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Review Article

Probiotics in pregnancy and maternal outcomes: a systematic review

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Pages 772-778 | Received 11 Oct 2012, Accepted 29 Nov 2012, Published online: 11 Jan 2013

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Shengtang Qin, Yu Liu, Shuxian Wang, Jingmei Ma & Huixia Yang. (2022) Distribution characteristics of intestinal microbiota during pregnancy and postpartum in healthy women. The Journal of Maternal-Fetal & Neonatal Medicine 35:15, pages 2915-2922.
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Nayara Valiati, Esthela M. Puel, Cristine M. Stefani & Renata M. Lataro. (2023) Does probiotic ingestion reduce the risk of preeclampsia? A systematic review. Applied Physiology, Nutrition, and Metabolism.
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Rita Almeida Teixeira, Cláudia Silva, António Carlos Ferreira, Diana Martins, Adelino Leite-Moreira, Isabel M. Miranda & António S. Barros. (2023) The Association between Gestational Diabetes and the Microbiome: A Systematic Review and Meta-Analysis. Microorganisms 11:7, pages 1749.
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Karima Ncib, Wael Bahia, Nadia Leban, Abdelkarim Mahdhi, Fatma Trifa, Ridha Mzoughi, Anis Haddad, Chédia Jabeur & Gilbert Donders. (2022) Microbial Diversity and Pathogenic Properties of Microbiota Associated with Aerobic Vaginitis in Women with Recurrent Pregnancy Loss. Diagnostics 12:10, pages 2444.
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Setyowati Setyowati, Yati Afiyanti, Imami Nur Rachmawati & Erna Puspita Sari. (2022) Improving Knowledge and Attitudes in Pregnant, Postpartum, and Lactating Women toward Preventing COVID-19 Transmission and Self-Care with Health Education Packages using Android Applications. Open Access Macedonian Journal of Medical Sciences 10:G, pages 625-632.
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Gail Rees, Louise Brough, Gustavo Moya Orsatti, Anna Lodge & Steven Walker. (2022) Do Micronutrient and Omega-3 Fatty Acid Supplements Affect Human Maternal Immunity during Pregnancy? A Scoping Review. Nutrients 14:2, pages 367.
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Mario Fidanza, Pinaki Panigrahi & Tobias R. Kollmann. (2021) Lactiplantibacillus plantarum–Nomad and Ideal Probiotic. Frontiers in Microbiology 12.
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Sarah J Davidson, Helen L Barrett, Sarah A Price, Leonie K Callaway & Marloes Dekker Nitert. (2021) Probiotics for preventing gestational diabetes. Cochrane Database of Systematic Reviews 2021:4.
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Senthil K Vasan, Modou Jobe, Jiji Mathews, Fatoumata Cole, Swathi Rathore, Ousman Jarjou, Dylan Thompson, Alexander Jarde, Mustapha Bittaye, Stanley Ulijaszek, Caroline Fall, Clive Osmond, Andrew Prentice & Fredrik Karpe. (2021) Pregnancy-related interventions in mothers at risk for gestational diabetes in Asian India and low and middle-income countries (PRIMORDIAL study): protocol for a randomised controlled trial. BMJ Open 11:2, pages e042069.
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Yutao Chen, Jun Lu, Kristin Wickens, Thorsten Stanley, Robyn Maude, Peter Stone, Christine Barthow, Julian Crane, Edwin A. Mitchell, Fabrice Merien & Rinki Murphy. (2021) Effect of Lactobacillus rhamnosus Probiotic in Early Pregnancy on Plasma Conjugated Bile Acids in a Randomised Controlled Trial. Nutrients 13:1, pages 209.
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David F. Byrne, Aisling A. Geraghty, Cara A. Yelverton, Eileen F. Murphy, Douwe Van Sinderen, Paul D. Cotter & Fionnuala M. McAuliffe. (2020) The impact of probiotic supplementation on metabolic health in healthy women of reproductive age: a systematic review. Food & Function 11:12, pages 10279-10289.
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Yunxia Niu, Shan Liang, Tao Wang, Xu Hu, Wei Li, Xiaoli Wu & Feng Jin. (2020) Pre‐Gestational intake of Lactobacillus helveticus NS8 has anxiolytic effects in adolescent Sprague Dawley offspring . Brain and Behavior 10:9.
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Sofie Ingdam Halkjær, Victoria Elizabeth de Knegt, Bobby Lo, Lisbeth Nilas, Dina Cortes, Anders Elm Pedersen, Hengameh Chloé Mirsepasi-Lauridsen, Lee O’Brien Andersen, Henrik Vedel Nielsen, Christen Rune Stensvold, Thor Bech Johannesen, Thomas Kallemose, Karen Angeliki Krogfelt & Andreas Munk Petersen. (2020) Multistrain Probiotic Increases the Gut Microbiota Diversity in Obese Pregnant Women: Results from a Randomized, Double-Blind Placebo-Controlled Study. Current Developments in Nutrition 4:7, pages nzaa095.
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Karaponi AM Okesene-Gafa, Abigail E Moore, Vanessa Jordan, Lesley McCowan & Caroline A Crowther. (2020) Probiotic treatment for women with gestational diabetes to improve maternal and infant health and well-being. Cochrane Database of Systematic Reviews 2020:6.
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H. David McIntyre, Patrick Catalano, Cuilin Zhang, Gernot Desoye, Elisabeth R. Mathiesen & Peter Damm. (2019) Gestational diabetes mellitus. Nature Reviews Disease Primers 5:1.
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Ebru GOZUYESIL, Ayten ARIOZ DUZGUN & Mete SUCU. (2019) WOMEN’S CONSUMPTION OF PROBIOTIC FOOD; THE EXAMPLE OF YOGURT AND KEFIR. Clinical and Experimental Health Sciences.
