486.
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Ralph Niven. 2003. Pharmaceutical Inhalation Aerosol Technology, Second Edition. Pharmaceutical Inhalation Aerosol Technology, Second Edition.
Hak-Kim Chan & Nora Y.K. Chew. (2003) Novel alternative methods for the delivery of drugs for the treatment of asthma. Advanced Drug Delivery Reviews 55:7, pages 793-805.
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Timothy Crowder. 2003. A Guide to Pharmaceutical Particulate Science. A Guide to Pharmaceutical Particulate Science.
Kazuhiko Ikegami, Yoshiaki Kawashima, Hirofumi Takeuchi, Hiromitsu Yamamoto, Kazuki Mimura, Den-ichi Momose & Kiyohisa Ouchi. (2003) A new agglomerated KSR-592 β-form crystal system for dry powder inhalation formulation to improve inhalation performance in vitro and in vivo. Journal of Controlled Release 88:1, pages 23-33.
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Cynthia J. Musante, Jeffry D. Schroeter, Jacky A. Rosati, Timothy M. Crowder, Anthony J. Hickey & Ted B. Martonen. (2002) Factors Affecting the Deposition of Inhaled Porous Drug Particles. Journal of Pharmaceutical Sciences 91:7, pages 1590-1600.
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Xian‐Ming Zeng, Gary P. Martin, Christopher Marriott & John Pritchard. (2001) Lactose as a carrier in dry powder formulations: The influence of surface characteristics on drug delivery. Journal of Pharmaceutical Sciences 90:9, pages 1424-1434.
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