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Journal of Enzyme Inhibition Volume 4, 1991 - Issue 3
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Research Article

Competitive Irreversible Inhibition of Enzymes in the Presence of A Substrate: Scope and Limitations

Ildiko M. Kovach Center of Biomedical Research, University of Kansas, 2099 Constant Avenue, Lawrence, Kansas, 66045
Pages 201-212 | Received 12 Apr 1989, Published online: 27 Sep 2008

Citations (9)

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Read on this site (1)

Diana H. Pliura, Bonnie J. Bonaventura, Henry W. Pauls, John F. Killackey & Allen Krantz. (1992) Irreversible Inhibition of Transglutaminases by Sulfonium Methylketones: Optimization of Specificity and Potency with w-Aminoacyl Spacers. Journal of Enzyme Inhibition 6:3, pages 181-194.
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Articles from other publishers (8)

Alexey Ivanov, Dmitry Stoikov, Insiya Shafigullina, Dmitry Shurpik, Ivan Stoikov & Gennady Evtugyn. (2022) Flow-Through Acetylcholinesterase Sensor with Replaceable Enzyme Reactor. Biosensors 12:9, pages 676.
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Ildiko M. Kovach. (2004) Stereochemistry and secondary reactions in the irreversible inhibition of serine hydrolases by organophosphorus compounds. Journal of Physical Organic Chemistry 17:6-7, pages 602-614.
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Shanqing Zhang, Huijun Zhao & Richard John. (2001) A Theoretical Model for Immobilized Enzyme Inhibition Biosensors. Electroanalysis 13:18, pages 1528-1534.
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Carol Viragh, Ildiko M. Kovach & Lewis Pannell. (1999) Small Molecular Products of Dealkylation in Soman-Inhibited Electric Eel Acetylcholinesterase. Biochemistry 38:30, pages 9557-9561.
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Edith J. Enyedy & Ildiko M. Kovach. (1997) Modulation of human α-thrombin activity with phosphonate ester inhibitors. Bioorganic & Medicinal Chemistry 5:8, pages 1531-1541.
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Qinjian Zhao & Ildiko M Kovach. (1996) Reversible modification of tissue-type plasminogen activator by methylphosphonate esters. Bioorganic & Medicinal Chemistry 4:4, pages 523-529.
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Qinjian Zhao, Ildiko M. Kovach, Akos Bencsura & Adonia Papathanassiu. (2002) Enantioselective and Reversible Inhibition of Trypsin and .alpha.-Chymotrypsin by Phosphonate Esters. Biochemistry 33:26, pages 8128-8138.
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Petr Skládal. (1992) Detection of organophosphate and carbamate pesticides using disposable biosensors based on chemically modified electrodes and immobilized cholinesterase. Analytica Chimica Acta 269:2, pages 281-287.
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