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Amyloid
The Journal of Protein Folding Disorders
Volume 7, 2000 - Issue 1
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Original Article

Hereditary cystatin C amyloid angiopathy

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Pages 70-79 | Received 30 Nov 1999, Accepted 20 Dec 1999, Published online: 06 Jul 2009

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Read on this site (8)

Jianwei He, Linan Xu, Zhiyuan Zou, Nobuhiro Ueyama, Hui Li, Akio Kato, Gary W. Jones & Youtao Song. (2013) Molecular dynamics simulation to investigate the impact of disulfide bond formation on conformational stability of chicken cystatin I66Q mutant. Journal of Biomolecular Structure and Dynamics 31:10, pages 1101-1110.
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Yuanyuan Yu, Xin Liu, Jianwei He, Mengyuan Zhang, Hui Li, Dongqing Wei & Youtao Song. (2012) Appendant structure plays an important role in amyloidogenic cystatin dimerization prior to domain swapping. Journal of Biomolecular Structure and Dynamics 30:1, pages 102-112.
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Gustav Östner, Veronica Lindström, Alexander B. Postnikov, Tatiana I. Solovyeva, Össur I. Emilsson & Anders Grubb. (2011) High throughput testing of drug library substances and monoclonal antibodies for capacity to reduce formation of cystatin C dimers to identify candidates for treatment of hereditary cystatin C amyloid angiopathy. Scandinavian Journal of Clinical and Laboratory Investigation 71:8, pages 676-682.
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Yuanyuan Yu, Yaofeng Wang, Jianwei He, Yuan Liu, Hui Li, Huili Zhang & Youtao Song. (2010) Structural and Dynamic properties of a new Amyloidogenic chicken cystatin Mutant I108T. Journal of Biomolecular Structure and Dynamics 27:5, pages 641-649.
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Hsuan-Liang Liu, Yuan-Min Lin, Jian-Hua Zhao, Man-Ching Hsieh, Hsin-Yi Lin, Chih-Hung Huang, Hsu-Wei Fang, Yih Ho & Wen-Yih Chen. (2007) Molecular Dynamics Simulations of Human Cystatin C and Its L68Q Varient to Investigate the Domain Swapping Mechanism. Journal of Biomolecular Structure and Dynamics 25:2, pages 135-144.
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M. L. Selenica, X. Wang, L. Ostergaard‐Pedersen, A. Westlind‐Danielsson & A. Grubb. (2007) Cystatin C reduces the in vitro formation of soluble Aβ1‐42 oligomers and protofibrils. Scandinavian Journal of Clinical and Laboratory Investigation 67:2, pages 179-190.
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Michele Mussap & Mario Plebani. (2004) Biochemistry and Clinical Role of Human Cystatin C. Critical Reviews in Clinical Laboratory Sciences 41:5-6, pages 467-550.
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Maria Bjarnadottir, Carol Nilsson, Veronica Lindstrom, Ann Westman, Pia Davidsson, Finnbogi Thormodsson, Hannes Blondal, Gunnar Gudmundsson & Anders Grubb. (2001) The cerebral hemorrhage-producing cystatin C variant (L68Q) in extracellular fluids. Amyloid 8:1, pages 1-10.
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Adriana Żyła, Anne Martel, Przemysław Jurczak, Augustyn Moliński, Aneta Szymańska & Maciej Kozak. (2023) Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view. Scientific Reports 13:1.
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Gargi Banerjee, John Collinge, Nick C Fox, Tammaryn Lashley, Simon Mead, Jonathan M Schott, David J Werring & Natalie S Ryan. (2023) Clinical considerations in early-onset cerebral amyloid angiopathy. Brain.
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Emilia Iłowska, Jakub Barciszewski, Mariusz Jaskólski, Augustyn Moliński, Maciej Kozak & Aneta Szymańska. (2022) Identification of a Steric Zipper Motif in the Amyloidogenic Core of Human Cystatin C and Its Use for the Design of Self-Assembling Peptides. International Journal of Molecular Sciences 23:10, pages 5800.
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James Frederick Meschia & Myriam Fornage. 2022. Stroke. Stroke 237 246.e4 .
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Ryan Brown, Sridesh Nath, Alnardo Lora, Ghassan Samaha, Ziyad Elgamal, Ryan Kaiser, Clifford Taggart, Sinéad Weldon & Patrick Geraghty. (2020) Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics. Respiratory Research 21:1.
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Martyna Maszota‐Zieleniak, Przemyslaw Jurczak, Marta Orlikowska, Igor Zhukov, Dominika Borek, Zbyszek Otwinowski, Piotr Skowron, Zuzanna Pietralik, Maciej Kozak, Aneta Szymańska & Sylwia Rodziewicz‐Motowidło. (2019) NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution . The FEBS Journal 287:2, pages 361-376.
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M. Rafalik, M. Spodzieja, A.S. Kołodziejczyk, S. Rodziewicz-Motowidło, A. Szymańska, A. Grubb & P. Czaplewska. (2019) The identification of discontinuous epitope in the human cystatin C – Monoclonal antibody HCC3 complex. Journal of Proteomics 191, pages 58-67.
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Emilia Iłowska, Justyna Sawicka & Aneta Szymańska. (2018) Synthesis and physicochemical studies of amyloidogenic hexapeptides derived from human cystatin C. Journal of Peptide Science 24:4-5.
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Magdalena Murawska, Aneta Szymańska, Anders Grubb & Maciej Kozak. (2017) Overall conformation of covalently stabilized domain-swapped dimer of human cystatin C in solution. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 411, pages 136-140.
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Anas Shamsi & Bilqees Bano. (2017) Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions. International Journal of Biological Macromolecules 102, pages 674-693.
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Martyna Prądzińska, Izabela Behrendt, Juan Astorga-Wells, Aleksandr Manoilov, Roman A. Zubarev, Aleksandra S. Kołodziejczyk, Sylwia Rodziewicz-Motowidło & Paulina Czaplewska. (2016) Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C. Amino Acids 48:12, pages 2809-2820.
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Tyler J. Perlenfein & Regina M. Murphy. (2016) Expression, purification, and characterization of human cystatin C monomers and oligomers. Protein Expression and Purification 117, pages 35-43.
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Shijie Liu. (2015) A review on protein oligomerization process. International Journal of Precision Engineering and Manufacturing 16:13, pages 2731-2760.
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Paraskevi L. Tsiolaki, Nikolaos N. Louros, Stavros J. Hamodrakas & Vassiliki A. Iconomidou. (2015) Exploring the ‘aggregation-prone’ core of human Cystatin C: A structural study. Journal of Structural Biology 191:3, pages 272-280.
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Paraskevi L. Tsiolaki, Stavros J. Hamodrakas & Vassiliki A. Iconomidou. (2014) The pentapeptide LQVVR plays a pivotal role in human cystatin C fibrillization. FEBS Letters 589:1, pages 159-164.
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J-T Kim, S-J Lee, M A Kang, J E Park, B-Y Kim, D-Y Yoon, Y Yang, C-H Lee, Y I Yeom, Y-K Choe & H G Lee. (2013) Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity. Cell Death & Disease 4:12, pages e974-e974.
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