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Pharmaceutical Biology Volume 49, 2011 - Issue 4
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Research Article

Cardioprotective effect of whole fruit extract of pomegranate on doxorubicin-induced toxicity in rat

Mohammad Hassanpour FardDepartment of Pharmacology, Birjand University of Medical Sciences, Birjand, Iran and Interdisciplinary School of Health Sciences, University of Pune, Pune, India
,
Arvindkumar E. GhuleDepartment of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth University, Pune, India
,
Subhash L. BodhankarDepartment of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth University, Pune, India
&
Madhurima DikshitBiochemistry Division, Department of Chemistry, University of Pune, Pune, IndiaCorrespondence[email protected]
Pages 377-382 | Received 04 Jun 2009, Accepted 19 Aug 2010, Published online: 11 Mar 2011

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Mohamed A. El-Missiry, Maher A. Amer, Faried A.E. Hemieda, Azza I. Othman, Doaa A. Sakr & Haitham L. Abdulhadi. (2015) Cardioameliorative effect of punicalagin against streptozotocin-induced apoptosis, redox imbalance, metabolic changes and inflammation. Egyptian Journal of Basic and Applied Sciences 2:4, pages 247-260.
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Shankar Prasad Sha, Debabrata Modak, Sourav Sarkar, Sudipta Kumar Roy, Sumit Prasad Sah, Kriti Ghatani & Soumen Bhattacharjee. (2023) Fruit waste: a current perspective for the sustainable production of pharmacological, nutraceutical, and bioactive resources. Frontiers in Microbiology 14.
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Jiejie Cai & Jingye Pan. (2023) Beta vulgaris ‐derived exosome‐like nanovesicles alleviate chronic doxorubicin‐induced cardiotoxicity by inhibiting ferroptosis . Journal of Biochemical and Molecular Toxicology.
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Azar Hosseini, Bibi Marjan Razavi & Hossein Hosseinzadeh. (2023) Protective effects of pomegranate (Punica granatum) and its main components against natural and chemical toxic agents: A comprehensive review. Phytomedicine 109, pages 154581.
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Shraddha I. Khairnar, Yogesh A. Kulkarni & Kavita Singh. (2022) Cardiotoxicity linked to anticancer agents and cardioprotective strategy. Archives of Pharmacal Research 45:10, pages 704-730.
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Xin-Yu Zhang, Ke-Lu Yang, Yang Li, Yang Zhao, Ke-Wei Jiang, Quan Wang & Xiao-Nan Liu. (2022) Can Dietary Nutrients Prevent Cancer Chemotherapy-Induced Cardiotoxicity? An Evidence Mapping of Human Studies and Animal Models. Frontiers in Cardiovascular Medicine 9.
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MuktaS Raj, MangalagowriV Rao & VarnikaRani Singh. (2022) A systematic review on health scenario after COVID19: Conditions and solutions in ayurvedic perspective. Journal of Ayurveda 16:3, pages 228.
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Abdullah F. AlAsmari, Metab Alharbi, Faleh Alqahtani, Fawaz Alasmari, Mohammed AlSwayyed, Sami I. Alzarea, Ibrahim A. Al-Alallah, Adel Alghamdi, Hassan M. Hakami, Meshal K. Alyousef, Youssef Sari & Nemat Ali. (2021) Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study. Antioxidants 10:12, pages 1998.
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Chinyere S. Dike, Chinna N. Orish, Chukwuemeka R. Nwokocha, Francis D. Sikoki, Bolaji B. Babatunde, Chiara Frazzoli & Orish E. Orisakwe. (2021) Phytowaste as nutraceuticals in boosting public health. Clinical Phytoscience 7:1.
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Izabela Koss-Mikołajczyk, Vanja Todorovic, Sladjana Sobajic, Jamal Mahajna, Marko Gerić, Josep A. Tur & Agnieszka Bartoszek. (2021) Natural Products Counteracting Cardiotoxicity during Cancer Chemotherapy: The Special Case of Doxorubicin, a Comprehensive Review. International Journal of Molecular Sciences 22:18, pages 10037.
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Sol-Hui Song, Hye-Jo Min, Min Kyung Kim & Jeong-hee Kim. (2020) Lip Gloss Containing Punica granatum Flower Extract and its Volumizing Effect. Asian Journal of Beauty and Cosmetology 18:2, pages 173-182.
