Citations (42)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
M. Pehrsson, M. S. Alexdóttir, M. A. Karsdal, P. Thakker & J.H. Mortensen. (2023) Novel fibro-inflammatory biomarkers associated with disease activity in patients with Crohn’s disease. Expert Review of Gastroenterology & Hepatology 17:6, pages 575-587.
Read now
Read now
Diana J. Leeming, Sanne S. Veidal, Morten A. Karsdal, Mette Juul Nielsen, Jonel Trebicka, Troels Busk, Flemming Bendtsen, Aleksander Krag & Søren Møller. (2015) Pro-C5, a marker of true type V collagen formation and fibrillation, correlates with portal hypertension in patients with alcoholic cirrhosis. Scandinavian Journal of Gastroenterology 50:5, pages 584-592.
Read now
Read now
Morten A. Karsdal, Anne Christine Bay-Jensen, Diana Julie Leeming, Kim Henriksen & Claus Christiansen. (2013) Quantification of “end products” of tissue destruction in inflammation may reflect convergence of cytokine and signaling pathways – implications for modern clinical chemistry. Biomarkers 18:5, pages 375-378.
Read now
Read now
Articles from other publishers (39)
Martin Pehrsson, Willemijn E. de Rooij, Anne-Christine Bay-Jensen, Morten Asser Karsdal, Joachim Høg Mortensen & Albert Jan Bredenoord. (2023) Extracellular matrix remodeling proteins as biomarkers for clinical assessment and treatment outcomes in eosinophilic esophagitis. BMC Gastroenterology 23:1.
Crossref
Crossref
Neel I. Nissen, Astrid Z. Johansen, Inna M. Chen, Christina Jensen, Emilie A. Madsen, Carsten P. Hansen, Jeppe Thorlacius-Ussing, Morten Karsdal, Julia S. Johansen, Hadi M. H. Diab, Lars N. Jørgensen & Nicholas Willumsen. (2023) High serum levels of the C-propetide of type V collagen (PRO-C5) are prognostic for short overall survival in patients with pancreatic ductal adenocarcinoma. Frontiers in Molecular Biosciences 10.
Crossref
Crossref
Viktor Domislovic, Joachim Høg Mortensen, Majken Lindholm, Morten Asser Kaarsdal, Marko Brinar, Ana Barisic, Tina Manon-Jensen & Zeljko Krznaric. (2022) Inflammatory Biomarkers of Extracellular Matrix Remodeling and Disease Activity in Crohn’s Disease and Ulcerative Colitis. Journal of Clinical Medicine 11:19, pages 5907.
Crossref
Crossref
Rucsandra Dobrota, Suzana Jordan, Pernille Juhl, Britta Maurer, Lukas Wildi, Anne-Christine Bay-Jensen, Morten Asser Karsdal, Ariane L Herrick, Jörg H W Distler, Yannick Allanore, Anna-Maria Hoffmann-Vold, Anne Sofie Siebuhr & Oliver Distler. (2021) Circulating collagen neo-epitopes and their role in the prediction of fibrosis in patients with systemic sclerosis: a multicentre cohort study. The Lancet Rheumatology 3:3, pages e175-e184.
Crossref
Crossref
Marcus Fager Ferrari, Eva Zetterberg, Maria Rossing, Tina Manon‐Jensen, Martin Pehrsson, Morten A. Karsdal, Jens Lykkesfeldt & Eva Leinoe. (2020) Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes. Haemophilia 27:1.
Crossref
Crossref
Sarah Rank Rønnow, Rand Qais Dabbagh, Federica Genovese, Carmel B. Nanthakumar, Vikki J. Barrett, Robert B. Good, Sarah Brockbank, Simon Cruwys, Henrik Jessen, Grith Lykke Sorensen, Morten Asser Karsdal, Diana Julie Leeming & Jannie Marie Bülow Sand. (2020) Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis. Respiratory Research 21:1.
