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Original Article

Elevated high sensitivity C-reactive protein levels in aging men with low testosterone

, , , &
Pages 108-112 | Received 01 Sep 2009, Accepted 23 Oct 2009, Published online: 10 Dec 2009

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Zelal Jaber Kharaba, Manal Ali Buabeid & Yaseen Abd Alfoteih. (2020) Effectiveness of testosterone therapy in hypogonadal patients and its controversial adverse impact on the cardiovascular system. Critical Reviews in Toxicology 50:6, pages 491-512.
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Nur-Vaizura Mohamad, Sok Kuan Wong, Wan Nuraini Wan Hasan, James Jam Jolly, Mohd Fozi Nur-Farhana, Soelaiman Ima-Nirwana & Kok-Yong Chin. (2019) The relationship between circulating testosterone and inflammatory cytokines in men. The Aging Male 22:2, pages 129-140.
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Kazuyoshi Shigehara, Hiroyuki Konaka, Masashi Ijima, Takahiro Nohara, Kazutaka Narimoto, Koji Izumi, Yoshifumi Kadono, Yasuhide Kitagawa, Atsushi Mizokami & Mikio Namiki. (2016) The correlation between highly sensitive C-reactive protein levels and erectile function among men with late-onset hypogonadism. The Aging Male 19:4, pages 239-243.
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Abraham Morgentaler, Allison Feibus & Neil Baum. (2015) Testosterone and cardiovascular disease – the controversy and the facts. Postgraduate Medicine 127:2, pages 159-165.
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Ali Mohammadrezaei, Abnoos Mokhtari Ardekani, Mahdieh Abbasalizad-Farhangi, Mehran Mesgari-Abbasi & Reihaneh Mousavi. (2023) Association Between Sex Hormone-Binding Globulin, Atherogenic Indices of Plasma Among Young Sedentary Males. Nutrition and Metabolic Insights 16, pages 117863882311550.
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Jacques Baillargeon, Yong‐Fang Kuo, Jordan Westra, David S. Lopez, Randall J. Urban, Stephen B. Williams & Mukaila A. Raji. (2022) Association of testosterone therapy with disease progression in older males with COVID‐19. Andrology 10:6, pages 1057-1066.
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Amar Osmancevic, Kristin Ottarsdottir, Margareta Hellgren, Ulf Lindblad & Bledar Daka. (2022) High C-reactive protein is associated with increased risk of biochemical hypogonadism: a population-based cohort study. Endocrine Connections 11:7.
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Olaya Dios, Leticia Herrero, Claudia Vales‐Villamarín, Ignacio Mahíllo‐Fernández, Leandro Soriano‐Guillén & Carmen Garcés. (2020) Sex steroid hormones, leptin, and high‐sensitivity C‐reactive protein levels in adolescents. Andrology 9:3, pages 829-836.
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Zelal Jaber Kharaba, Manal Ali Buabeid, Nihal A. Ibrahim, Feras Jassim Jirjees, Hala Jehad Al Obaidi, Adnan Kaddaha, Laleh Khajehkarimoddini & Yassen Alfoteih. (2020) Testosterone therapy in hypogonadal patients and the associated risks of cardiovascular events. Biomedicine & Pharmacotherapy 129, pages 110423.
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Thiago Gagliano-Jucá & Shehzad Basaria. (2019) Testosterone replacement therapy and cardiovascular risk. Nature Reviews Cardiology 16:9, pages 555-574.
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Vittorio Emanuele Bianchi. (2019) The Anti-Inflammatory Effects of Testosterone. Journal of the Endocrine Society 3:1, pages 91-107.
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Abdulmaged Traish, Jose Bolanos, Sunil Nair, Farid Saad & Abraham Morgentaler. (2018) Do Androgens Modulate the Pathophysiological Pathways of Inflammation? Appraising the Contemporary Evidence. Journal of Clinical Medicine 7:12, pages 549.
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Thiago Gagliano-Jucá, M Furkan Burak, Karol M Pencina, Zhuoying Li, Robert R Edwards, Thomas G Travison & Shehzad Basaria. (2018) Metabolic Changes in Androgen-Deprived Nondiabetic Men With Prostate Cancer Are Not Mediated by Cytokines or aP2. The Journal of Clinical Endocrinology & Metabolism 103:10, pages 3900-3908.
