Advanced search
Publication Cover
Journal of Nutritional & Environmental Medicine Volume 5, 1995 - Issue 3
Journal homepage
21
Views
51
CrossRef citations to date
0
Altmetric
Review Article

Oxidants and Antioxidants in Clinical Medicine: Past, Present and Future Potential

Jeffrey S Bland Health Comm International Inc, Clinical Research Center, Soundview Drive, Building B, Gig Harbor, WA 98335, PO Box 1729, 5800, USA
Pages 255-280 | Published online: 13 Jul 2009

Citations (51)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

A. Kumaran & R. Joel Karunakaran. (2006) Antioxidant Activities of the Methanol Extract of Cardiospermum halicacabum.. Pharmaceutical Biology 44:2, pages 146-151.
Read now
Margaret Moss. (2001) Purines, Alcohol and Boron in the Diets of People with Chronic Digestive Problems. Journal of Nutritional & Environmental Medicine 11:1, pages 23-32.
Read now
RAM B. SINGH MD, SHANTI S. RASTOGI MD, REEMA SINGH DDPHN, MOHAMMAD A. NIAZ PHD, NAND K. SINGH MD & AND SHRI V. MADHU MD. (1997) Effects on Plasma Ascorbic Acid and Coronary Risk Factors of Adding Guava Fruit to the Usual Diet in Hypertensives with Mild to Moderate. Journal of Nutritional & Environmental Medicine 7:1, pages 5-14.
Read now
D Downing, H M Anthony, S Birtwhistle, K K Eaton, J R Mansfield, J M Meldrum & M J Radcliffe. (1996) Effective Nutritional Medicine: The Application of Nutrition to Major Health Problems: British Society for Allergy and Environmental Medicine with the British Society for Nutritional Medicine. Journal of Nutritional & Environmental Medicine 6:2, pages 191-232.
Read now

Articles from other publishers (47)

Pooja Sharma, Manisha Thakur, Shwet Kamal, Anjali Chauhan, Happy Dev & Ruchi Gupta. (2023) Transcriptome Analysis for Gaining Insight into Gingerol Biosynthesis and MAPK-Dependent Hormonal Signaling Pathway Involved in Resistance Mechanism in Fusarium Wilt Tolerant Ginger (Zingiber officinale Rosc.) Produced Through In Vitro Mutagenesis and Selection. Journal of Plant Growth Regulation.
Crossref
Muhammad Muddassir, Azra Batool, Mahboob Alam, Ghulam Abbas Miana, Reem Altaf, Saad Alghamdi, Mazen Almehmadi, Osama Abdulaziz, Ahad Amer Alsaiari, Muhammad Umar Khayam Sahibzada, Ameer Khusro & Muhammad Tariq Khan. (2022) Evaluation of in vitro, in silico antidiabetic and antioxidant potential of bioactivity based isolated “Pakistanine” from Berberis baluchistanica. Arabian Journal of Chemistry 15:11, pages 104221.
Crossref
Eugene B. Postnikov, Mariola Bartoszek, Justyna Polak & Mirosław Chorążewski. (2022) Combination of Machine Learning and Analytical Correlations for Establishing Quantitative Compliance between the Trolox Equivalent Antioxidant Capacity Values Obtained via Electron Paramagnetic Resonance and Ultraviolet–Visible Spectroscopies. International Journal of Molecular Sciences 23:19, pages 11743.
Crossref
Kolajo Adedamola Akinyede, Gail Denise Hughes, Okobi Eko Ekpo & Oluwafemi Omoniyi Oguntibeju. (2022) Comparative Study of the Antioxidant Constituents, Activities and the GC-MS Quantification and Identification of Fatty Acids of Four Selected Helichrysum Species. Plants 11:8, pages 998.
Crossref
Maximillian Taro William Lee, William Mahy & Mark David Rackham. (2021) The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health. RSC Medicinal Chemistry 12:8, pages 1281-1311.
Crossref
Ana Alves, Emília Sousa, Anake Kijjoa & Madalena Pinto. (2020) Marine-Derived Compounds with Potential Use as Cosmeceuticals and Nutricosmetics. Molecules 25:11, pages 2536.
