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Pharmaceutical Biology Volume 54, 2016 - Issue 9
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Research Article

HPLC-DAD phenolic profile, cytotoxic and anti-kinetoplastidae activity of Melissa officinalis

Francisco CunhaDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil; ;Programa De Pós-Graduação Em Bioquímica Toxicológica, Universidade Federal De Santa Maria – UFSM, Santa Maria, RS, Brazil;
,
Saulo R. TintinoDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil;
,
Fernando FigueredoDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil;
,
Luiz BarrosDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil; ;Programa De Pós-Graduação Em Bioquímica Toxicológica, Universidade Federal De Santa Maria – UFSM, Santa Maria, RS, Brazil;
,
Antonia E. DuarteDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil; ;Programa De Pós-Graduação Em Bioquímica Toxicológica, Universidade Federal De Santa Maria – UFSM, Santa Maria, RS, Brazil;
,
Maria Celeste Vega GomezCentro Para El Desarrollo De La Investigación Científica (CEDIC), Fundación Moisés Bertoni/Laboratorios Díaz Gill, Asunción, Paraguay;
,
Cathia Cecilia CoronelCentro Para El Desarrollo De La Investigación Científica (CEDIC), Fundación Moisés Bertoni/Laboratorios Díaz Gill, Asunción, Paraguay;
,
Mírian RolónCentro Para El Desarrollo De La Investigación Científica (CEDIC), Fundación Moisés Bertoni/Laboratorios Díaz Gill, Asunción, Paraguay;
,
Nadghia LeiteDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil;
,
Celestina E. Sobral-SouzaDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil;
,
S. V. BritoDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil;
,
Emily Pansera WaczucDepartamento de Bioquimica e Biologia Molecular, Bioquímica Toxicológica, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul 97105-900, Brazil;
,
Aline Augusti BoligonUniversidade Federal Dos Pampas, São Gabriel, RS, Brazil;
,
Margareth AthaydeUniversidade Federal Dos Pampas, São Gabriel, RS, Brazil;
,
Jean Paul KamdemDepartamento de Bioquimica e Biologia Molecular, Bioquímica Toxicológica, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul 97105-900, Brazil; ;Departamento de Bioquímica, Instituto de Ciências Básica da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS CEP 90035-003, Brazil
,
Henrique Douglas Melo CoutinhoDepartamento De Química Biológica, Laboratório De Microbiologia E Biologia Molecular, Universidade Regional Do Cariri, Crato, CE, Brazil; Correspondence[email protected]
&
Jéferson FrancoPrograma De Pós-Graduação Em Bioquímica Toxicológica, Universidade Federal De Santa Maria – UFSM, Santa Maria, RS, Brazil; ;Universidade Federal Dos Pampas, São Gabriel, RS, Brazil;
show all
Pages 1664-1670 | Received 09 Mar 2015, Accepted 11 Nov 2015, Published online: 10 Feb 2016

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Andreza R. Garcia, Danielle M. P. Oliveira, Ana Claudia F. Amaral, Jéssica B. Jesus, Ana Carolina Rennó Sodero, Alessandra M. T. Souza, Claudiu T. Supuran, Alane B. Vermelho, Igor A. Rodrigues & Anderson S. Pinheiro. (2019) Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1100-1109.
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Articles from other publishers (9)

Da-Hye Ryu, Jwa-Yeong Cho, Seung-Hoon Yang & Ho-Youn Kim. (2023) Effects of Harvest Timing on Phytochemical Composition in Lamiaceae Plants under an Environment-Controlled System. Antioxidants 12:11, pages 1909.
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Roberto Castro-Muñoz, Grzegorz Boczkaj & René Cabezas. (2023) A Perspective on Missing Aspects in Ongoing Purification Research towards Melissa officinalis. Foods 12:9, pages 1916.
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Pascaline Aimee Uwineza, Monika Urbaniak, Marcin Bryła, Łukasz Stepien, Marta Modrzewska & Agnieszka Waśkiewicz. (2022) In Vitro Effects of Lemon Balm Extracts in Reducing the Growth and Mycotoxins Biosynthesis of Fusarium culmorum and F. proliferatum. Toxins 14:5, pages 355.
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Gabriela Petrisor, Ludmila Motelica, Luminita Narcisa Craciun, Ovidiu Cristian Oprea, Denisa Ficai & Anton Ficai. (2022) Melissa officinalis: Composition, Pharmacological Effects and Derived Release Systems—A Review. International Journal of Molecular Sciences 23:7, pages 3591.
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Rafael Marlon Alves de Assis, Joana Junqueira Carneiro, Ana Paula Ribeiro Medeiros, Alexandre Alves de Carvalho, Alan da Cunha Honorato, Marco Aurélio Carbone Carneiro, Suzan Kelly Vilela Bertolucci & José Eduardo Brasil Pereira Pinto. (2020) Arbuscular mycorrhizal fungi and organic manure enhance growth and accumulation of citral, total phenols, and flavonoids in Melissa officinalis L. Industrial Crops and Products 158, pages 112981.
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J.W.A. Bezerra, C. Coronel, M.C.V. Gomez, M. Rolón, C.V. Nunez, D.R. da Silva, L.A. da Silva, F.C. Rodrigues, A.A. Boligon, M.A. de Souza, K.V. Linhares, M.A.P. da Silva & M.F.B. Morais-Braga. (2019) Evaluation of antiparasitary, cytotoxic and antioxidant activity and chemical analysis of Tarenaya spinosa (Jacq.) Raf. (Cleomaceae). South African Journal of Botany 124, pages 546-555.
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Arantzazu Santamaria-Echart, Isabel Fernandes, Filomena Barreiro, Aloña Retegi, Aitor Arbelaiz, Maria Angeles Corcuera & Arantxa Eceiza. (2018) Development of waterborne polyurethane-ureas added with plant extracts: Study of different incorporation routes and their influence on particle size, thermal, mechanical and antibacterial properties. Progress in Organic Coatings 117, pages 76-90.
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Maxime M. Boneza & Emily D. Niemeyer. (2018) Cultivar affects the phenolic composition and antioxidant properties of commercially available lemon balm ( Melissa officinalis L.) varieties. Industrial Crops and Products 112, pages 783-789.
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Remigius Chizzola, Ulrike Lohwasser & Chlodwig Franz. (2018) Biodiversity within Melissa officinalis: Variability of Bioactive Compounds in a Cultivated Collection. Molecules 23:2, pages 294.
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