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Pharmaceutical Biology Volume 50, 2012 - Issue 12
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Research Article

Anti-Candida albicans effectiveness of citral and investigation of mode of action

Igara Oliveira LimaPrograma de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos, Centro de Ciências da Saúde (CCS), Universidade Federal da Paraíba (UFPB), João Pessoa, Paraíba, BrasilCorrespondence[email protected]
,
Fernanda de Medeiros NóbregaGraduanda do curso de Farmácia, Departamento de Ciências Farmacêuticas, CCS, UFPB, João Pessoa, Paraíba, Brasil
,
Wylly Araújo de OliveiraCentro de Educação e Saúde, Universidade Federal de Campina Grande, Cuité, Paraíba, Brasil
,
Edeltrudes de Oliveira LimaDepartamento de Ciências Farmacêuticas, CCS, UFPB, João Pessoa, Paraíba, Brasil
,
Everardo Albuquerque MenezesDepartamento de Análises Clínicas, Universidade Federal do Ceará, Fortaleza, Ceará, Brasil
,
Francisco Afrânio CunhaDepartamento de Análises Clínicas, Universidade Federal do Ceará, Fortaleza, Ceará, Brasil
&
Margareth de Fátima Formiga Melo DinizDepartamento de Ciências Farmacêuticas, CCS, UFPB, João Pessoa, Paraíba, Brasil
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Pages 1536-1541 | Received 16 Mar 2011, Accepted 15 May 2012, Published online: 02 Nov 2012

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Katherine Miranda-Cadena, Cristina Marcos-Arias, Aitzol Perez-Rodriguez, Iván Cabello-Beitia, Estibaliz Mateo, Elena Sevillano, Lucila Madariaga, Guillermo Quindós & Elena Eraso. (2022) In vitro and in vivo anti-Candida activity of citral in combination with fluconazole. Journal of Oral Microbiology 14:1.
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Articles from other publishers (21)