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Alexis B. Dunn, Lisa Hanson, Leona VandeVusse & Sharon Leslie. (2019) Through the Microbial Looking Glass: Premature Labor, Preeclampsia, and Gestational Diabetes. Journal of Perinatal & Neonatal Nursing 33:1, pages 35-51.
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Geoffrey N. Pronovost & Elaine Y. Hsiao. (2019) Perinatal Interactions between the Microbiome, Immunity, and Neurodevelopment. Immunity 50:1, pages 18-36.
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Jacquelyn Grev, Marie Berg & Roger Soll. (2018) Maternal probiotic supplementation for prevention of morbidity and mortality in preterm infants. Cochrane Database of Systematic Reviews 2018:12.
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Minglian Su, Yuanyang Nie, Ruocheng Shao, Shihao Duan, Youhui Jiang, Mingyue Wang, Zhichao Xing, Qun Sun, Xinghui Liu & Wenming Xu. (2018) Diversified gut microbiota in newborns of mothers with gestational diabetes mellitus. PLOS ONE 13:10, pages e0205695.
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Bryan Tungland. 2018. Human Microbiota in Health and Disease. Human Microbiota in Health and Disease 605 647 .
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Jacquelyn Grev, Marie Berg & Roger Soll. (2017) Maternal probiotic supplementation for prevention of morbidity and mortality in preterm infants. Cochrane Database of Systematic Reviews.
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Vadim V. Yerokhin, Branden K. Carr, Guy Sneed & Matt Vassar. (2016) Clinical trials registries are underused in the pregnancy and childbirth literature: a systematic review of the top 20 journals. BMC Research Notes 9:1.
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M. Karamali, F. Dadkhah, M. Sadrkhanlou, M. Jamilian, S. Ahmadi, M. Tajabadi-Ebrahimi, P. Jafari & Z. Asemi. (2016) Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: A randomized, double-blind, placebo-controlled trial. Diabetes & Metabolism 42:4, pages 234-241.
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. 2016. Metabolomics and Microbiomics. Metabolomics and Microbiomics 107 124 .
Neda Dolatkhah, Majid Hajifaraji, Fatemeh Abbasalizadeh, Naser Aghamohammadzadeh, Yadollah Mehrabi & Mehran Mesgari Abbasi. (2015) Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial. Journal of Health, Population and Nutrition 33:1.
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Andrew Szilagyi. (2015) Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases. Nutrients 7:8, pages 6751-6779.
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E. Isolauri, S. Rautava, M. C. Collado & S. Salminen. (2015) Role of probiotics in reducing the risk of gestational diabetes. Diabetes, Obesity and Metabolism 17:8, pages 713-719.
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Karen L. Lindsay, Lorraine Brennan, Maria A. Kennelly, Orla C. Maguire, Thomas Smith, Sinead Curran, Mary Coffey, Michael E. Foley, Mensud Hatunic, Fergus Shanahan & Fionnuala M. McAuliffe. (2015) Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial. American Journal of Obstetrics and Gynecology 212:4, pages 496.e1-496.e11.
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Maria Teresa Gervasi & Gianna Bogana. 2015. Metabolic Syndrome and Complications of Pregnancy. Metabolic Syndrome and Complications of Pregnancy 151 164 .
Enrico Ferrazzi, Valeria Mantegazza, Sara Zullino & Tamara Stampaljia. 2015. Metabolic Syndrome and Complications of Pregnancy. Metabolic Syndrome and Complications of Pregnancy 135 150 .
H. Torjusen, A. L. Brantsaeter, M. Haugen, J. Alexander, L. S. Bakketeig, G. Lieblein, H. Stigum, T. Naes, J. Swartz, G. Holmboe-Ottesen, G. Roos & H. M. Meltzer. (2014) Reduced risk of pre-eclampsia with organic vegetable consumption: results from the prospective Norwegian Mother and Child Cohort Study. BMJ Open 4:9, pages e006143-e006143.
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Karen L Lindsay, Maria Kennelly, Marie Culliton, Thomas Smith, Orla C Maguire, Fergus Shanahan, Lorraine Brennan & Fionnuala M McAuliffe. (2014) Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study). The American Journal of Clinical Nutrition 99:6, pages 1432-1439.
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Karen L. Lindsay, Lorraine Brennan & Fionnuala M. McAuliffe. (2014) Acceptability of and compliance with a probiotic capsule intervention in pregnancy. International Journal of Gynecology & Obstetrics 125:3, pages 279-280.
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Helen L Barrett, Marloes Dekker Nitert, Louise S Conwell & Leonie K Callaway. (2014) Probiotics for preventing gestational diabetes. Cochrane Database of Systematic Reviews.
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MANJU CHANDIRAMANI, PHILLIP R BENNETT, RICHARD BROWN, YUN S LEE & DAVID A. MACINTYRE. (2014) VAGINAL MICROBIOME–PREGNANT HOST INTERACTIONS DETERMINE A SIGNIFICANT PROPORTION OF PRETERM LABOUR. Fetal and Maternal Medicine Review 25:1, pages 73-78.
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K. L. Lindsay, M. Kennelly, M. Culliton, O. C. Maguire, T. Smith, F. Shanahan, L. Brennan & F. M. McAuliffe. (2014) The impact of probiotics in obese pregnancy to reduce maternal fasting glucose: A randomized controlled trial. Proceedings of the Nutrition Society 73:OCE2.
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