Crossref
Jing XU, Sheng GAN, Jun LI, De-Bing WAND, Yu CHEN, Xin HU & Guang-Zhong YANG. (2017) Garcinia xanthochymus extract protects PC12 cells from H 2 O 2 -induced apoptosis through modulation of PI3K/AKT and NRF2/HO-1 pathways. Chinese Journal of Natural Medicines 15:11, pages 825-833.
Crossref
H. K. Kumara & D. Channe Gowda. (2016) Synthesis and SAR Studies of Bisthiourea Derivatives of Dipeptides Lys/lys-Asp, Lys/lys-Trp Conjugated Benzo[d]isoxazole as Promising Antioxidants. International Journal of Peptide Research and Therapeutics 23:2, pages 259-267.
Crossref
Kabo Masisi, Trust Beta & Mohammed H. Moghadasian. (2016) Antioxidant properties of diverse cereal grains: A review on in vitro and in vivo studies. Food Chemistry 196, pages 90-97.
Crossref
Zhao Yao, Yunlong Zhang, Hongyan Li, Zeyuan Deng & Xiaoping Zhang. (2015) Synergistic effect of Se-methylselenocysteine and vitamin E in ameliorating the acute ethanol-induced oxidative damage in rat. Journal of Trace Elements in Medicine and Biology 29, pages 182-187.
Crossref
Hafsa Ali, Zoya Ghori, Sandal Sheikh & Alvina Gul. 2015. Crop Production and Global Environmental Issues. Crop Production and Global Environmental Issues 27 78 .
Gokhan Zengin, Tuba Arkan, Abdurrahman Aktumsek, Gokalp Ozmen Guler & Yavuz Selim Cakmak. (2013) A Study on Antioxidant Capacities and Fatty Acid Compositions of Two Daphne Species from Turkey: New Sources of Antioxidants and Essential Fatty Acids . Journal of Food Biochemistry 37:6, pages 646-653.
Crossref
Sandra Gonçalves, Diogo Gomes, Patrícia Costa & Anabela Romano. (2013) The phenolic content and antioxidant activity of infusions from Mediterranean medicinal plants. Industrial Crops and Products 43, pages 465-471.
Crossref
A.B. Tayade, P. Dhar, M. Sharma, R.S. Chauhan, O.P. Chaurasia & R.B. Srivastava. (2013) Antioxidant Capacities, Phenolic Contents, and GC/MS Analysis of Rhodiola imbricata Edgew. Root Extracts from Trans‐Himalaya . Journal of Food Science 78:3.
Crossref
Amit Bahukhandi, Sandeep Rawat, Indra D. Bhatt & Ranbeer S. Rawal. (2013) Influence of Solvent Types and Source of Collection on Total Phenolic Content and Antioxidant Activities of Acorus calamus L.. National Academy Science Letters 36:1, pages 93-99.
Crossref
Mir Zahoor Gul, Vidya Attuluri, Insaf Ahmed Qureshi & Irfan Ahmad Ghazi. (2012) Antioxidant and α-glucosidase inhibitory activities of Murraya koenigii leaf extracts. Pharmacognosy Journal 4:32, pages 65-72.
Crossref
P. Dhar, A.B. Tayade, P.K. Bajpai, V.K. Sharma, S.K. Das, O.P. Chaurasia, R.B. Srivastava & S.B. Singh. (2012) Antioxidant Capacities and Total Polyphenol Contents of Hydro-ethanolic Extract of Phytococktail from Trans-Himalaya. Journal of Food Science 77:2, pages C156-C161.
Crossref
Mariapia Vairetti, Andrea Ferrigno, Vittoria Rizzo, Giulia Ambrosi, Alberto Bianchi, Plinio Richelmi, Fabio Blandini & Marie-Therese Armentero. (2012) Impaired hepatic function and central dopaminergic denervation in a rodent model of Parkinson's disease: A self-perpetuating crosstalk?. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1822:2, pages 176-184.
Crossref
Nor Syahida Aliahmat, Mohd Razman Mohd Noor, Wan Junizam Wan Yusof, Suzana Makpol, Wan Zurinah Wan Ngah & Yasmin Anum Mohd Yusof. (2012) Antioxidant enzyme activity and malondialdehyde levels can be modulated by Piper betle, tocotrienol rich fraction and Chlorella vulgaris in aging C57BL/6 mice. Clinics 67:12, pages 1447-1454.