Chao-Wei Zhang, Xiao-Jun Zhong, Yun-Shi Zhao, Muhammad Shahid Riaz Rajoka, Muhammad Harris Hashmi, Peng Zhai & Xun Song. (2023) Antifungal natural products and their derivatives: A review of their activity and mechanism of actions. Pharmacological Research - Modern Chinese Medicine 7, pages 100262.
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Anna Biernasiuk & Anna Malm. (2023) Synergistic Interactions between Linalool and Some Antimycotic Agents against Candida spp. as a Basis for Developing New Antifungal Preparations. Applied Sciences 13:9, pages 5686.
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Anna Biernasiuk, Tomasz Baj & Anna Malm. (2022) Clove Essential Oil and Its Main Constituent, Eugenol, as Potential Natural Antifungals against Candida spp. Alone or in Combination with Other Antimycotics Due to Synergistic Interactions. Molecules 28:1, pages 215.
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Zinnat Shahina, Easter Ndlovu, Omkaar Persaud, Taranum Sultana & Tanya E. S. Dahms. (2022) Candida albicans Reactive Oxygen Species (ROS)-Dependent Lethality and ROS-Independent Hyphal and Biofilm Inhibition by Eugenol and Citral . Microbiology Spectrum 10:6.
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Ravi Jothi, Ravichellam Sangavi, Veerapandian Raja, Ponnuchamy Kumar, Shunmugiah Karutha Pandian & Shanmugaraj Gowrishankar. (2022) Alteration of Cell Membrane Permeability by Cetyltrimethylammonium Chloride Induces Cell Death in Clinically Important Candida Species. International Journal of Environmental Research and Public Health 20:1, pages 27.
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Hoang N. H. Tran, Stephanie Udoh, Grace Russell, Oluwadamilola R. Okeyoyin, Sofia Aftab, Isabela Rodriguez, Ebot S. Tabe & Emmanuel C. Adukwu. (2022) Recent Advances in the Application of Essential Oils as Potential Therapeutic Candidates for Candida-Related Infections. Applied Microbiology 2:2, pages 397-413.
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Mohmmad Younus Wani, Aijaz Ahmad, Faisal Mohammed Aqlan & Abdullah Saad Al-Bogami. (2021) Citral derivative activates cell cycle arrest and apoptosis signaling pathways in Candida albicans by generating oxidative stress. Bioorganic Chemistry 115, pages 105260.
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Anna Biernasiuk, Anna Berecka-Rycerz, Anna Gumieniczek, Maria Malm, Krzysztof Z. Łączkowski, Jolanta Szymańska & Anna Malm. (2021) The newly synthesized thiazole derivatives as potential antifungal compounds against Candida albicans. Applied Microbiology and Biotechnology 105:16-17, pages 6355-6367.
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Anna Biernasiuk, Anna Banasiewicz, Maciej Masłyk, Aleksandra Martyna, Monika Janeczko, Angelika Baranowska-Łączkowska, Anna Malm & Krzysztof Z. Łączkowski. (2021) Synthesis and Physicochemical Characterization of Novel Dicyclopropyl-Thiazole Compounds as Nontoxic and Promising Antifungals. Materials 14:13, pages 3500.
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Yong-Jun Cha, Jin Hyeon Kim & Daeung Yu. (2021) Preparation of Macro Fragrance Capsule and Its Stability During Storage. Journal of the Korean Society of Food Science and Nutrition 50:4, pages 420-427.
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Fernando J. Scariot, Mariliza S. Pansera, Ana Paula L. Delamare & Sergio Echeverrigaray. (2021) Citral and geraniol induce necrotic and apoptotic cell death on Saccharomyces cerevisiae. World Journal of Microbiology and Biotechnology 37:3.
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Shanjun Gao, Guangzhi Liu, Jianguo Li, Jing Chen, Lina Li, Zhen Li, Xiulei Zhang, Shoumin Zhang, Rick Francis Thorne & Shuzhen Zhang. (2020) Antimicrobial Activity of Lemongrass Essential Oil (Cymbopogon flexuosus) and Its Active Component Citral Against Dual-Species Biofilms of Staphylococcus aureus and Candida Species. Frontiers in Cellular and Infection Microbiology 10.
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Roopa Gaonkar, Pramod K Avti & Gurumurthy Hegde. (2018) Differential Antifungal Efficiency of Geraniol and Citral. Natural Product Communications 13:12, pages 1934578X1801301.
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Shailee Tiwari, Julio Seijas, Maria Vazquez-Tato, Aniket Sarkate, Kshipra Karnik & Anna Nikalje. (2018) Ionic Liquid-Promoted Synthesis of Novel Chromone-Pyrimidine Coupled Derivatives, Antimicrobial Analysis, Enzyme Assay, Docking Study and Toxicity Study. Molecules 23:2, pages 440.
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Marcela Schenk, Mariana Ferrario & Sandra Guerrero. (2017) Antimicrobial Activity of Binary and Ternary Mixtures of Vanillin, Citral, and Potassium Sorbate in Laboratory Media and Fruit Purées. Food and Bioprocess Technology 11:2, pages 324-333.
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Anna Pratima G. Nikalje, Shailee V. Tiwari, Aniket P. Sarkate & Kshipra S. Karnik. (2017) Imidazole-thiazole coupled derivatives as novel lanosterol 14-α demethylase inhibitors: ionic liquid mediated synthesis, biological evaluation and molecular docking study. Medicinal Chemistry Research 27:2, pages 592-606.
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Shailee Tiwari, Julio Seijas, Maria Vazquez-Tato, Aniket Sarkate, Kshipra Karnik & Anna Nikalje. (2017) Facile Synthesis of Novel Coumarin Derivatives, Antimicrobial Analysis, Enzyme Assay, Docking Study, ADMET Prediction and Toxicity Study. Molecules 22:7, pages 1172.
Crossref
Julliana Cariry Palhano Freire, José Klidenberg de Oliveira Júnior, Daniele de Figueredo Silva, Janiere Pereira de Sousa, Felipe Queiroga Sarmento Guerra & Edeltrudes de Oliveira Lima. (2017) Antifungal Activity of Essential Oils against Candida albicans Strains Isolated from Users of Dental Prostheses . Evidence-Based Complementary and Alternative Medicine 2017, pages 1-9.
Crossref
Maria Clerya Alvino Leite, André Parente de Brito Bezerra, Janiere Pereira de Sousa & Edeltrudes de Oliveira Lima. (2015) Investigating the antifungal activity and mechanism(s) of geraniol against Candida albicans strains. Medical Mycology 53:3, pages 275-284.
Crossref
Naouel Chaftar, Marion Girardot, Jérôme Labanowski, Tawfik Ghrairi, Khaled Hani, Jacques Frère & Christine Imbert. 2016. Advances in Microbiology, Infectious Diseases and Public Health. Advances in Microbiology, Infectious Diseases and Public Health 1 15 .
Maria Clerya Alvino Leite, André Parente de Brito Bezerra, Janiere Pereira de Sousa, Felipe Queiroga Sarmento Guerra & Edeltrudes de Oliveira Lima. (2014) Evaluation of Antifungal Activity and Mechanism of Action of Citral against Candida albicans . Evidence-Based Complementary and Alternative Medicine 2014, pages 1-9.
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