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Human Fertility
an international, multidisciplinary journal dedicated to furthering research and promoting good practice
Volume 17, 2014 - Issue 3
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Review Article

‘The BRCA Clock is Ticking!’: Negotiating medical concerns and reproductive goals in preimplantation genetic diagnosis

Lisa R. RubinDepartment of Psychology, New School for Social Research, New York, NY, USACorrespondence[email protected]
,
Allison Werner-LinThe School of Social Policy and Practice, University of Pennsylvania, Philadelphia, PA, USA
,
Michal SagiDepartment of Human Genetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
,
Ina CholstRonald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA
,
Rikki SternSchool of Law, New York University, New York, NY, USA
,
Debra LilienthalRonald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY, USA
&
Karen HurleyDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center and Clinical Psychologist Private Practice, New York, NY, USA
 show all
Pages 159-164 | Received 15 Jul 2013, Accepted 17 Jan 2014, Published online: 08 Aug 2014

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Marleah Dean, Elizabeth A. Hintz, Jonathan Baker, Maija Reblin, Gwendolyn P. Quinn, Carolyn Haskins & Susan T. Vadaparampil. (2023) Shared Decision-Making Experiences of Couples with Inherited Cancer Risk Regarding Family Building. Journal of Health Communication 28:5, pages 292-301.
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Thomas Lemke & Jonas Rüppel. (2019) Social dimensions of preimplantation genetic diagnosis: a literature review. New Genetics and Society 38:1, pages 80-112.
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Articles from other publishers (21)

Mohamed Wafik, Mark David Kilby & Anjana Kulkarni. (2023) Prenatal and pre‐implantation genetic testing for monogenic disorders for germline cancer susceptibility gene variants: UK joint consensus guidance . BJOG: An International Journal of Obstetrics & Gynaecology 130:13, pages 1563-1567.
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Mariam M. AlHilli, Pelin Batur, Karen Hurley, Zahraa Al-Hilli, Demetrius Coombs, Graham Schwarz, Risal Djohan, Jessica Marquard, Kathleen Ashton & Holly J. Pederson. (2023) Comprehensive Care of Women With Genetic Predisposition to Breast and Ovarian Cancer. Mayo Clinic Proceedings 98:4, pages 597-609.
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E. S. Dason, L. Drost, E. M. Greenblatt, A. S. Scheer, J. Han, M. Sobel, L. Allen, M. Jacobson, T. Doshi, E. Wolff, E. McMahon & C. A. Jones. (2022) Providers’ perspectives on the reproductive decision-making of BRCA-positive women. BMC Women's Health 22:1.
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Natalie Vriesen, Erin P. Carmany & Jaime L. Natoli. (2022) Clinical outcomes of preimplantation genetic testing for hereditary cancer syndromes: A systematic review. Prenatal Diagnosis 42:2, pages 201-211.
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Jessica M. Haddad, Katina Robison, Lindsey Beffa, Jessica Laprise, Jennifer ScaliaWilbur, Christina A. Raker, Melissa A. Clark, Erin Hofstatter, Disha Dalela, Amy Brown, Leslie Bradford, Maris Toland & Ashley Stuckey. (2021) Family planning in carriers of BRCA1 and BRCA2 pathogenic variants . Journal of Genetic Counseling 30:6, pages 1570-1581.
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Tara Hughes, Timothy Bracewell-Milnes, Srdjan Saso, Benjamin P Jones, Paula A Almeida, Katherine Maclaren, Julian Norman-Taylor, Mark Johnson & Dimitrios Nikolaou. (2021) A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions. Human Reproduction Update 27:5, pages 944-966.
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Elizabeth Skrovanek, Jacqueline Dunbar-Jacob, Colleen Dunwoody & Susan Wesmiller. (2020) Integrative Review of Reproductive Decision Making of Women Who Are BRCA Positive. Journal of Obstetric, Gynecologic & Neonatal Nursing 49:6, pages 525-536.
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Chaya Possick & Miri Kestler-Peleg. (2019) BRCA and Motherhood: A Matter of Time and Timing. Qualitative Health Research 30:6, pages 825-835.
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Margherita Condorelli & Matteo Lambertini. 2020. Fertility Challenges and Solutions in Women with Cancer. Fertility Challenges and Solutions in Women with Cancer 131 147 .
L M Pastore, C N Cordeiro Mitchell, L R Rubin, J Nicoloro-SantaBarbara, M C Genoff Garzon & M Lobel. (2019) Patients’ preimplantation genetic testing decision-making experience: an opinion on related psychological frameworks. Human Reproduction Open 2019:4.
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Timothy Bracewell-Milnes, Jara Ben-Nagi & Meen-Yau Thum. 2019. Human Embryos and Preimplantation Genetic Technologies. Human Embryos and Preimplantation Genetic Technologies 53 66 .
Kelly Reumkens, Marly H. E. Tummers, Joyce J. G. Gietel-Habets, Sander M. J. van Kuijk, Cora M. Aalfs, Christi J. van Asperen, Margreet G. E. M. Ausems, Margriet Collée, Charlotte J. Dommering, C. Marleen Kets, Lizet E. van der Kolk, Jan C. Oosterwijk, Vivianne C. G. Tjan-Heijnen, Trudy van der Weijden, Christine E. M. de Die-Smulders & Liesbeth A. D. M. van Osch. (2018) The development of an online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making: a usability and pilot study. Familial Cancer 18:1, pages 137-146.
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Pnina Mor, Sarah Brennenstuhl & Kelly A. Metcalfe. (2018) Uptake of Preimplantation Genetic Diagnosis in Female BRCA1 and BRCA2 Mutation Carriers. Journal of Genetic Counseling 27:6, pages 1386-1394.
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M.C. Genoff Garzon, L.R. Rubin, M. Lobel, J. Stelling & L.M. Pastore. (2018) Review of patient decision-making factors and attitudes regarding preimplantation genetic diagnosis. Clinical Genetics 94:1, pages 22-42.
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Marleah Dean & Emily A. Rauscher. (2017) “It was an Emotional Baby”: Previvors’ Family Planning Decision-Making Styles about Hereditary Breast and Ovarian Cancer Risk. Journal of Genetic Counseling 26:6, pages 1301-1313.
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Efrat Dagan, Daphna Birenbaum-Carmeli, Eitan Friedman & Baruch Feldman. (2017) Performing and Declining PGD: Accounts of Jewish Israeli Women Who Carry a BRCA1/2 Mutation or Partners of Male Mutation Carriers. Journal of Genetic Counseling 26:5, pages 1070-1079.
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Matteo Lambertini, Oranite Goldrat, Angela Toss, Hatem A. AzimJr.Jr., Fedro A. Peccatori, Michail Ignatiadis, Lucia Del Mastro & Isabelle Demeestere. (2017) Fertility and pregnancy issues in BRCA -mutated breast cancer patients. Cancer Treatment Reviews 59, pages 61-70.
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M.E. Sabatini. 2017. Translational Advances in Gynecologic Cancers. Translational Advances in Gynecologic Cancers 315 332 .
Lea Hagoel. 2017. Alleviating World Suffering. Alleviating World Suffering 411 422 .
Allison Werner-Lin, Frances K. Barg, Katherine S. Kellom, Kallyn J. Stumm, Lisa Pilchman, Ashley N. Tomlinson & Barbara A. Bernhardt. (2016) Couple’s Narratives of Communion and Isolation Following Abnormal Prenatal Microarray Testing Results. Qualitative Health Research 26:14, pages 1975-1987.
Crossref
Sarah Ross. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 6 .

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