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Pharmaceutical Biology Volume 54, 2016 - Issue 9
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Review Article

Histone deacetylase inhibitor pracinostat in doublet therapy: a unique strategy to improve therapeutic efficacy and to tackle herculean cancer chemoresistance

Shabir Ahmad GanaiPlant Virology and Molecular Pathology Laboratory, Division of Plant Pathology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shalimar, Srinagar, Jammu & Kashmir, IndiaCorrespondence[email protected]
Pages 1926-1935 | Received 06 Sep 2015, Accepted 17 Dec 2015, Published online: 05 Feb 2016

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Ahsan Anjoom Sunil & Tom Skaria. (2022) Novel regulators of airway epithelial barrier function during inflammation: potential targets for drug repurposing. Expert Opinion on Therapeutic Targets 26:2, pages 119-132.
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Xiao-Ling Liang, Lan Ouyang, Nan-Nan Yu, Zheng-Hua Sun, Zi-Kang Gui, Yu-Long Niu, Qing-Yu He, Jing Zhang & Yang Wang. (2023) Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission. Journal of Pharmaceutical Analysis 13:10, pages 1168-1182.
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Yuxin Wei, Yuyan Guo & Shaowa Lv. (2022) Research on the progress of Traditional Chinese medicine components and preparations on histone deacetylase inhibitors - Like effects in the course of disease treatment. Journal of Ethnopharmacology 296, pages 115521.
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Parin Salim Sidat, Tasneem Mohamadbin Kasim Jaber, Shwetang Ramesh Vekariya, Azmin Mahervan Mogal, Aarifa Mustak Patel & Malleshappa Noolvi. (2022) Anticancer Biological Profile of Some Heterocylic Moieties-Thiadiazole, Benzimidazole, Quinazoline, and Pyrimidine. Pharmacophore 13:4, pages 59-71.
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Xiuhong Wei, Bolian Xiao, Liying Wang, Lanlan Zang & Fengyuan Che. (2021) Potential new targets and drugs related to histone modifications in glioma treatment. Bioorganic Chemistry 112, pages 104942.
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Shabir Ahmad Ganai. (2021) Characterizing binding intensity and energetic features of histone deacetylase inhibitor pracinostat towards class I HDAC isozymes through futuristic drug designing strategy. In Silico Pharmacology 9:1.
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Sachan Richa, Prasanta Dey, Chaeun Park, Jungho Yang, Ji Yeon Son, Jae Hyeon Park, Su Hyun Lee, Mee-Young Ahn, In Su Kim, Hyung Ryong Moon & Hyung Sik Kim. (2020) A New Histone Deacetylase Inhibitor, MHY4381, Induces Apoptosis via Generation of Reactive Oxygen Species in Human Prostate Cancer Cells. Biomolecules & Therapeutics 28:2, pages 184-194.
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Shabir Ahmad GanaiShabir Ahmad Ganai. 2020. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy 173 201 .
Shabir Ahmad GanaiShabir Ahmad Ganai. 2020. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy. Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy 67 74 .
Chengwu Han, Xueying Yu, Chunxia Zhang, Ying Cai, Yongyue Cao, Sijie Wang & Jun Shen. (2019) Drug Repurposing Screen Identifies Novel Classes of Drugs with Anticancer Activity in Mantle Cell Lymphoma. Combinatorial Chemistry & High Throughput Screening 22:7, pages 483-495.
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Yu Bai, Daid Ahmad, Ting Wang, Guihua Cui & Wenliang Li. (2019) Research Advances in the Use of Histone Deacetylase Inhibitors for Epigenetic Targeting of Cancer. Current Topics in Medicinal Chemistry 19:12, pages 995-1004.
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Rong Jia, Pengju Sun, Yan Zhang, Youjin Ge & Niefang Yu. (2019) Minor structural modifications to Pracinostat produce big changes in its biological responses. Chemical Biology & Drug Design.
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Ravikumar Vilwanathan, Anusha Chidambaram & Ramesh Kumar Chidambaram. 2019. Pharmacoepigenetics. Pharmacoepigenetics 437 445 .
Shabir Ahmad GanaiShabir Ahmad Ganai. 2019. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders 11 19 .
Shabir Ahmad GanaiShabir Ahmad Ganai. 2019. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders 1 10 .
Amarjeet Kumar, Suman Kumar Dhar & Naidu Subbarao. (2018) In silico identification of inhibitors against Plasmodium falciparum histone deacetylase 1 (PfHDAC-1). Journal of Molecular Modeling 24:9.
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Shabir Ahmad Ganai, Ehsaan Abdullah, Romana Rashid & Mohammad Altaf. (2017) Combinatorial In Silico Strategy towards Identifying Potential Hotspots during Inhibition of Structurally Identical HDAC1 and HDAC2 Enzymes for Effective Chemotherapy against Neurological Disorders. Frontiers in Molecular Neuroscience 10.
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