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Research Article

Binding of the Recombinant Proteinase Inhibitor Eglin C from Leech Hzrudo Medzcznalzs to Human Leukocyte Elastase, Bovine α-Chymotrypsin and Subtilisin Carlsberg: Thermodynamic Study

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Pages 167-172 | Received 03 Aug 1987, Published online: 27 Sep 2008

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Paolo Ascenzi, Gino Amiconi, Martino Bolognesi, Silvia Onesti, Raffaele Petruzzelli & Enea Menegatti. (1991) Binding of the Bovine and Porcine Pancreatic Secretory Trypsin Inhibitor (Kazal) To Human Leukocyte Elastase: A Thermodynamic Study. Journal of Enzyme Inhibition 5:3, pages 207-213.
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Kohki Ishida, Makoto Shimizu, Ayumi Wakasugi, Yuko Matsui, Akira Nakamura & Shuichi Kojima. (2022) Development of a novel peptide inhibitor of subtilisin BPN ′ . FEBS Open Bio 12:11, pages 2057-2064.
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Jeffrey J. Gray, Stewart Moughon, Chu Wang, Ora Schueler-Furman, Brian Kuhlman, Carol A. Rohl & David Baker. (2003) Protein?Protein Docking with Simultaneous Optimization of Rigid-body Displacement and Side-chain Conformations. Journal of Molecular Biology 331:1, pages 281-299.
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Hisashi Ishida, Yasumasa Jochi & Akinori Kidera. (1998) Dynamic structure of subtilisin-eglin c complex studied by normal mode analysis. Proteins: Structure, Function, and Genetics 32:3, pages 324-333.
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Yakov E. Dunaevsky, Inna P. Gladysheva, Ekaterina B. Pavlukova, Galina A. Beliakova, Dmitry P. Gladyshev, Alla I. Papisova, Natalja I. Larionova & Mikhail A. Belozersky. (1997) The anionic protease inhibitor BWI-1 from buckwheat seeds. Kinetic properties and possible biological role. Physiologia Plantarum 101:3, pages 483-488.
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J. Janin. 1997. Biomolecular Structure and Dynamics. Biomolecular Structure and Dynamics 3 19 .
A. Wallqvist, R.L. Jernigan & D.G. Covell. (1995) A preference-based free-energy parameterization of enzyme-inhibitor binding. Applications to HIV-1-protease inhibitor design. Protein Science 4:9, pages 1881-1903.
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Joël Janin. (2004) Elusive affinities. Proteins: Structure, Function, and Bioinformatics 21:1, pages 30-39.
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Vincenzo Pavone, Carla Isernia, Michele Saviano, Lucia Falcigno, Angelina Lombardi, Livio Paolillo, Carlo Pedone, Solfrid Buøen, Hilde Merete Naess, Hege Revheim & Jon Amund Eriksen. (1994) Conformational studies on peptides as enzyme inhibitors: chymotrypsin inhibitors using Bowman–Birk type as models. J. Chem. Soc., Perkin Trans. 2:5, pages 1047-1053.
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Qi Long Ying & Sanford R. Simon. (2002) Kinetics of the inhibition of human leukocyte elastase by elafin, a 6-kilodalton elastase-specific inhibitor from human skin. Biochemistry 32:7, pages 1866-1874.
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Francesca Cutruzzolá, Paolo Ascenzi, Donatella Barra, Martino Bolognesi, Enea Menegatti, Paolo Sarti, Hans-Peter Schnebli, Svetlana Tomova & Gino Amiconi. (1993) Selective oxidation of Met-192 in bovine α-chymotrypsin. Effect on catalytic and inhibitor binding properties. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1161:2-3, pages 201-208.
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Karsten Hipler, John P. Priestle, Joseph Rahuel & Markus G. Grütter. (1992) X-ray crystal structure of the serine proteinase inhibitor eglin c at 1.95 Å resolution. FEBS Letters 309:2, pages 139-145.
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Francesco Frigerio, Alessandro Coda, Luisa Pugliese, Claudia Lionetti, Enea Menegatti, Gino Amiconi, Hans Peter Schnebli, Paolo Ascenzi & Martino Bolognesi. (1992) Crystal and molecular structure of the bovine α-chymotrypsin-eglin c complex at 2.0 Å resolution. Journal of Molecular Biology 225:1, pages 107-123.
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Nancy Horton & Mitchell Lewis. (2008) Calculation of the free energy of association for protein complexes. Protein Science 1:1, pages 169-181.
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Paolo Ascenzi, Patrizia Aducci, Gino Amiconi, Alessandro Ballio, Alberto Guaragna, Enea Menegatti, Hans Peter Schnebli & Martino Bolognesi. (1991) Binding of the recombinant proteinase inhibitor eglinc from leechHirudo medicinalis to serine (Pro)enzymes: A comparative thermodynamic study. Journal of Molecular Recognition 4:4, pages 113-119.
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Paolo Ascenzi, Gino Amiconi, Martino Bolognesi, Enea Menegatti & Mario Guarneri. (1990) Binding of the soybean Bowman-Birk proteinase inhibitor and of its chymotrypsin and trypsin inhibiting fragments to bovine α-chymotrypsin and bovine β-trypsin. A thermodynamic study. Journal of Molecular Recognition 3:5-6, pages 192-196.
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Martino Bolognesi, Luisa Pugliese, Giuseppina Gatti, Francesco Frigerio, Alessandro Coda, Luciano Antolini, Hans Peter Schnebli, Enea Menegatti, Gino Amiconi & Paolo Ascenzi. (1990) X-ray crystal structure of the bovine α-chymotrypsin/eglinc complex at 2.6 Å resolution. Journal of Molecular Recognition 3:4, pages 163-168.
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Luisa Pugliese, Giuseppina Gatti, Martino Bolognesi, Alessandro Coda, Enea Menegatti, Hans Peter Schnebli, Paolo Ascenzi & Gino Amiconi. (1989) Preliminary crystallographic data on the complex of bovine ?-chymotrypsin with the recombinant proteinase inhibitor eglin c from Hirudo medicinalis. Journal of Molecular Biology 208:3, pages 511-513.
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