Crossref
Crossref
Pernille Juhl, Sandie Bondesen, Clare Louise Hawkins, Morten Asser Karsdal, Anne-Christine Bay-Jensen, Michael Jonathan Davies & Anne Sofie Siebuhr. (2020) Dermal fibroblasts have different extracellular matrix profiles induced by TGF-β, PDGF and IL-6 in a model for skin fibrosis. Scientific Reports 10:1.
Crossref
Crossref
Michelle L. Boland, Rhianna C. Laker, Karly Mather, Arkadiusz Nawrocki, Stephanie Oldham, Brandon B. Boland, Hilary Lewis, James Conway, Jacqueline Naylor, Silvia Guionaud, Michael Feigh, Sanne S. Veidal, Louise Lantier, Owen P. McGuinness, Joseph Grimsby, Cristina M. Rondinone, Lutz Jermutus, Martin R. Larsen, James L. Trevaskis & Christopher J. Rhodes. (2020) Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis. Nature Metabolism 2:5, pages 413-431.
Crossref
Crossref
Fernando Bril, Diana Julie Leeming, Morten Asser Karsdal, Srilaxmi Kalavalapalli, Diana Barb, Jinping Lai, Matthew Rabe & Kenneth Cusi. (2019) Use of Plasma Fragments of Propeptides of Type III, V, and VI Procollagen for the Detection of Liver Fibrosis in Type 2 Diabetes. Diabetes Care 42:7, pages 1348-1351.
Crossref
Crossref
Lindsey Nicol, Patrick Morar, Ying Wang, Kim Henriksen, Shu Sun, Morten Karsdal, Rosamund Smith, Sandesh C.S. Nagamani, Jay Shapiro, Brendan Lee & Eric Orwoll. (2019) Alterations in non-type I collagen biomarkers in osteogenesis imperfecta. Bone 120, pages 70-74.
Crossref
Crossref
D.J. Leeming & M.A. Karsdal. 2019. Biochemistry of Collagens, Laminins and Elastin. Biochemistry of Collagens, Laminins and Elastin
51
57
.
Pernille Juhl, Anne-Christine Bay-Jensen, Morten Karsdal, Anne Sofie Siebuhr, Nathalie Franchimont & Juan Chavez. (2018) Serum biomarkers of collagen turnover as potential diagnostic tools in diffuse systemic sclerosis: A cross-sectional study. PLOS ONE 13:12, pages e0207324.
Crossref
Crossref
L. Lorentzen, N. A. Henriksen, P. Juhl, J. H. Mortensen, M. S. Ågren, M. A. Karsdal & L. N. Jorgensen. (2018) Type V Collagen is Persistently Altered After Inguinal Hernia Repair. Scandinavian Journal of Surgery 107:3, pages 212-217.
Crossref
Crossref
Joachim Høg Mortensen, Tina Manon-Jensen, Michael Dam Jensen, Per Hägglund, Lone Gabriels Klinge, Jens Kjeldsen, Aleksander Krag, Morten Asser Karsdal & Anne-Christine Bay-Jensen. (2017) Ulcerative colitis, Crohn’s disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn’s disease. PLOS ONE 12:10, pages e0185855.
Crossref
Crossref
W. T. van Haaften, J. H. Mortensen, M. A. Karsdal, A. C. Bay-Jensen, G. Dijkstra & P. Olinga. (2017) Misbalance in type III collagen formation/degradation as a novel serological biomarker for penetrating (Montreal B3) Crohn's disease. Alimentary Pharmacology & Therapeutics 46:1, pages 26-39.
Crossref
Crossref
T. Manon‐Jensen, M.A. Karsdal, L.N. Nielsen, M. Kjelgaard‐Hansen, B. Vandahl, E.H.N. Olsen, M. Enoksson & K. Roepstorff. (2016) Altered collagen turnover in factor VIII‐deficient rats with hemophilic arthropathy identifies potential novel serological biomarkers in hemophilia. Journal of Thrombosis and Haemostasis 14:12, pages 2419-2429.