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Sara Kalantari, Leila Roufegarinejad, Sajad Pirsa & Mehdi Gharekhani. (2020) Green extraction of bioactive compounds of pomegranate peel using β-Cyclodextrin and ultrasound. Main Group Chemistry 19:1, pages 61-80.
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Julio César Rodríguez González, René Delgado Hernández & Wim Vanden Berghe. 2020. Natural Products for Cancer Chemoprevention. Natural Products for Cancer Chemoprevention 401 468 .
Sanaz Tavasoli, Shahryar Eghtesadi, Mohamadreza Vafa, Maziar Moradi-Lakeh, Alireza Sadeghipour & Amir-Hassan Zarnani. (2019) High Dose Pomegranate Extract Suppresses Neutrophil Myeloperoxidase and Induces Oxidative Stress in a Rat Model of Sepsis. International Journal for Vitamin and Nutrition Research 89:5-6, pages 271-284.
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Mariana A. Andrade, Vasco Lima, Ana Sanches Silva, Fernanda Vilarinho, Maria Conceição Castilho, Khaoula Khwaldia & Fernando Ramos. (2019) Pomegranate and grape by-products and their active compounds: Are they a valuable source for food applications?. Trends in Food Science & Technology 86, pages 68-84.
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Xinyu Yang, Tianmai He, Songjie Han, Xiaoyu Zhang, Yang Sun, Yanwei Xing & Hongcai Shang. (2019) The Role of Traditional Chinese Medicine in the Regulation of Oxidative Stress in Treating Coronary Heart Disease. Oxidative Medicine and Cellular Longevity 2019, pages 1-13.
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Abdelrahman Ibrahim Abushouk, Ammar Ismail, Amr Muhammad Abdo Salem, Ahmed M. Afifi & Mohamed M. Abdel-Daim. (2017) Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity. Biomedicine & Pharmacotherapy 90, pages 935-946.
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Yin Duan, Xuxu Yan, Lihui Wei, Corinne Bensimon, Pasan Fernando & Terrence D. Ruddy. (2016) Acute and subacute toxicity studies of CMICE-013, a novel iodinated rotenone-based myocardial perfusion tracer, in Sprague Dawley rats and Gottingen minipigs. Regulatory Toxicology and Pharmacology 80, pages 195-209.
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Christian Vlachojannis, Benno F. Zimmermann & Sigrun Chrubasik-Hausmann. (2015) Efficacy and Safety of Pomegranate Medicinal Products for Cancer. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-15.
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J Alvares & M. H. Godinho. (2014) EVALUATION OF NEUROPHARMACOLOGICAL ACTIVITY OF PUNICA GRANATUM L. PEELS IN EXPERIMENTAL RATS. INDIAN DRUGS 51:10, pages 16-22.
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Nadia Z. ShabanMohamed A.R. El-KershMohamed M. Bader-EldinSosan Amin KatoAsmaa F. Hamoda. (2014) Effect of Punica Granatum (Pomegranate) Juice Extract on Healthy Liver and Hepatotoxicity Induced by Diethylnitrosamine and Phenobarbital in Male Rats . Journal of Medicinal Food 17:3, pages 339-349.
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Aishah Al-Jarallah, Fatima Igdoura, Yi Zhang, Christine B. Tenedero, Elizabeth J. White, Melissa E. MacDonald, Suleiman A. Igdoura & Bernardo L. Trigatti. (2013) The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice. Atherosclerosis 228:1, pages 80-89.
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Anupam Bishayee, Roslin J. Thoppil, Altaf S. Darvesh, Vahagn Ohanyan, J. Gary Meszaros & Deepak Bhatia. (2013) Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis. The Journal of Nutritional Biochemistry 24:1, pages 178-187.
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T. K. LimT. K. Lim. 2013. Edible Medicinal And Non-Medicinal Plants. Edible Medicinal And Non-Medicinal Plants 136 194 .
Tariq Ismail, Piero Sestili & Saeed Akhtar. (2012) Pomegranate peel and fruit extracts: A review of potential anti-inflammatory and anti-infective effects. Journal of Ethnopharmacology 143:2, pages 397-405.
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Denys J. CharlesDenys J. Charles. 2013. Antioxidant Properties of Spices, Herbs and Other Sources. Antioxidant Properties of Spices, Herbs and Other Sources 477 487 .

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