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Original Article

Effects of methylprednisolone on complement activation and leukocyte counts during cardiopulmonary bypass

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Pages 255-261 | Accepted 22 Dec 1986, Published online: 12 Jul 2009

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K. Mikawa, J. Ikegaki, N. Maekawa, H. Hoshina, O. Tanaka, R. Goto, H. Obara & M. Kusunoki. (1990) Perioperative Effect of Methylprednisolone Given During Lung Surgery on Plasma Concentrations of C3a and C5a. Scandinavian Journal of Thoracic and Cardiovascular Surgery 24:3, pages 229-233.
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Articles from other publishers (28)

Alemayehu H. Jufar, Yugeesh R. Lankadeva, Clive N. May, Andrew D. Cochrane, Bruno Marino, Rinaldo Bellomo & Roger G. Evans. 2011. Comprehensive Physiology. Comprehensive Physiology 2799 2834 .
Richard Hall. (2013) Identification of Inflammatory Mediators and Their Modulation by Strategies for the Management of the Systemic Inflammatory Response During Cardiac Surgery. Journal of Cardiothoracic and Vascular Anesthesia 27:5, pages 983-1033.
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Jan M Dieleman, Judith van Paassen, Diederik van Dijk, M. Sesmu Arbous, Cor J Kalkman, Jan P Vandenbroucke, Geert J van der Heijden & Olaf M Dekkers. (2011) Prophylactic corticosteroids for cardiopulmonary bypass in adults. Cochrane Database of Systematic Reviews.
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Giangiuseppe Cappabianca, Crescenzia Rotunno, Luigi de Luca Tupputi Schinosa, V. Marco Ranieri & Domenico Paparella. (2011) Protective Effects of Steroids in Cardiac Surgery: A Meta-Analysis of Randomized Double-Blind Trials. Journal of Cardiothoracic and Vascular Anesthesia 25:1, pages 156-165.
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Jan M Dieleman, Judith van Paassen, Diederik van Dijk, Sesmu M Arbous, Cor J Kalkman, Jan P Vandenbroucke, Geert J van der Heijden & Olaf M Dekkers. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Stefan JM Dieleman & J van Klarenbosch. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Albert J. Chong, Craig R. Hampton & Edward D. Verrier. (2016) Microvascular Inflammatory Response in Cardiac Surgery. Seminars in Cardiothoracic and Vascular Anesthesia 7:3, pages 333-354.
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Kathrine Holte & Henrik Kehlet. (2002) Perioperative Single-Dose Glucocorticoid Administration: Pathophysiologic Effects and Clinical Implications. Journal of the American College of Surgeons 195:5, pages 694-712.
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Mark A. Chaney. (2002) Corticosteroids and Cardiopulmonary Bypass. Chest 121:3, pages 921-931.
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Oliver M. Frass, Frank Bu¨hling, Michael Ta¨ger, Heidrun Frass, Siegfried Ansorge, Christof Huth & Tobias Welte. (2001) Antioxidant and Antiprotease Status in Peripheral Blood and BAL Fluid After Cardiopulmonary Bypass. Chest 120:5, pages 1599-1608.
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İlker AlatMünevver Yüksel, Suat Büket, Sanem Nalbantgil, Fatma Aşkar, Ülkü Bayındır, Sezai Taşbakan, Ali Kokuludag & Ali Veral. (2016) The side-effects of cardiopulmonary bypass on the lungs: changes in bronchoalveolar lavage fluids. Perfusion 16:2, pages 121-128.
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Mark A. Chaney, Ramòn A. Durazo-Arvizu, Mihail P. Nikolov, Bradford P. Blakeman & Mamdouh Bakhos. (2001) Methylprednisolone does not benefit patients undergoing coronary artery bypass grafting and early tracheal extubation. The Journal of Thoracic and Cardiovascular Surgery 121:3, pages 561-569.
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Stefan Sauerland, Manfred Nagelschmidt, Peter Mallmann & Edmund A.M. Neugebauer. (2000) Risks and Benefits of Preoperative High Dose Methylprednisolone in Surgical Patients. Drug Safety 23:5, pages 449-461.
