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M3 muscarinic acetylcholine receptor reactive IL-17 producing T cells promotes development of Sjögren's syndrome like sialadenitis

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Pages 158-160 | Received 10 Dec 2013, Accepted 13 Jan 2014, Published online: 04 Mar 2014

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Hanae Kudo, Hiroto Tsuboi, Hiromitsu Asashima, Hiroyuki Takahashi, Yuko Ono, Saori Abe, Fumika Honda, Yuya Kondo, Yuhya Wakasa, Fumio Takaiwa, Makoto Takano, Minoru Matsui, Isao Matsumoto & Takayuki Sumida. (2020) Transgenic rice seeds expressing altered peptide ligands against the M3 muscarinic acetylcholine receptor suppress experimental sialadenitis-like Sjögren’s syndrome. Modern Rheumatology 30:5, pages 884-893.
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Mary L. Williams. (2021) Global warming, heat-related illnesses, and the dermatologist. International Journal of Women's Dermatology 7:1, pages 70-84.
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Saori Abe, Hiroto Tsuboi, Hanae Kudo, Hiromitsu Asashima, Yuko Ono, Fumika Honda, Hiroyuki Takahashi, Mizuki Yagishita, Shinya Hagiwara, Yuya Kondo, Isao Matsumoto & Takayuki Sumida. (2020) M3 muscarinic acetylcholine receptor–reactive Th17 cells in primary Sjögren’s syndrome. JCI Insight 5:15.
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Yuko Ono, Hiroto Tsuboi, Masafumi Moriyama, Hiromitsu Asashima, Hanae Kudo, Hiroyuki Takahashi, Fumika Honda, Saori Abe, Yuya Kondo, Satoru Takahashi, Isao Matsumoto, Seiji Nakamura & Takayuki Sumida. (2020) RORγt antagonist improves Sjögren's syndrome‐like sialadenitis through downregulation of CD25. Oral Diseases 26:4, pages 766-777.
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Anthony J. Bron, Cintia S. de Paiva, Sunil K. Chauhan, Stefano Bonini, Eric E. Gabison, Sandeep Jain, Erich Knop, Maria Markoulli, Yoko Ogawa, Victor Perez, Yuichi Uchino, Norihiko Yokoi, Driss Zoukhri & David A. Sullivan. (2017) TFOS DEWS II pathophysiology report. The Ocular Surface 15:3, pages 438-510.
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M Tahara, H Tsuboi, S Segawa, H Asashima, M Iizuka-Koga, T Hirota, H Takahashi, Y Kondo, M Matsui, I Matsumoto & T Sumida. (2017) RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sjögren's syndrome-like sialadenitis. Clinical and Experimental Immunology 187:2, pages 213-224.
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Lin Yang, Yongfu Wang, Rui Xing, Li Bai, Changhong Li, Zhengqian Li & Xiangyuan Liu. (2016) Mimotope mimicking epidermal growth factor receptor alleviates mononuclear cell infiltration in exocrine glands induced by muscarinic acetylcholine 3 receptor. Clinical Immunology 163, pages 111-119.
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Hiromitsu Asashima, Hiroto Tsuboi, Hiroyuki Takahashi, Tomoya Hirota, Mana Iizuka, Yuya Kondo, Minoru Matsui, Isao Matsumoto & Takayuki Sumida. (2015) The Anergy Induction of M3 Muscarinic Acetylcholine Receptor-Reactive CD4+ T Cells Suppresses Experimental Sialadenitis-like Sjögren's Syndrome. Arthritis & Rheumatology 67:8, pages 2213-2225.
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