Crossref
Crossref
Nadia A. Henriksen, Joachim H. Mortensen, Lea Lorentzen, Magnus S. Ågren, Anne C. Bay-Jensen, Lars N. Jorgensen & Morten A. Karsdal. (2016) Abdominal wall hernias—A local manifestation of systemically impaired quality of the extracellular matrix. Surgery 160:1, pages 220-227.
Crossref
Crossref
Ki M. Mak, Chien Yi M. Png & Danielle J. Lee. (2016) Type V Collagen in Health, Disease, and Fibrosis. The Anatomical Record 299:5, pages 613-629.
Crossref
Crossref
Morten A. Karsdal, Federica Genovese, Emilie A. Madsen, Tina Manon-Jensen & Detlef Schuppan. (2016) Collagen and tissue turnover as a function of age: Implications for fibrosis. Journal of Hepatology 64:1, pages 103-109.
Crossref
Crossref
D.J. Leeming & M.A. Karsdal. 2016. Biochemistry of Collagens, Laminins and Elastin. Biochemistry of Collagens, Laminins and Elastin
43
48
.
N.U.B. Hansen, F. Genovese, D.J. Leeming & M.A. Karsdal. (2015) The importance of extracellular matrix for cell function and in vivo likeness. Experimental and Molecular Pathology 98:2, pages 286-294.
Crossref
Crossref
Nadia A. Henriksen, Joachim H. Mortensen, Lars T. Sorensen, Anne C. Bay-Jensen, Magnus S. Ågren, Lars N. Jorgensen & Morten A. Karsdal. (2015) The collagen turnover profile is altered in patients with inguinal and incisional hernia. Surgery 157:2, pages 312-321.
Crossref
Crossref
M. A. Karsdal, H. Krarup, J. M. B. Sand, P. B. Christensen, J. Gerstoft, D. J. Leeming, N. Weis, O. B. Schaffalitzky de Muckadell & A. Krag. (2014) Review article: the efficacy of biomarkers in chronic fibroproliferative diseases - early diagnosis and prognosis, with liver fibrosis as an exemplar. Alimentary Pharmacology & Therapeutics 40:3, pages 233-249.
Crossref
Crossref
Shizuka Hirai, Chie OhyaneYoung-Il KimShan LinTsuyoshi GotoNobuyuki TakahashiChu-Sook Kim, Jihey Kang, Rina Yu & Teruo Kawada. (2014) Involvement of mast cells in adipose tissue fibrosis. American Journal of Physiology-Endocrinology and Metabolism 306:3, pages E247-E255.
Crossref
Crossref
Jacob Hull Kristensen, Morten Asser Karsdal, Federica Genovese, Simon Johnson, Birte Svensson, Susanne Jacobsen, Per Hägglund & Diana Julie Leeming. (2014) The Role of Extracellular Matrix Quality in Pulmonary Fibrosis. Respiration 88:6, pages 487-499.
Crossref
Crossref
Ariel Bing-Shi Tan, Sebastian Kress, Leticia Castro, Allan Sheppard & Michael Raghunath. (2013) Cellular re- and de-programming by microenvironmental memory: why short TGF-β1 pulses can have long effects. Fibrogenesis & Tissue Repair 6:1.
Crossref
Crossref
D. J. Leeming, M. A. Karsdal, I. Byrjalsen, F. Bendtsen, J. Trebicka, M. J. Nielsen, C. Christiansen, S. Møller & A. Krag. (2013) Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension. Alimentary Pharmacology & Therapeutics 38:9, pages 1086-1096.
Crossref
Crossref
Diana J. Leeming, Inger Byrjalsen, Wladimiro Jiménez, Claus Christiansen & Morten A. Karsdal. (2012) Protein fingerprinting of the extracellular matrix remodelling in a rat model of liver fibrosis—a serological evaluation. Liver International 33:3, pages 439-447.