Crossref
Se-Kwon KimBin Yang, Xiuping Lin, Xue-Feng Zhou, Xian Yang & Yonghong Liu. 2011. Marine Cosmeceuticals. Marine Cosmeceuticals 11 38 .
Liliana Jimenez, Emilio Alarcón, Colleen Trevithick-Sutton, Niket Gandhi & Juan C. Scaiano. (2011) Effect of γ-radiation on green onion DNA integrity: Role of ascorbic acid and polyphenols against nucleic acid damage. Food Chemistry 128:3, pages 735-741.
Crossref
Nitin K. Upadhyay, M.S. Yogendra Kumar & Asheesh Gupta. (2010) Antioxidant, cytoprotective and antibacterial effects of Sea buckthorn (Hippophae rhamnoides L.) leaves. Food and Chemical Toxicology 48:12, pages 3443-3448.
Crossref
Zai-Qun Liu. (2010) Chemical Methods To Evaluate Antioxidant Ability. Chemical Reviews 110:10, pages 5675-5691.
Crossref
Jian-Ming Lü, Peter H. Lin, Qizhi Yao & Changyi Chen. (2010) Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems. Journal of Cellular and Molecular Medicine 14:4, pages 840-860.
Crossref
Zai-Qun Liu, Xu-Yang Luo, Yun-Xiu Sun, Wei Wu, Chun-Ming Liu, Zhi-Qiang Liu & Shu-Ying Liu. (2004) The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis. Journal of Pharmacy and Pharmacology 56:12, pages 1557-1562.
Crossref
Yang Qingming, Pan Xianhui, Kong Weibao, Yang Hong, Su Yidan, Zhang Li, Zhang Yanan, Yang Yuling, Ding Lan & Liu Guoan. (2010) Antioxidant activities of malt extract from barley (Hordeum vulgare L.) toward various oxidative stress in vitro and in vivo. Food Chemistry 118:1, pages 84-89.
Crossref
Guo-Xiang Li & Zai-Qun Liu. (2009) Unusual Antioxidant Behavior of α- and γ-Terpinene in Protecting Methyl Linoleate, DNA, and Erythrocyte. Journal of Agricultural and Food Chemistry 57:9, pages 3943-3948.
Crossref
A. Dvaranauskaite, P.R. Venskutonis & J. Labokas. (2008) Comparison of Quercetin derivatives in ethanolic extracts of red raspberry (Rubus idaeus L.) leaves. Acta Alimentaria 37:4, pages 449-461.
Crossref
Maureen Benbow. (2008) Nutrition and wound healing. Independent Nurse 2008:9.
Crossref
Ting WangLixiang ChenWeimin WuYuan LongRui Wang. (2008) Potential cytoprotection: antioxidant defence by caffeic acid phenethyl ester against free radical-induced damage of lipids, DNA, and proteins. Canadian Journal of Physiology and Pharmacology 86:5, pages 279-287.
Crossref
Hai-Lan Huang, Dong-Li Li, Xiao-Ming Li, Bo Xu & Bin-Gui Wang. (2007) Antioxidative principals of Jussiaea repens: an edible medicinal plant. International Journal of Food Science & Technology 42:10, pages 1219-1227.
Crossref
Ellen Butensky, Christine M. Kennedy, Marion M. Lee, Paul Harmatz & Christine Miaskowski. (2004) Potential Mechanisms for Altered Iron Metabolism in Human Immunodeficiency Virus Disease. Journal of the Association of Nurses in AIDS care 15:6, pages 31-45.
Crossref
Yanjun Zhang, Robert H Cichewicz & Muraleedharan G Nair. (2004) Lipid peroxidation inhibitory compounds from daylily (Hemerocallis fulva) leaves. Life Sciences 75:6, pages 753-763.
Crossref
Xin Lin, Ding-Jian Yang, Wen-Qing Cai, Qian-Yu Zhao, Yan-Feng Gao, Qiang Chen & Rui Wang. (2003) Endomorphins, endogenous opioid peptides, provide antioxidant defense in the brain against free radical-induced damage. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1639:3, pages 195-202.
Crossref
Zai‐Qun Liu, Xu‐Yang Luo, Guo‐Zong Liu & Qing‐Wen Liu. (2003) Including 4‐Hydroxyquinoline Derivatives into β‐Cyclodextrin to Form Complexes Affects Their Antioxidative Effect on Free‐Radical‐Induced Hemolysis of Human Erythrocytes. QSAR & Combinatorial Science 22:8, pages 859-864.