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Mark A. Chaney, Mihail P. Nikolov, Bradford P. Blakeman, Mamdouh Bakhos & Stephen Slogoff. (1999) Hemodynamic effects of methylprednisolone in patients undergoing cardiac operation and early extubation. The Annals of Thoracic Surgery 67:4, pages 1006-1011.
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Mark A. Chaney, Mihail P. Nikolov, Bradford Blakeman, Mamdouh Bakhos & Stephen Slogoff. (1998) Pulmonary Effects of Methylprednisolone in Patients Undergoing Coronary Artery Bypass Grafting and Early Tracheal Extubation. Anesthesia & Analgesia 87:1, pages 27-33.
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Richard I. Hall, Mark Stafford Smith & Graeme Rocker. (1997) The Systemic Inflammatory Response to Cardiopulmonary Bypass. Anesthesia & Analgesia 85:4, pages 766-782.
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Paul G. Loubser. (1997) Effect of Methylprednisolone on Complement Activation During Heparin Neutralization. Journal of Cardiovascular Pharmacology 29:1, pages 23-27.
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Joseph Sweeney & Andrew HeatonTerry Gourlay & Kenneth M. Taylor. 1995. Clinical Benefits of Leukodepleted Blood Products. Clinical Benefits of Leukodepleted Blood Products 137 151 .
M.C. Seghaye, J. Duchateau, R.G. Grabitz, M.L. Faymonville, B.J. Messmer, K. Buro-Rathsmann & G. von Bernuth. (1993) Complement activation during cardiopulmonary bypass in infants and children. The Journal of Thoracic and Cardiovascular Surgery 106:6, pages 978-987.
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Philippe G. Jorens, Raf De Jongh, Wilfried De Backer, Jo Van Damme, Frans Van Overveld, Leo Bossaert, Paul Walter, Arnold G. Herman & Marc Rampart. (1993) Interleukin-8 Production in Patients Undergoing Cardiopulmonary Bypass: The Influence of Pretreatment with Methylprednisolone. American Review of Respiratory Disease 148:4_pt_1, pages 890-895.
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R. F. De Jongh, W. A. De Backer, R. Mohan, P. G. Jorens & F. J. van Overveld. (1993) Angiotensin-converting enzyme activity in serum and bronchoalveolar lavage fluid after damage to the alveolo-capillary barrier in the human lung. Intensive Care Medicine 19:7, pages 390-394.
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Peter Garred, Erik Fosse, Magne K. Fagerhol, Vibeke Videm & Tom Eirik Mollnes. (1993) Calprotectin and complement activation during major operations with or without cardiopulmonary bypass. The Annals of Thoracic Surgery 55:3, pages 694-699.
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F. J. Overveld, R. F. Jongh, P. G. Jorens, P. Walter, L. Bossaert & W. A. Backer. (1993) Histamine and tryptase in serum of patients after coronary surgery: influence of pretreatment with methylprednisolone. Agents and Actions 38:3-4, pages C278-C280.
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John Butler, Graeme M. Rocker & Stephen Westaby. (1993) Inflammatory response to cardiopulmonary bypass. The Annals of Thoracic Surgery 55:2, pages 552-559.
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Thomas V. Bilfinger. (1993) Complement activation during extracorporeal circulation. Advances in Neuroimmunology 3:4, pages 269-276.
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K. MIKAWA, N. MAEKAWA, J. IKEGAKI, R. GOTO, H. YAKU & H. OBARA. (2007) Peri‐operative changes in plasma C3a and C5a concentrations in infants. Pediatric Anesthesia 2:2, pages 123-131.
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Vibeke Videm, Jan L. Svennevig, Erik Fosse, Gudmund Semb, Arne østerud, Tom Eirik Mollnes & Hans Nielsen. (1992) Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations. The Journal of Thoracic and Cardiovascular Surgery 103:4, pages 806-813.
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Vibeke Videm. (1989) Reply to the Editor: Invited letter concerning: Complement activation caused by different oxygenators. The Journal of Thoracic and Cardiovascular Surgery 98:2, pages 295.
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