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Research Article

Pharmacokinetic analysis and tissue distribution of andrographolide in rat by a validated LC-MS/MS method

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Pages 321-329 | Received 11 May 2013, Accepted 15 Aug 2013, Published online: 30 Oct 2013

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Sok Kuan Wong, Kok-Yong Chin & Soelaiman Ima-Nirwana. (2021) A review on the molecular basis underlying the protective effects of Andrographis paniculata and andrographolide against myocardial injury. Drug Design, Development and Therapy 15, pages 4615-4632.
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Jing-Jing Zhang, Ting-Ting Gao, Yuan Wang, Jin-Liang Wang, Wei Guan, Ying-Jie Wang, Cheng-Niu Wang, Jian-Feng Liu & Bo Jiang. (2019) Andrographolide Exerts Significant Antidepressant-Like Effects Involving the Hippocampal BDNF System in Mice. International Journal of Neuropsychopharmacology 22:9, pages 585-600.
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Sunil Kumar, Awantika Singh, Vikas Bajpai, Kulwant R. Sharma & Brijesh Kumar. (2018) Identification and Characterization of Terpenoid Lactones and Flavonoids from Ethanolic Extract of Andrographis Paniculata (Burm.f.) Nees Using Liquid Chromatography/Tandem Mass Spectrometry . SEPARATION SCIENCE PLUS 1:12, pages 762-770.
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Xiang Li, Tianyi Wang, Dongping Zhang, Haiying Li, Haitao Shen, Xin Ding & Gang Chen. (2018) Andrographolide ameliorates intracerebral hemorrhage induced secondary brain injury by inhibiting neuroinflammation induction. Neuropharmacology 141, pages 305-315.
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Fei Gao, Xing Liu, Ziying Shen, Xiaohui Jia, Han He, Jing Gao, Jianhong Wu, Chunhong Jiang, Hu Zhou & Yiping Wang. (2018) Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice. Frontiers in Physiology 9.
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Malabika Banerjee, Subrata Chattopadhyay, Tathagata Choudhuri, Rammohan Bera, Sanjay Kumar, Biswajit Chakraborty & Samir Kumar Mukherjee. (2016) Cytotoxicity and cell cycle arrest induced by andrographolide lead to programmed cell death of MDA-MB-231 breast cancer cell line. Journal of Biomedical Science 23:1.
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Yu Zhang, Xi Hu, Xiaolin Liu, Yu Dandan, Donghua Di, Tian Yin, Shu Zhang & Xing Tang. (2015) Dry state microcrystals stabilized by an HPMC film to improve the bioavailability of andrographolide. International Journal of Pharmaceutics 493:1-2, pages 214-223.
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Preeti Chandra, Renu Pandey, Mukesh Srivastva & Brijesh Kumar. (2015) Quality control assessment of polyherbal formulation based on a quantitative determination multimarker approach by ultra high performance liquid chromatography with tandem mass spectrometry using polarity switching combined with multivariate analysis. Journal of Separation Science 38:18, pages 3183-3191.
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Fang-fang Xu, Shu-jun Fu, Sheng-pan Gu, Zhi-min Wang, Zhen-zhong Wang, Xin He & Wei Xiao. (2015) Simultaneous determination of andrographolide, dehydroandrographolide and neoandrographolide in dog plasma by LC–MS/MS and its application to a dog pharmacokinetic study of Andrographis paniculata tablet. Journal of Chromatography B 990, pages 125-131.
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Siew-Ying Wong, Su-Jing Chan, W.S. Fred Wong, Peter T.-H. Wong & Mitchell K.P. Lai. (2014) Andrographolide attenuates interleukin-1β-stimulated upregulation of chemokine CCL5 and glial fibrillary acidic protein in astrocytes. NeuroReport 25:12, pages 881-886.
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