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Journal of Pain & Palliative Care Pharmacotherapy Volume 27, 2013 - Issue 2
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CASE REPORT

Oral Ketamine for Sickle Cell Crisis Pain Refractory to Opioids

Cara A. Jennings Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.Correspondence[email protected]
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Barton T. Bobb Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
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Danielle M. Noreika Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
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Patrick J. Coyne Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Pages 150-154 | Received 27 Feb 2013, Accepted 13 Mar 2013, Published online: 21 May 2013

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Samuel N Uwaezuoke, Adaeze C Ayuk, Ikenna K Ndu, Chizoma I Eneh, Ngozi R Mbanefo & Osita U Ezenwosu. (2018) Vaso-occlusive crisis in sickle cell disease: current paradigm on pain management. Journal of Pain Research 11, pages 3141-3150.
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Nicole Palm, Catherine Floroff, Tanna B. Hassig, Alice Boylan & Julie Kanter. (2018) Low-Dose Ketamine Infusion for Adjunct Management during Vaso-occlusive Episodes in Adults with Sickle Cell Disease: A Case Series. Journal of Pain & Palliative Care Pharmacotherapy 32:1, pages 20-26.
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Danielle M. Noreika & Patrick Coyne. (2015) Discontinuance of Life Sustaining Treatment Utilizing Ketamine for Symptom Management. Journal of Pain & Palliative Care Pharmacotherapy 29:1, pages 37-40.
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Articles from other publishers (16)

Mohammad H. Bawany & Sergey M. Motov. (2022) Subdissociative-dose ketamine for sickle cell vaso-occlusive crisis: a narrative review for the emergency physician. Clinical and Experimental Emergency Medicine 9:3, pages 169-175.
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J. Bryan Cooper‐Sood, Ward Hagar, Anne Marsh, Carolyn Hoppe & Anurag K. Agrawal. (2022) Adjuvant low‐dose ketamine for paediatric and young adult sickle cell vaso‐occlusive episodes in the emergency department. British Journal of Haematology 198:1, pages 207-209.
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Jennifer Froomkin, Randall W. Knoebel, David Dickerson, Hailey Soni & Jennifer Szwak. (2021) Impact of Ketamine in the Management of Painful Sickle Cell Disease Vaso-Occlusive Crisis. Hospital Pharmacy 57:1, pages 176-181.
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Mohammed S. Alshahrani, Amal H. AlSulaibikh, Mohamed R. ElTahan, Sukayna Z. AlFaraj, Laila P. Asonto, Abdullah A. AlMulhim, Murad F. AlAbbad, Nisreen Almaghraby, Mohammed A. AlJumaan, Thamir O. AlJunaid, Moath N. Darweesh, Faisal M. AlHawaj, Alaa M. Mahmoud, Bader K. Alossaimi, Shaikhah K. Alotaibi, Talal M. AlMutairi, Duaa A. AlSulaiman PharmD, Dunya Alfaraj, Reem Alhawwas, Lawrence Mbuagbaw, Kim Lewis, Madeleine Verhovsek, Mark Crowther, Gordon Guyatt & Waleed Alhazzani. (2021) Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial. Academic Emergency Medicine 29:2, pages 150-158.
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Emily M. Harris, Emily Vilk, Matthew M. Heeney, Jean Solodiuk, Christine Greco & Natasha M. Archer. (2021) A systematic review of ketamine for the management of vaso‐occlusive pain in sickle cell disease. Pediatric Blood & Cancer 68:7.
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Latika Puri, Kyle J. Morgan & Doralina L. Anghelescu. (2019) Ketamine and lidocaine infusions decrease opioid consumption during vaso-occlusive crisis in adolescents with sickle cell disease. Current Opinion in Supportive & Palliative Care 13:4, pages 402-407.
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Erica B. John, Marc W. Kaufmann, Richard A. Barnhart, Jaime L. Baratta & Eric S. Schwenk. 2019. Academic Pain Medicine. Academic Pain Medicine 167 175 .
Steven P. Cohen, Anuj Bhatia, Asokumar Buvanendran, Eric S. Schwenk, Ajay D. Wasan, Robert W. Hurley, Eugene R. Viscusi, Samer Narouze, Fred N. Davis, Elspeth C. Ritchie, Timothy R. Lubenow & William M. Hooten. (2018) Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. Regional Anesthesia and Pain Medicine, pages 1.
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Eric S. Schwenk, Eugene R. Viscusi, Asokumar Buvanendran, Robert W. Hurley, Ajay D. Wasan, Samer Narouze, Anuj Bhatia, Fred N. Davis, William M. Hooten & Steven P. Cohen. (2018) Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists. Regional Anesthesia and Pain Medicine, pages 1.
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Latika Puri, Kerri A. Nottage, Jane S. Hankins & Doralina L. Anghelescu. (2017) State of the Art Management of Acute Vaso-occlusive Pain in Sickle Cell Disease. Pediatric Drugs 20:1, pages 29-42.
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Felix Anthony Lubega, Mithrika S. DeSilva, Deogratias Munube, Rita Nkwine, Janat Tumukunde, Peter K. Agaba, Mary T. Nabukenya, Fred Bulamba & Tonny S. Luggya. (2018) Low dose ketamine versus morphine for acute severe vaso occlusive pain in children: a randomized controlled trial. Scandinavian Journal of Pain 18:1, pages 19-27.
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Erxia Du, Patrick McAllister, Venugopal Reddy Venna & Liping Xiao. (2017) Clinically Relevant Concentrations of Ketamine Inhibit Osteoclast Formation In Vitro in Mouse Bone Marrow Cultures. Journal of Cellular Biochemistry 118:4, pages 914-923.
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. (2017) An Assessment of the Use, Perceived Benefits, and Outcomes of Ketamine in Sickle Cell Vaso-Occlusive Crisis in the United States. Journal of Hospice & Palliative Nursing 19:1, pages 75-81.
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Eufemia Jacob, Victoria Wong Chan, Christopher Hodge, Lonnie Zeltzer, David Zurakowski & Navil F. Sethna. (2015) Sensory and Thermal Quantitative Testing in Children With Sickle Cell Disease. Journal of Pediatric Hematology/Oncology 37:3, pages 185-189.
Crossref
Deepika S. Darbari, Samir K. Ballas & Daniel J. Clauw. (2014) Thinking beyond sickling to better understand pain in sickle cell disease. European Journal of Haematology 93:2, pages 89-95.
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Dipesh Uprety, Aurangzeb Baber & Maria Foy. (2013) Ketamine infusion for sickle cell pain crisis refractory to opioids: a case report and review of literature. Annals of Hematology 93:5, pages 769-771.
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