Crossref
Crossref
Morten A. KarsdalMette J. NielsenJannie M. SandKim HenriksenFederica GenoveseAnne-Christine Bay-JensenVictoria SmithJoanne I. AdamkewiczClaus ChristiansenDiana J. Leeming. (2013)
Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue Diseases
Possibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure
. ASSAY and Drug Development Technologies 11:2, pages 70-92.
Crossref
Crossref
Anne C. Bay-Jensen, Stephanie Wichuk, Inger Byrjalsen, Diana J. Leeming, Nathalie Morency, Claus Christiansen, Morten A. Karsdal & Walter P. Maksymowych. (2013) Circulating Protein Fragments of Cartilage and Connective Tissue Degradation Are Diagnostic and Prognostic Markers of Rheumatoid Arthritis and Ankylosing Spondylitis. PLoS ONE 8:1, pages e54504.
Crossref
Crossref
Jianxia Wang, Nicholas WillumsenQinlong Zheng, Ying Xue, Morten A Karsdal & Anne C Bay-Jensen. (2013) Bringing cancer serological diagnosis to a new level: focusing on HER2, protein ectodomain shedding and neoepitope technology. Future Oncology 9:1, pages 35-44.
Crossref
Crossref
Anita V Neutzsky-Wulff, Kim V Andreassen, Sara T Hjuler, Michael Feigh, Anne-Christine Bay-Jensen, Qinlong Zheng, Kim Henriksen & Morten A Karsdal. (2012) Future detection and monitoring of diabetes may entail analysis of both β-cell function and volume: How markers of β-cell loss may assist. Journal of Translational Medicine 10:1.
Crossref
Crossref
Efstathios Vassiliadis, Lars M Rasmussen, Inger Byrjalsen, Dorthe Vang Larsen, Rajiv Chaturvedi, Susanne Hosbond, Lotte Saabye, Axel CP Diederichsen, Federica Genovese, Kevin L Duffin, Qinlong Zheng, Xiaoliang Chen, Diana J Leeming, Claus Christiansen & Morten A Karsdal. (2012) Clinical evaluation of a matrix metalloproteinase-12 cleaved fragment of titin as a cardiovascular serological biomarker. Journal of Translational Medicine 10:1.
Crossref
Crossref
Diana J. Leeming, Mette J. Nielsen, Yueqin Dai, Sanne S. Veidal, Efstathios Vassiliadis, Chen Zhang, Yi He, Ben Vainer, Qinlong Zheng & Morten A. Karsdal. (2012) Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis. Hepatology Research 42:5, pages 482-493.
Crossref
Crossref
S.S. Veidal, D.V. Larsen, X. Chen, S. Sun, Q. Zheng, A.-C. Bay-Jensen, D.J. Leeming, A. Nawrocki, M.R. Larsen, G. Schett & M.A. Karsdal. (2012) MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis. Clinical Biochemistry 45:7-8, pages 541-546.
Crossref
Crossref
Efstathios VassiliadisNatasha BarascukAthanasios DidangelosMorten A Karsdal. (2012) Novel Cardiac-Specific Biomarkers and the Cardiovascular Continuum. Biomarker Insights 7, pages BMI.S9536.
Crossref
Crossref
E. VassiliadisS.S. VeidalC. HansenM.A. KarsdalD.J. Leeming. (2012) Circulating Levels of a Collagen Type V Propeptide Fragment in a Carbon Tetrachloride Reversible Model of Liver Fibrosis. Biomarker Insights 7, pages BMI.S10975.
Crossref
Crossref
Tianhui LiuXiaoming WangMorten A. KarsdalDiana J. LeemingFederica Genovese. (2012) Molecular Serum Markers of Liver Fibrosis. Biomarker Insights 7, pages BMI.S10009.
Crossref
Crossref
Sanne S Veidal, Morten A Karsdal, Arkadiusz Nawrocki, Martin R Larsen, Yueqin Dai, Qinlong Zheng, Per Hägglund, Ben Vainer, Helene Skjøt-Arkil & Diana J Leeming. (2011) Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis. Fibrogenesis & Tissue Repair 4:1.
Crossref
Crossref