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Pharmaceutical Biology Volume 54, 2016 - Issue 11
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Research Article

Brown seaweeds protect against azoxymethane-induced hepatic repercussions through up-regulation of peroxisome proliferator-activated receptor gamma and attenuation of oxidative stress

Ehab M. AbdellaCell Biology and Genetics Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt;
,
Ayman M. MahmoudPhysiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt
&
Azza M. El-DerbyCell Biology and Genetics Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt; Correspondence[email protected]
Pages 2496-2504 | Received 13 Mar 2015, Accepted 28 Feb 2016, Published online: 06 Apr 2016

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André Luís Nunes Avelino, Nina Victória Ribeiro e Silva, Gilson Brito De Oliveira, Antônio Adailson De Sousa Silva, Bruno Coêlho Cavalcanti, Francisco Vagnaldo Fechine Jamacaru & Conceição Aparecida Dornelas. (2022) Antioxidant and Antigenotoxic Actions of Gum Arabic on the Intestinal Mucosa, Liver and Bone Marrow of Swiss Mice Submitted to Colorectal Carcinogenesis. Nutrition and Cancer 74:3, pages 956-964.
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Aya E. Mohamed, Ayman M. Mahmoud, Wafaa R. Mohamed & Tarek Mohamed. (2022) Femtosecond laser attenuates oxidative stress, inflammation, and liver fibrosis in rats: Possible role of PPARγ and Nrf2/HO-1 signaling. Life Sciences 307, pages 120877.
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Maria AZAM, Khan HIRA, Shamim A. QURESHI, Nasira KHATOON, Jehan ARA & Syed EHTESHAMUL-HAQUE. (2022) Ameliorative Effect of Marine Macroalgae on Carbon Tetrachloride-Induced Hepatic Fibrosis and Associated Complications in Rats. Turkish Journal of Pharmaceutical Sciences 19:2, pages 116-124.
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Rahima Begum, Saurav Howlader, A. N. M. Mamun-Or-Rashid, S. M. Rafiquzzaman, Ghulam Md Ashraf, Ghadeer M. Albadrani, Amany A. Sayed, Ilaria Peluso, Mohamed M. Abdel-Daim & Md. Sahab Uddin. (2021) Antioxidant and Signal-Modulating Effects of Brown Seaweed-Derived Compounds against Oxidative Stress-Associated Pathology. Oxidative Medicine and Cellular Longevity 2021, pages 1-22.
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Chenhan Zhong, Li He, Sun-Young Lee, Hang Chang, Yuqing Zhang, David W. Threadgill, Ying Yuan, Fuling Zhou, Susan E. Celniker, Yankai Xia, Antoine M. Snijders & Jian-Hua Mao. (2021) Host genetics and gut microbiota cooperatively contribute to azoxymethane-induced acute toxicity in Collaborative Cross mice. Archives of Toxicology 95:3, pages 949-958.
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Ayman M. Mahmoud, May Bin-Jumah & Mohammad H. Abukhalil. 2021. Inflammation and Natural Products. Inflammation and Natural Products 131 159 .
Seon Min Lee, Na-Hyun Kim, Yeong Kwang Ji, Yun Na Kim, You-Jin Jeon, Jeong Doo Heo, Eun Ju Jeong & Jung-Rae Rho. (2020) Sulfoquinovosylmonoacylglycerols regulating intestinal inflammation in co-culture system from the brown alga <italic>Turbinaria ornata</italic>. ALGAE 35:2, pages 201-212.
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Nam Su Oh, Jae Yeon Joung, Ji Young Lee, Youn Jeong Kim, Younghoon Kim & Sae Hun Kim. (2020) A synbiotic combination of Lactobacillus gasseri 505 and Cudrania tricuspidata leaf extract prevents hepatic toxicity induced by colorectal cancer in mice. Journal of Dairy Science 103:4, pages 2947-2955.
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Hualin Liu, Lei Zhang, Guanghua Li & Zhuanglei Gao. (2019) Xanthohumol protects against Azoxymethane‐induced colorectal cancer in Sprague‐Dawley rats. Environmental Toxicology 35:2, pages 136-144.
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Mousa O. Germoush, Hassan A. Elgebaly, Sherif Hassan, Emadeldin M. Kamel, May Bin-Jumah & Ayman M. Mahmoud. (2019) Consumption of Terpenoids-Rich Padina pavonia Extract Attenuates Hyperglycemia, Insulin Resistance and Oxidative Stress, and Upregulates PPARγ in a Rat Model of Type 2 Diabetes. Antioxidants 9:1, pages 22.
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Aarón Kuri-GarcíaRosa Iris Godínez-SantillánCarmen MejíaRoberto Augusto Ferriz-MartínezPablo García-SolísAlejandro Enríquez-VázquezTeresa García-GascaSalvador Horacio Guzmán-MaldonadoJorge Luis Chávez-Servín. (2019) Preventive Effect of an Infusion of the Aqueous Extract of Chaya Leaves ( Cnidoscolus aconitifolius ) in an Aberrant Crypt Foci Rat Model Induced by Azoxymethane and Dextran Sulfate Sodium . Journal of Medicinal Food 22:8, pages 851-860.
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Ayman M. Mahmoud, Walaa G. Hozayen, Iman H. Hasan, Eman Shaban & May Bin-Jumah. (2019) Umbelliferone Ameliorates CCl4-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling. Inflammation 42:3, pages 1103-1116.
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Ayman M. Mahmoud, Hanaa M. Mohammed, Sally M. Khadrawy & Sanaa R. Galaly. (2017) Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation. Chemico-Biological Interactions 277, pages 146-158.
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Ayman M. Mahmoud, Walaa G. Hozayen & Shimaa M. Ramadan. (2017) Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats. Biomedicine & Pharmacotherapy 94, pages 280-291.
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Ayman M. Mahmoud, Omnia E. Hussein, Walaa G. Hozayen & Sanaa M. Abd El-Twab. (2017) Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-Glycyrrhetinic acid. Chemico-Biological Interactions 270, pages 59-72.
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Sultan Alqahtani & Ayman M. Mahmoud. (2016) Gamma-Glutamylcysteine Ethyl Ester Protects against Cyclophosphamide-Induced Liver Injury and Hematologic Alterations via Upregulation of PPAR γ and Attenuation of Oxidative Stress, Inflammation, and Apoptosis . Oxidative Medicine and Cellular Longevity 2016, pages 1-14.
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