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Lina Schiffer, Punith Kempegowda, Wiebke Arlt & Michael W O’Reilly. (2017) MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease. European Journal of Endocrinology 177:3, pages R125-R143.
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Jerry Yu, Vanessa A. Ravel, Amy S. You, Elani Streja, Matthew B. Rivara, Praveen K. Potukuchi, Steven M. Brunelli, Csaba P. Kovesdy, Kamyar Kalantar-Zadeh & Connie M. Rhee. (2017) Association between Testosterone and Mortality Risk among U.S. Males Receiving Dialysis. American Journal of Nephrology 46:3, pages 195-203.
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Jacques Baillargeon, Soham Al Snih, Mukaila A. Raji, Randall J. Urban, Gulshan Sharma, Melinda Sheffield-Moore, David S. Lopez, Gwen Baillargeon & Yong-Fang Kuo. (2016) Hypogonadism and the risk of rheumatic autoimmune disease. Clinical Rheumatology 35:12, pages 2983-2987.
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Monique S. Tanna, Arthur Schwartzbard, Jeffery S. Berger, James Underberg, Eugenia Gianos & Howard S. Weintraub. (2016) Management of Hypogonadism in Cardiovascular Patients. Urologic Clinics of North America 43:2, pages 247-260.
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F. Saad, A. Haider & L. Gooren. (2016) Hypogonadal men with psoriasis benefit from long-term testosterone replacement therapy - a series of 15 case reports. Andrologia 48:3, pages 341-346.
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J. Abram McBride, Culley C. CarsonIIIIII & Robert M. Coward. (2015) Testosterone deficiency in the aging male. Therapeutic Advances in Urology 8:1, pages 47-60.
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Kevin Matthew Yen Bing Leung, Khalid Alrabeeah & Serge Carrier. (2015) Update on Testosterone Replacement Therapy in Hypogonadal Men. Current Urology Reports 16:8.
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Mahmoud Nasser, Ahmad Haider, Farid Saad, Winfried Kurtz, Gheorghe Doros, Monika Fijak, Linda Vignozzi & Louis Gooren. (2015) Testosterone therapy in men with Crohn’s disease improves the clinical course of the disease: data from long-term observational registry study. Hormone Molecular Biology and Clinical Investigation 22:3, pages 111-117.
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Monique S. Tanna, Arthur Schwartzbard, Jeffery S. Berger, Joseph Alukal & Howard Weintraub. (2015) The Role of Testosterone Therapy in Cardiovascular Mortality: Culprit or Innocent Bystander?. Current Atherosclerosis Reports 17:3.
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K. K. Tsilidis, S. Rohrmann, K. A. McGlynn, S. J. Nyante, D. S. Lopez, G. Bradwin, M. Feinleib, C. E. Joshu, N. Kanarek, W. G. Nelson, E. Selvin & E. A. Platz. (2013) Association between endogenous sex steroid hormones and inflammatory biomarkers in US men. Andrology 1:6, pages 919-928.
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Joe Butchart, Brian Birch, Ramy Bassily, Laura Wolfe & Clive Holmes. (2013) Male Sex Hormones and Systemic Inflammation in Alzheimer Disease. Alzheimer Disease & Associated Disorders 27:2, pages 153-156.
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Cristina Ferrandis-Cortes, José M. Martínez-Jabaloyas, Nelson A. Díez-Calzadilla, José A. Hernández-Medina & Pascual Chuan-Nuez. (2013) Cardiovascular Risk Assessment Using High-Sensitivity C-Reactive Protein in Patients with Erectile Dysfunction. Urologia Internationalis 91:2, pages 187-191.
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Farid Saad. (2012) Androgen therapy in men with testosterone deficiency: can testosterone reduce the risk of cardiovascular disease?. Diabetes/Metabolism Research and Reviews 28, pages 52-59.
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Pierre Olivier LangDimitrios SamarasNikolaos Samaras. (2012) Testosterone Replacement Therapy in Reversing “Andropause”: What Is the Proof-of-Principle?. Rejuvenation Research 15:5, pages 453-465.
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