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Research Article

Syringic acid from Tamarix aucheriana possesses antimitogenic and chemo-sensitizing activities in human colorectal cancer cells

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Pages 1110-1124 | Received 20 Feb 2012, Accepted 27 Feb 2013, Published online: 07 Jun 2013

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Azar Zochedh, Mohana Priya, Cibe Chakaravarthy, Asath Bahadur Sultan & Thandavarayan Kathiresan. (2023) Experimental and Computational Evaluation of Syringic Acid – Structural, Spectroscopic, Biological Activity and Docking Simulation. Polycyclic Aromatic Compounds 43:7, pages 6516-6548.
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Periyannan Velu, Veerasamy Vinothkumar, Sukumar Babukumar & Duraisamy Ramachandhiran. (2017) Chemopreventive effect of syringic acid on 7,12-dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis. Toxicology Mechanisms and Methods 27:8, pages 631-640.
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Lina Yang, Changhong Qu, Jiaxi Jin, Hong Yang & Lipeng Pei. (2021) Syringic acid regulates suppression of the STAT3/JNK/AKT pathway via inhibition of human ovarian teratoma cancer cell (PA‐1) growth—in vitro study. Journal of Biochemical and Molecular Toxicology 35:6, pages 1-9.
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. (2020) Retracted : Syringic acid suppresses oral squamous cell carcinoma SCC131 cell proliferation via modulation of mitochondria‐mediated apoptosis signaling pathways . Journal of Biochemical and Molecular Toxicology 34:12.
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. (2020) Retracted : Syringic acid modulates molecular marker–involved cell proliferation, survival, apoptosis, inflammation, and angiogenesis in DMBA‐induced oral squamous cell carcinoma in Syrian hamsters . Journal of Biochemical and Molecular Toxicology 34:11.
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Periyannan Velu, Annamalai Vijayalakshmi & Veerasamy Vinothkumar. (2020) Retracted: Inhibiting the PI3K/Akt, NF-κB signalling pathways with syringic acid for attenuating the development of oral squamous cell carcinoma cells SCC131. Journal of Pharmacy and Pharmacology 72:11, pages 1595-1606.
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Bhaskhar Abijeth & Devaraj Ezhilarasan. (2020) Syringic acid induces apoptosis in human oral squamous carcinoma cells through mitochondrial pathway. Journal of Oral and Maxillofacial Pathology 24:1, pages 40.
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Roodabeh Bahramsoltani, Mahdieh Kalkhorani, Syed Mohd Abbas Zaidi, Mohammad Hosein Farzaei & Roja Rahimi. (2020) The genus Tamarix: Traditional uses, phytochemistry, and pharmacology. Journal of Ethnopharmacology 246, pages 112245.
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Rasha M. Allam, Ali M. El-Halawany & Ahmed M. Al-Abd. 2020. Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies. Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies 93 116 .
Ha Na Kim, Gwang Hun Park, Su Bin Park, Jeong Dong Kim, Hyun Ji Eo, Ho-Jun Son, Jeong Ho Song & Jin Boo Jeong. (2019) Extracts from Sageretia thea reduce cell viability through inducing cyclin D1 proteasomal degradation and HO-1 expression in human colorectal cancer cells. BMC Complementary and Alternative Medicine 19:1.
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Maged Mohamed Maher Abou-Hashem, Dina Mohamed Abo-elmatty, Noha Mostafa Mesbah & Ahmed Mohamed Abd EL-Mawgoud. (2019) Induction of sub-G0 arrest and apoptosis by seed extract of Moringa peregrina (Forssk.) Fiori in cervical and prostate cancer cell lines. Journal of Integrative Medicine 17:6, pages 410-422.
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Teruyoshi Tanaka, Hiroki Onuma, Takashi Shigihara, Eiichi Kimura, Yasuhisa Fukuta, Norifumi Shirasaka, Tatsuya Moriyama & Yoshimi Homma. (2019) Anti-osteoporotic effects of syringic acid and vanilic acid in the extracts of waste beds after mushroom cultivation. Journal of Bioscience and Bioengineering 128:5, pages 622-629.
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S Gheena & D Ezhilarasan. (2019) Syringic acid triggers reactive oxygen species–mediated cytotoxicity in HepG2 cells. Human & Experimental Toxicology 38:6, pages 694-702.
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Aleksandra Golonko, Tomasz Pienkowski, Renata Swislocka, Ryszard Lazny, Marek Roszko & Wlodzimierz Lewandowski. (2019) Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system. European Journal of Medicinal Chemistry 167, pages 291-311.
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Yinfang Li, Li Zhang, Xiaohua Wang, wei wu & Rui Qin. (2018) Effect of Syringic acid on antioxidant biomarkers and associated inflammatory markers in mice model of asthma. Drug Development Research 80:2, pages 253-261.
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Tomasz Kowalczyk, Przemysław Sitarek, Ewa Skała, Monika Toma, Marzena Wielanek, Dariusz Pytel, Joanna Wieczfińska, Janusz Szemraj & Tomasz Śliwiński. (2019) Induction of apoptosis by in vitro and in vivo plant extracts derived from Menyanthes trifoliata L. in human cancer cells. Cytotechnology 71:1, pages 165-180.
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Cheemanapalli Srinivasulu, Mopuri Ramgopal, Golla Ramanjaneyulu, C.M. Anuradha & Chitta Suresh Kumar. (2018) Syringic acid (SA) ‒ A Review of Its Occurrence, Biosynthesis, Pharmacological and Industrial Importance. Biomedicine & Pharmacotherapy 108, pages 547-557.
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Srinivasulu Cheemanapalli, Anuradha C.M.Suresh Babu Pakala & Suresh Kumar Chitta. (2018) Design and screening of syringic acid analogues as BAX activators-An in silico approach to discover “BH3 mimetics”. Computational Biology and Chemistry 74, pages 49-62.
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Arun K. B., Aravind Madhavan, Reshmitha T. R.Sithara ThomasP. Nisha. (2018) Musa paradisiaca inflorescence induces human colon cancer cell death by modulating cascades of transcriptional events . Food & Function 9:1, pages 511-524.
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Shou-Kun Ding, Li-Xia Wang, Lei-Sheng Guo, Ping Luo, Juan-Juan Du, Zong-Lei Zhao & Guang-Gong Wang. (2017) Syringic acid inhibits apoptosis pathways via downregulation of p38MAPK and JNK signaling pathways in H9c2 cardiomyocytes following hypoxia/reoxygenation injury. Molecular Medicine Reports 16:2, pages 2290-2294.
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Ju Ri Ham, Hae-In Lee, Ra-Yeong Choi, Mi-Ok Sim, Kwon-Il Seo & Mi-Kyung Lee. (2016) Anti-steatotic and anti-inflammatory roles of syringic acid in high-fat diet-induced obese mice. Food & Function 7:2, pages 689-697.
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Gowri Karthik, Mangalagowri Angappan, Arunkumar VijayaKumar & Sukumaran Natarajapillai. (2014) Syringic acid exerts antiangiogenic activity by downregulation of VEGF in zebrafish embryos. Biomedicine & Preventive Nutrition 4:2, pages 203-208.
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