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Research Article

Microwave-assisted synthesis of new benzimidazole derivatives with lipase inhibition activity

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Pages 64-68 | Received 13 Jul 2012, Accepted 30 Sep 2012, Published online: 18 Jan 2013

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Vatsal M. Patel, Navin B. Patel, Manuel J. Chan-Bacab & Gildardo Rivera. (2020) N-Mannich bases of benzimidazole as a potent antitubercular and antiprotozoal agents: Their synthesis and computational studies. Synthetic Communications 50:6, pages 858-878.
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Articles from other publishers (27)

Hakan AKGÜN, Taner İlker GÜMRÜKÇÜOĞLU, Hakan BEKTAŞ & Bahar BİLGİN SÖKMEN. (2023) Yeni Benzimidazol Bileşiklerinin Sentezi, Antioksidan ve Antiüreaz AktiviteleriSynthesis, Antioxidant and Antiurease Activities of Novel Benzimidazole Compounds. Doğu Karadeniz Sağlık Bilimleri Dergisi 2:2, pages 60-76.
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Duygu Ozdes, Celal Duran, Hakan Bektas & Emre Mentese. (2023) A facile and sensitive coprecipitation method coupled with flame atomic absorption spectrometry for quantification of Cu(II) ions in complex matrices. Journal of the Serbian Chemical Society 88:3, pages 301-312.
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Gurumeet C Wadhawa, Sarang Bhagvat, Ramesh Mohite & Yashwant Gaikwad. (2022) An Efficient Synthesis of 2,4,5-Triaryl-1H-Imidazole Derivatives Catalyzed by Boric Acid IN Green Condition. International Journal of Advanced Research in Science, Communication and Technology, pages 255-260.
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Ashwani Kumar & Shilpi Chauhan. (2021) Pancreatic lipase inhibitors: The road voyaged and successes. Life Sciences 271, pages 119115.
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Zeel A. Bhavsar, Prachi T. Acharya, Divya J. Jethava, Dhaval B. Patel, Mahesh S. Vasava, Dhanji P. Rajani, Edwin Pithawala & Hitesh D. Patel. (2020) Microwave assisted synthesis, biological activities, and in silico investigation of some benzimidazole derivatives. Journal of Heterocyclic Chemistry 57:12, pages 4215-4238.
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B. Kahveci, İ. S. Doğan, E. Menteşe, H. E. Sellitepe & D. Kart. (2020) Synthesis and Antibacterial and Antifungal Activity of New Thieno[2,3-d]Pyrimidin-4(3H)-One Derivatives. Pharmaceutical Chemistry Journal 54:6, pages 647-653.
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Emre Menteşe, Nimet Baltaş & Mustafa Emirik. (2020) Synthesis, α-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives. Bioorganic Chemistry 101, pages 104002.
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Martha M. Morcoss, El Shimaa M.N. Abdelhafez, Reham A. Ibrahem, Hamdy M. Abdel-Rahman, Mohamed Abdel-Aziz & Dalal A. Abou El-Ella. (2020) Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents. Bioorganic Chemistry 101, pages 103956.
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Smita Verma, Vishnuvardh Ravichandiran, Nihar Ranjan & Swaran J.S. Flora. (2020) Recent Advances in Therapeutic Applications of Bisbenzimidazoles. Medicinal Chemistry 16:4, pages 454-486.
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Hakan Bektaş, Bahar B. Sökmen, Sinem Aydın, Emre Menteşe, Adile Bektaş & Gamze Dilekçi. (2020) Design, synthesis, and characterization of some new benzimidazole derivatives and biological evaluation. Journal of Heterocyclic Chemistry 57:5, pages 2234-2242.
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Emre Menteşe & Bahar Bilgin Sökmen. (2019) Synthesis and In Vitro Urease Inhibition of Some Novel Benzimidazole‐based Hydrazones . Journal of Heterocyclic Chemistry 56:9, pages 2442-2448.
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Emre Menteşe, Mustafa Emirik & Bahar Bilgin Sökmen. (2019) Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors. Bioorganic Chemistry 86, pages 151-158.
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Şafak Akın, Elif Ayazoglu Demir, Ahmet Colak, Yakup Kolcuoglu, Nuri Yildirim & Olcay Bekircan. (2019) Synthesis, biological activities and molecular docking studies of some novel 2,4,5-trisubstituted-1,2,4-triazole-3-one derivatives as potent tyrosinase inhibitors. Journal of Molecular Structure 1175, pages 280-286.
