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Research Article

Alliin obtained from leaf extract of garlic grown under in situ conditions possess higher therapeutic potency as analyzed in alloxan-induced diabetic rats

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Pages 416-421 | Received 16 May 2010, Accepted 31 Aug 2010, Published online: 11 Mar 2011

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Yayi Jiang, Rensong Yue, Guojie Liu, Jun Liu, Bo Peng, Maoyi Yang, Lianxue Zhao & Zihan Li. (2022) Garlic (Allium sativum L.) in diabetes and its complications: Recent advances in mechanisms of action. Critical Reviews in Food Science and Nutrition 0:0, pages 1-51.
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Min Zhang, Xiaoying Zou, Yixuan Du, Zhuangguang Pan, Fangqing He, Yuanming Sun & Meiying Li. (2023) Integrated Transcriptomics and Metabolomics Reveal the Mechanism of Alliin in Improving Hyperlipidemia. Foods 12:18, pages 3407.
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Shraddha Singh Raghav, Bhavna Kumar, Neeraj Kumar Sethiya & Ankur Kaul. (2022) A Mechanistic Insight on Phytoconstituents Delivering Hypoglycemic Activity: A Comprehensive Overview. Future Pharmacology 2:4, pages 511-546.
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liying he, Fang-Qing Yang, Pan Tang, Ting-Hui Gao, Cai-Xia Yang, Li Tan, Pan Yue, Ya-Nan Hua, Si-Jing Liu & Jin-Lin Guo. (2022) Regulation of the intestinal flora: A potential mechanism of natural medicines in the treatment of type 2 diabetes mellitus. Biomedicine & Pharmacotherapy 151, pages 113091.
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Ijioma Okorie, Chiemela Goodluck N, Amarachi Ihedinachi, Raymond Ade Adesan & Ngozi M. Nnam. (2022) Effect of Mixed Aqueous Extracts of Allium sativum, Annona muricata and Cymbopogon citratus Leaves on the Blood Glucose and Lipid Profile of Hyperglycemic Rats. Asian Journal of Clinical Nutrition 14:1, pages 1-8.
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Aneta Kopeć, Joanna Skoczylas, Elżbieta Jędrszczyk, Renata Francik, Beata Bystrowska & Jerzy Zawistowski. (2020) Chemical Composition and Concentration of Bioactive Compounds in Garlic Cultivated from Air Bulbils. Agriculture 10:2, pages 40.
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Angelo Mark P. Walag, Olatunde Ahmed, Jaison Jeevanandam, Muhammad Akram, Benson Chukwunweike Ephraim-Emmanuel, Chukwuebuka Egbuna, Prabhakar Semwal, Mehwish Iqbal, Sadia Hassan & Joy O. Uba. 2020. Functional Foods and Nutraceuticals. Functional Foods and Nutraceuticals 445 472 .
Solomon Habtemariam. 2019. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases 689 749 .
Baiqiang Zhai, Chuanhai Zhang, Yao Sheng, Changhui Zhao, Xiaoyun He, Wentao Xu, Kunlun Huang & Yunbo Luo. (2018) Hypoglycemic and hypolipidemic effect of S-allyl-cysteine sulfoxide (alliin) in DIO mice. Scientific Reports 8:1.
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Jerzy Zawistowski, Aneta Kopec, Elżbieta Jędrszczyk, Renata Francik & Beata Bystrowska. 2018. Advances in Plant Phenolics: From Chemistry to Human Health. Advances in Plant Phenolics: From Chemistry to Human Health 315 328 .
Arvinda Panthee, Ayana Matsuno, Mohammad Al-Mamun & Hiroaki Sano. (2017) Effect of feeding garlic leaves on rumen fermentation, methane emission, plasma glucose kinetics, and nitrogen utilization in sheep. Journal of Animal Science and Technology 59:1.
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Limin Shi, Qinlu Lin, Xinhua Li, Ying Nie, Shuguo Sun, Xiyun Deng, Long Wang, Jun Lu, Yiping Tang & Feijun Luo. (2017) Alliin, a garlic organosulfur compound, ameliorates gut inflammation through MAPK-NF-κB/AP-1/STAT-1 inactivation and PPAR-γ activation. Molecular Nutrition & Food Research 61:9, pages 1601013.
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Arezou Rezaei, Azad Farzadfard, Atefe Amirahmadi, Maasoomeh Alemi & Mitra Khademi. (2015) Diabetes mellitus and its management with medicinal plants: A perspective based on Iranian research. Journal of Ethnopharmacology 175, pages 567-616.
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SHU-LI WANG, DE-SHAN LIU, ER-SHUN LIANG, YAN-HUA GAO, YING CUI, YU-ZHAO LIU & WEI GAO. (2015) Protective effect of allicin on high glucose/hypoxia-induced aortic endothelial cells via reduction of oxidative stress. Experimental and Therapeutic Medicine 10:4, pages 1394-1400.
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T. K. LimT. K. Lim. 2015. Edible Medicinal and Non Medicinal Plants. Edible Medicinal and Non Medicinal Plants 210 360 .
P.M. Guarrera & V. Savo. (2013) Perceived health properties of wild and cultivated food plants in local and popular traditions of Italy: A review. Journal of Ethnopharmacology 146:3, pages 659-680.
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S.A. Nasim & B. Dhir. 2013. Bioactive Food as Dietary Interventions for Diabetes. Bioactive Food as Dietary Interventions for Diabetes 97 109 .
D. Ortuño Sahagún, A. L. Márquez-Aguirre, S. Quintero-Fabián, R. I. López-Roa & A. E. Rojas-Mayorquín. (2012) Modulation of PPAR- γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases . PPAR Research 2012, pages 1-17.
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