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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 31, 2016 - Issue sup1
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Research Article

Synthesis, cytotoxic, anti-lipoxygenase and anti-acetylcholinesterase capacities of novel derivatives from harmine

Insaf FilaliLaboratoire de Chimie Hétérocyclique, Produits Naturels et Réactivité (CHPNR), Equipe Chimie Médicinale et Produits Naturels Département de Chimie, Faculté des Sciences de Monastir, Université de, Monastir, Tunisie, and ;Laboratoire des IMRCP UMR CNRS, Faculté de pharmacie de Toulouse, Université de Toulouse, Université Paul-Sabatier, Toulouse, France
,
Mohamed Amine BelkacemLaboratoire de Chimie Hétérocyclique, Produits Naturels et Réactivité (CHPNR), Equipe Chimie Médicinale et Produits Naturels Département de Chimie, Faculté des Sciences de Monastir, Université de, Monastir, Tunisie, and ;Laboratoire des IMRCP UMR CNRS, Faculté de pharmacie de Toulouse, Université de Toulouse, Université Paul-Sabatier, Toulouse, France
,
Aymen Ben NejmaLaboratoire de Chimie Hétérocyclique, Produits Naturels et Réactivité (CHPNR), Equipe Chimie Médicinale et Produits Naturels Département de Chimie, Faculté des Sciences de Monastir, Université de, Monastir, Tunisie, and
,
Jean Pierre SouchardLaboratoire des IMRCP UMR CNRS, Faculté de pharmacie de Toulouse, Université de Toulouse, Université Paul-Sabatier, Toulouse, France
,
Hichem Ben JannetLaboratoire de Chimie Hétérocyclique, Produits Naturels et Réactivité (CHPNR), Equipe Chimie Médicinale et Produits Naturels Département de Chimie, Faculté des Sciences de Monastir, Université de, Monastir, Tunisie, and Correspondence[email protected]
&
Jalloul BouajilaLaboratoire des IMRCP UMR CNRS, Faculté de pharmacie de Toulouse, Université de Toulouse, Université Paul-Sabatier, Toulouse, FranceCorrespondence[email protected]
Pages 23-33 | Received 11 Nov 2015, Accepted 02 Mar 2016, Published online: 30 Mar 2016

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Liang Guo, Qin Ma, Wei Chen, Wenxi Fan, Jie Zhang & Bin Dai. (2019) Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 375-387.
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João L. P. Ribeiro, Joana B. Loureiro, Susana M. M. Lopes, Lucília Saraiva & Teresa M. V. D. Pinho e Melo. (2022) 3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents. Pharmaceuticals 15:12, pages 1510.
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Dongyan Hu, Guangtian Han, Huazhong Ren, Xinwei Li, Xi'an Li, Lirong Yue, Jiao Xu, Jiafu Feng & Li Guo. (2022) Synthesis, biological evaluation and preliminary mechanisms of 6-amino substituted harmine derivatives as potential antitumor agents. Fitoterapia 163, pages 105329.
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Tohfa Nasibova. (2022) Cancer Statistics and Anticancer Potential of Peganum harmala Alkaloids: A Review. Borneo Journal of Pharmacy 5:1, pages 71-80.
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Kristina Pavić, Maja Beus, Goran Poje, Lidija Uzelac, Marijeta Kralj & Zrinka Rajić. (2021) Synthesis and Biological Evaluation of Harmirins, Novel Harmine–Coumarin Hybrids as Potential Anticancer Agents. Molecules 26:21, pages 6490.
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Liang Zhang, Dengchang Li & Shenglan Yu. (2020) Pharmacological effects of harmine and its derivatives: a review. Archives of Pharmacal Research 43:12, pages 1259-1275.
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Mansour Znati, Claire Bordes, Valérian Forquet, Pierre Lantéri, Hichem Ben Jannet & Jalloul Bouajila. (2019) Synthesis, molecular properties, anti-inflammatory and anticancer activities of novel 3-hydroxyflavone derivatives. Bioorganic Chemistry 89, pages 103009.
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Monaj Karar, Suvendu Paul, Arabinda Mallick & Tapas Majumdar. (2018) Shipment of a photodynamic therapy agent into model membrane and its controlled release: A photophysical approach. Chemistry and Physics of Lipids 210, pages 122-128.
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Balázs Bálint, Csaba Wéber, Francisco Cruzalegui, Mike Burbridge & Andras Kotschy. (2017) Structure-Based Design and Synthesis of Harmine Derivatives with Different Selectivity Profiles in Kinase versus Monoamine Oxidase Inhibition. ChemMedChem 12:12, pages 932-939.
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Sneharani Athahalli Honnagirig. (2017) Cis-parinaric Acid: A Non-redox Inhibitor of Lipoxygenase-1. Asian Journal of Biochemistry 12:2, pages 27-35.
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