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Hamid Mostafavi, Mohammad Reza Islami, Ehsan Ghonchepour & Ahmad Momeni Tikdari. (2018) Synthesis of 1H-1,3-benzimidazoles, benzothiazoles and 3H-imidazo[4,5-c]pyridine using DMF in the presence of HMDS as a reagent under the transition-metal-free condition. Chemical Papers 72:12, pages 2973-2978.
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Hakan Bektas, Canan Albay, Bahar Bilgin Sökmen, Sinem Aydın, Emre Menteşe, Gülbahar Aydın & Dilem Şen. (2018) Synthesis, Antioxidant, and Antibacterial Activities of Some New 2-(3-fluorobenzyl)-1 H -benzimidazole Derivatives . Journal of Heterocyclic Chemistry 55:10, pages 2400-2407.
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Rajesh Radhamanalan, Manikandan Alagumuthu & Narsimaiah Nagaraju. (2018) Synthesis and drug efficacy validations of racemic-substituted benzimidazoles as antiulcer/antigastric secretion agents. Future Medicinal Chemistry 10:15, pages 1805-1820.
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Ashwani Kumar & Shilpi Chauhan. (2018) Use of Simplified Molecular Input Line Entry System and molecular graph based descriptors in prediction and design of pancreatic lipase inhibitors. Future Medicinal Chemistry 10:13, pages 1603-1622.
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Emre Menteşe, Fatih Yılmaz, Mustafa Emirik, Serdar Ülker & Bahittin Kahveci. (2018) Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors. Bioorganic Chemistry 76, pages 478-486.
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Günay Kaya Kantar, Özlem Faiz, Onur Şahin & Selami Şaşmaz. (2017) Phthalocyanine and azaphthalocyanines containing eugenol: synthesis, DNA interaction and comparison of lipase inhibition properties. Journal of Chemical Sciences 129:8, pages 1247-1256.
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Emre Menteşe, Hakan Bektaş, Bahar Bilgin Sokmen, Mustafa Emirik, Demet Çakır & Bahittin Kahveci. (2017) Synthesis and molecular docking study of some 5,6-dichloro-2-cyclopropyl-1 H -benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease. Bioorganic & Medicinal Chemistry Letters 27:13, pages 3014-3018.
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İnci S. Doğan, Arzu Özel, Zeynep Birinci, Burak Barut, Hasan E. Sellitepe & Bahittin Kahveci. (2016) Synthesis of Some Novel 2-Substitutedbenzyl-(4)7-phenyl-1 H -benzo[d]imidazoles in Mild Conditions as Potent Anti-Tyrosinase and Antioxidant Agents . Archiv der Pharmazie 349:11, pages 881-888.
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Emre Menteşe, Fatih Yılmaz, Fatih Mutlu & Bahittin Kahveci. (2015) Synthesis of New Coumarin Containing Benzimidazole Derivatives. Journal of Chemical Research 39:11, pages 645-648.
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Fatmah Alasmary, Anna Snelling, Mohammed Zain, Ahmed Alafeefy, Amani Awaad & Nazira Karodia. (2015) Synthesis and Evaluation of Selected Benzimidazole Derivatives as Potential Antimicrobial Agents. Molecules 20:8, pages 15206-15223.
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E. Menteşe, S. Ülker & B. Kahveci. (2015) Synthesis and Study of α-Glucosidase Inhibitory, Antimicrobial and Antioxidant Activities of Some Benzimidazole Derivatives Containing Triazole, Thiadiazole, Oxadiazole, and Morpholine Rings. Chemistry of Heterocyclic Compounds 50:12, pages 1671-1682.
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Musa Özil, Osman Bodur, Serdar Ülker & Bahittin Kahveci. (2015) Microwave-promoted synthesis and biological activity of some 2-hetarylmethyl-4-(4-hetarylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one derivatives. Chemistry of Heterocyclic Compounds 51:1, pages 88-96.
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E. Menteşe, F. Yılmaz, N. Karaali, S. Ülker & B. Kahveci. (2014) Rapid synthesis and lipase inhibition activity of some new benzimidazole and perimidine derivatives. Russian Journal of Bioorganic Chemistry 40:3, pages 336-342.
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Emre Mentese, Fatih Islamoglu, Esra Bal & Bahittin Kahveci. (2013) Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media. European Journal of Chemistry 4:1, pages 25-28.
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