Crossref
M. Nowak, E. Świȩtochowska, T. Wielkoszyński, B. Marek, J. Karpe, J. Górski, J. Głogowska-szelαg, B. Kos-kudła & Z. Ostrowska. (2018) Changes in Blood Antioxidants and Several Lipid Peroxidation Products in Women with Age-Related Macular Degeneration. European Journal of Ophthalmology 13:3, pages 281-286.
Crossref
Zai-Qun Liu, Xu-Yang Luo, Guo-Zong Liu, Yan-Ping Chen, Zhi-Cai Wang & Yun-Xiu Sun. (2003) In Vitro Study of the Relationship between the Structure of Ginsenoside and Its Antioxidative or Prooxidative Activity in Free Radical Induced Hemolysis of Human Erythrocytes. Journal of Agricultural and Food Chemistry 51:9, pages 2555-2558.
Crossref
Yu-Jun Cai, Jin-Qiu Dai, Jian-Guo Fang, Lan-Ping Ma, Li-Fen Hou, Li Yang & Zhong-Li Liu. (2002) Antioxidative and free radical scavenging effects of ecdysteroids from Serratula strangulata . Canadian Journal of Physiology and Pharmacology 80:12, pages 1187-1194.
Crossref
Yu-Jun Cai, Lan-Ping Ma, Li-Fen Hou, Bo Zhou, Li Yang & Zhong-Li Liu. (2002) Antioxidant effects of green tea polyphenols on free radical initiated peroxidation of rat liver microsomes. Chemistry and Physics of Lipids 120:1-2, pages 109-117.
Crossref
Zai-Qun Liu, Xu-Yang Luo, Yun-Xiu Sun, Yan-Ping Chen & Zhi-Cai Wang. (2002) Can ginsenosides protect human erythrocytes against free-radical-induced hemolysis?. Biochimica et Biophysica Acta (BBA) - General Subjects 1572:1, pages 58-66.
Crossref
Zai-Qun Liu, Kun Han, Ying-Jie Lin & Xu-Yang Luo. (2002) Antioxidative or prooxidative effect of 4-hydroxyquinoline derivatives on free-radical-initiated hemolysis of erythrocytes is due to its distributive status. Biochimica et Biophysica Acta (BBA) - General Subjects 1570:2, pages 97-103.
Crossref
Robert H. Cichewicz & Muraleedharan G. Nair. (2001) Isolation and Characterization of Stelladerol, a New Antioxidant Naphthalene Glycoside, and Other Antioxidant Glycosides from Edible Daylily ( Hemerocallis ) Flowers . Journal of Agricultural and Food Chemistry 50:1, pages 87-91.
Crossref
Luis Bergues Cabrales, Héctor Camué Ciria, Rodolfo Pérez Bruzón, Magalys Suárez Quevedo, Richard Hinojosa Aldana, Libán Montes De Oca, Miriam Fariñas Salas & Odalis de la Guardia Peña. (2001) Electrochemical treatment of mouse Ehrlich tumor with direct electric current. Bioelectromagnetics 22:5, pages 316-322.
Crossref
Lanping Ma, Zaiqun Liu, Bo Zhou, Li Yang & Zhongli Liu. (2000) Inhibition of free radical induced oxidative hemolysis of red blood cells by green tea polyphenols. Chinese Science Bulletin 45:22, pages 2052-2056.
Crossref
Jill L. Sondeen, Michael A. Dubick, Yingjie Yu & Adhip P.N. Majumdar. (1999) Hemorrhage and renal ischemia-reperfusion upregulates the epidermal growth factor receptor in rabbit duodenum. Journal of Laboratory and Clinical Medicine 134:6, pages 641-648.
Crossref
Aristo Vojdani, Mamdooh Ghoneum & Paul Choppa. (2016) Minimizing Cancer Risk Using Molecular Techniques: a Review. Toxicology and Industrial Health 13:5, pages 589-626.
Crossref
M. J. Richard, P. Preziosi, J. Arnaud, A. L. Monget, P. Galan, A. Favier & S. Hercberg. 1996. Therapeutic Uses of Trace Elements. Therapeutic Uses of Trace Elements 107 114 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.